scholarly journals Effect of Periampullary Diverticulum on Biliary Flora and the Formation of Common Bile Duct Stone

2020 ◽  
Author(s):  
Senlin Hou ◽  
Hao Wang ◽  
Lichao Zhang ◽  
Tingting Yu ◽  
Zhanying Qiao
Keyword(s):  
Bile Duct ◽  
Common Bile Duct ◽  
High Throughput Sequencing ◽  
Bile Duct Stone ◽  
Stone Formation ◽  
Intestinal Flora ◽  
Alpha Diversity ◽  
Intestinal Fluid ◽  
Bacterial Gene ◽  
Periampullary Diverticulum

Abstract Background: Bile duct stone is closely related to periampullary diverticulum, but it is not clear whether the formation of it was affected by the diverticulum through the biliary flora. To explore the diversity and correlation of biliary and intestinal flora in the patients with choledocholithiasis and the effects of periampullary diverticulum on the flora and bile duct stone. Methods: Bile and intestinal fluid were collected from patients with primary common bile duct stones, and then divided into diverticulum group and none- diverticulum group according to the presence or absence of paravertebral diverticula, DNA of these samples was extracted and a bacterial gene library was constructed, and related bioinformatics analysis was performed after high-throughput sequencing to obtain the bacterial components and community structure of the sample. Result: A total of 3001,613 valid sequences were obtained, with an average of 136436.95±3696.842 sequences, which were classified into 6021 ASV/OUT. Alpha diversity analysis showed that the species richness and diversity in the diverticulum group were lower than those in the nondiverticulum group. According to the species annotation results, the advantage bacterium group of the bile is Proteobacteria (BG 80.41%, Bg 70.95%), and advantage bacterium group of the intestinal fluid is Firmicutes and Proteobacteria (BG 89.39%, Bg 74.11%). A large proportion of Enterobacter was found in bile. Escherichia coli, Klebsiella, Streptococcus and other bacteria closely related to stone formation have been found. The proportion of E. coli in the diverticulum group was increased and due to the existence of the diverticulum Enterobacteria in the bile were increased and more complex. The bacteria that produce Betaglucuronidase are found to be increased in bile. Due to the influence of the periampullary diverticulum, the intestinal flora will be changed and then the biliary flora will also change. Conclusion: The existence of periampullary diverticulum will affect the biliary tract flora and lead to the increase of bacteria related to stone formation, which will affect the formation of choledocholithiasis and make it easier for choledocholithiasis to form.

Surgical clip as a nidus for common bile duct stone formation and successful endoscopic therapy

1992 ◽  
Vol 38 (5) ◽  
pp. 611-613 ◽  
Author(s):  
K. Ghazanfari ◽  
Prasad R. Gollapudi ◽  
Frank J. Konicek ◽  
Arturo Olivera ◽  
Manuel Madayag ◽  
...  
Keyword(s):  
Bile Duct ◽  
Common Bile Duct ◽  
Common Bile Duct Stone ◽  
Endoscopic Therapy ◽  
Bile Duct Stone ◽  
Stone Formation ◽  
Surgical Clip

scholarly journals Common Bile Duct Stone Formed around a Migrated Clip: An Unexpected Complication of Laparoscopic Cholecystectomy

2018 ◽  
Vol 2018 ◽  
pp. 1-2 ◽  
Author(s):  
Anas M. Hussameddin ◽  
Iba Ibrahim AlFawaz ◽  
Reema Fahad AlOtaibi
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Bile Duct ◽  
Common Bile Duct ◽  
Endoscopic Retrograde Cholangiopancreatography ◽  
Bile Duct Stone ◽  
Stone Formation ◽  
Endoscopic Retrograde ◽  
Presenting Symptoms ◽  
Surgical Clip ◽  
The Common

Surgical clip migration into the common bile duct with subsequent stone formation is a rare complication following laparoscopic cholecystectomy. Very few cases have been reported in the literature. We report a case of bile duct stone formation around a migrated surgical clip 16 years after laparoscopic cholecystectomy. The patient presented with right upper quadrant pain, fever, and chills for one week. Investigation with abdominal ultrasound showed dilatation of the common bile duct and moderate dilatation of the intrahepatic bile ducts. The diagnosis was confirmed by endoscopic retrograde cholangiopancreatography and the patient was managed successfully with sphincterotomy and stone extraction. The exact mechanism of clip migration is not fully understood. Presenting symptoms are similar to non-clip-induced choledocholithiasis. Time of presentation can vary significantly with an average of 26 months. Most cases reported in the literature required surgical intervention. Clip migration should be considered in the differential diagnosis of postcholecystectomy biliary colic and cholangitis. Management with endoscopic retrograde cholangiopancreatography is the treatment of choice.

scholarly journals Common Bile Duct Stone Formation Induced by Tomato Skin Following Endoscopic Sphincterotomy

Endoscopy ◽  
1994 ◽  
Vol 26 (08) ◽  
pp. 712-712 ◽  
Author(s):  
I. Szántó ◽  
E. M. Gamal ◽  
J. Banai ◽  
A. Bajtai ◽  
I. Bozalyi ◽  
...  
Keyword(s):  
Bile Duct ◽  
Common Bile Duct ◽  
Common Bile Duct Stone ◽  
Endoscopic Sphincterotomy ◽  
Bile Duct Stone ◽  
Stone Formation

scholarly journals ERCP Features and Outcome in Patients with Periampullary Duodenal Diverticulum

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Amir Houshang Mohammad Alizadeh ◽  
Esmaeil Shamsi Afzali ◽  
Anahita Shahnazi ◽  
Mirhadi Mousavi ◽  
Siavash zafar Doagoo ◽  
...  
Keyword(s):  
Bile Duct ◽  
Common Bile Duct ◽  
Endoscopic Retrograde Cholangiopancreatography ◽  
Common Bile Duct Stone ◽  
Clinical Laboratory ◽  
Bile Duct Stone ◽  
Duodenal Diverticulum ◽  
Endoscopic Retrograde ◽  
Periampullary Diverticulum ◽  
Baseline Characteristics

Background. Although periampullary diverticulum is usually asymptomatic and discovered incidentally in patients during endoscopic retrograde cholangiopancreatography (ERCP), it may lead to post-ERCP morbidity. We compared baseline characteristics and clinical data as well as ERCP results in patients with and without periampullary diverticulum. Methods. Clinical, laboratory, and ERCP data of 780 patients referred to the Taleghani Hospital, as a great referral endoscopy center, in Iran were prospectively analyzed. Results. The periampullary diverticulum was identified in 44 patients (5.6%). Cannulation of common bile duct was more failed in patients with diverticulum compared to others (35.5% versus 11.5, P<0.001). Patients with diverticulum had eight times more often common bile duct stone compared to patients without diverticulum (54.5% versus 12.2%, P<0.001). Post-ERCP complications were observed in 2.3% and 4.2% of patients with and without diverticulum, respectively, which did not significantly differ in both groups. Conclusion. Because of more failure cannulation in the presence of periampullary diverticulum, ERCP requires more skills in these patients. Prevalence of common bile duct