scholarly journals Comparative Study about the Efficacy of Low Level Laser Therapy and Curcumin Antimicrobial Photodynamic Therapy as a Coadjuvant Treatment of Oral Mucositis in Oncologic Patients:Antimicrobial, Analgesic and Degree Alteration Effect.

2021 ◽  
Author(s):  
Rita de Cássia Dias Viana Andrade ◽  
THAIS AZEVEDO REIS ◽  
Luciano Pereira Rosa ◽  
Gabriel Pinto de Oliveira Santos ◽  
Francine Cristina da Silva
Keyword(s):  
Photodynamic Therapy ◽  
Laser Therapy ◽  
Oral Mucositis ◽  
Low Level Laser Therapy ◽  
Control Group ◽  
Antimicrobial Photodynamic Therapy ◽  
Blue Led ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Abstract INTRODUCTION: As conventional treatments currently available for mucositis are not considerably effective,there is a need to implement an adjuvant protocol for the treatment of oral mucositis in patients undergoing radiotherapy and chemotherapy.PURPOSE: To evaluate the effect of Low Level Laser Therapy and Antimicrobial Photodynamic Therapy mediated by curcumin and blue LED as an adjunct treatment of oral mucositis foroncology patients using chemotherapy and or radiotherapy.METHODS: Clinical, randomized study, in a single location, in an oncology service of a general hospital, with a total of 30 patients (over 18 years old) with stable oral mucosa lesions in the process of Chemotherapy and or Radiotherapy. The patients were divided into 3 groups: Control group (treated with nystatin), LLLT group (treated with Low Level Laser Therapy), and the aPDT group (treated with 450 nm blue LED and curcumin photosensitizer).RESULTS: The results showed, by means of intra-group comparisons, that the two experimental treatments promoted yeast reduction of the genus Candida in the last two evaluations (21 days and 30 days), but not in the first two evaluations (7 days and 14 days). The intra-group comparisons showed that the Control and aPDT group showed a significant difference in the degree of mucositis over the four evaluations performed, with the results pointing out that the mucositis worsened in the control group from the 14th day, while reduced in the aPDT group from the 21st day of treatment.CONCLUSION: A reduction in the degree of mucositis and pain score was observed in the LLLT and aPDT groups, with the aPDT group standing out when presenting early clinical improvement in relation to the LLLT group and the control group, thus emphasizing its effectiveness within the desired aspects. Regarding the antimicrobial effect, aPDT showed a greater reduction of yeasts of the genus Candida in the tested parameters.

Do Antimicrobial Photodynamic Therapy and Low-Level Laser Therapy Minimize Postoperative Pain and Edema After Molar Extraction?

2020 ◽  
Vol 78 (12) ◽  
pp. 2155.e1-2155.e10
Author(s):  
Renato Silva Fraga ◽  
Lívia Azeredo Alves Antunes ◽  
Walter Luis Soares Fialho ◽  
Maria Isabel Valente ◽  
Cinthya Cristina Gomes ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Postoperative Pain ◽  
Laser Therapy ◽  
Low Level Laser Therapy ◽  
Antimicrobial Photodynamic Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Molar Extraction

Comparison of the efficacy of low-level laser therapy and photodynamic therapy on oral mucositis in rats

2019 ◽  
Vol 34 (7) ◽  
pp. 1483-1491 ◽  
Author(s):  
Suzan Bayer Alinca ◽  
Ebru Saglam ◽  
Nur Ozten Kandas ◽  
Oguzhan Okcu ◽  
Nergiz Yilmaz ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Laser Therapy ◽  
Oral Mucositis ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Comparison between Antimicrobial Photodynamic Therapy and Low-level laser therapy on non-surgical periodontal treatment: A Clinical Study

2020 ◽  
Vol 31 ◽  
pp. 101756 ◽  
Author(s):  
Alice Engel Naves Freire ◽  
Thaisa Macedo Iunes Carrera ◽  
Guilherme José Pimentel Lopes de Oliveira ◽  
Suzane Cristina Pigossi ◽  
Noé Vital Ribeiro Júnior
Keyword(s):  
Photodynamic Therapy ◽  
Clinical Study ◽  
Laser Therapy ◽  
Periodontal Treatment ◽  
Low Level Laser Therapy ◽  
Antimicrobial Photodynamic Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

scholarly journals Osteoradionecrosis of the jaws: case series treated with adjuvant low-level laser therapy and antimicrobial photodynamic therapy

2018 ◽  
Vol 26 (0) ◽  
Author(s):  
Guilherme Henrique Ribeiro ◽  
Mariana Comparotto Minamisako ◽  
Inês Beatriz da Silva Rath ◽  
Aira Maria Bonfim Santos ◽  
Alyne Simões ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Laser Therapy ◽  
Case Series ◽  
Low Level Laser Therapy ◽  
Antimicrobial Photodynamic Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Assessment of healing of dental implant surgical site following Low-Level Laser Therapy using Bio-Clinical parameters: An Exploratory Study

2020 ◽  
Author(s):  
VARSHA PALLED ◽  
DR. JITENDRA RAO ◽  
DR. RAGHUWAR DAYAL SINGH ◽  
DR. SHUCHI TRIPATHI ◽  
DR. KALPANA SINGH ◽  
...  
Keyword(s):  
Laser Therapy ◽  
Test Group ◽  
Low Level Laser Therapy ◽  
Control Group ◽  
Clinical Parameters ◽  
Implant Stability ◽  
Low Level ◽  
Implant Stability Quotient ◽  
Low Level Laser ◽  
Level Laser

The purpose of this study was to evaluate whether Low-Level Laser Therapy (LLLT) improves the healing of the implant surgical site with clinical and biochemical parameters.Thirty patients with an edentulous space spanning a single tooth were selected. The patients were randomly allocated to two groups - the control group and the test group. The test group received laser energy at a power of 2J/cm 2 with a total of 4-6J energy over each implant. Clinical parameters (Implant Stability Quotient, probing index, modified sulcus bleeding index)and osteoprotegerin (OPG) were assessed at baseline and follow-up intervals (2 weeks, 6 weeks, and 3 months).The test group showed significantly higher implant stability quotient compared to thecontrol group at 2 weeks(57.93±3.95 and 35.67±3.08; p<0.01) and 3months(58.86±3.75 and 67.06±3.78; p<0.01). A significant rise in OPG levels of the test group(686.30±125.36pg/ml at baseline and 784.25±108.30pg/ml at 3months;p<0.01) was seen contrary to significant decline in the control group (839.50±249.08pg/ml at baseline,415.30±78.39pg/ml at 3months;p<0.01). Within the limitations of the study, the study suggests that the healing of peri-implant hard and soft tissues may be enhanced with the use of LLLT as an explicit modality during the post-operative period.

scholarly journals High-level evidence exists for low-level laser therapy on chemoradiotherapy-induced oral mucositis in cancer survivors

2013 ◽  
Vol 19 (3) ◽  
pp. 195 ◽  
Author(s):  
SenthilP Kumar ◽  
Krishna Prasad ◽  
Kamalaksha Shenoy ◽  
Mariella D′Souza ◽  
VijayaK Kumar
Keyword(s):  
Cancer Survivors ◽  
Laser Therapy ◽  
Oral Mucositis ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
High Level

Follow-up of pressure ulcer treatment with photodynamic therapy, low level laser therapy and cellulose membrane

2021 ◽  
Vol 30 (4) ◽  
pp. 304-310
Author(s):  
Luciano Pereira Rosa ◽  
Francine Cristina da Silva ◽  
Suzete Carvalho Landulfo Luz ◽  
Regiane Lima Vieira ◽  
Beatriz Rocha Tanajura ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Laser Therapy ◽  
Pressure Ulcer ◽  
Low Level Laser Therapy ◽  
Cellulose Membrane ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Hospitalised Patients

Objective: A pressure ulcer (PU) is an area of tissue trauma caused by continuous and prolonged pressure, often associated with hospitalised patients immobilised due to neurological problems, negatively affecting their quality of life, and burdening the public budget. The aim of this study was to report the follow-up, for 45 weeks, of three patients with neurological lesions due to trauma who subsequently developed PUs, and who were treated with a combination of photodynamic therapy (PDT), low level laser therapy (LLLT) and cellulose membrane (CM). Method: PDT was mediated by the photosensitiser curcumin on a 1.5% emulsion base. Blue LED light at 450 nm was delivered continuously for 12 minutes at an irradiance of 30mW/cm2 and total energy delivered to the tissue was 22J/cm2. LLLT was performed with 660 nm laser, punctuated and continuous, twice a week with parameters: spot size 0.04cm2, power of 40mW, 10 seconds per point, fluence of 10J/cm2 and irradiance of 1000mW/cm2. Results: All PUs had a significant reduction (range: 95.2–100%) of their area after 45 weeks of follow-up and two PUs had complete healing at 20 weeks and 30 weeks. All of the PUs showed a reduction in contamination with the PDT treatments in different proportions. Conclusion: From the results obtained, we conclude that the combination of PDT, LLLT and CM is a promising treatment for PU healing.

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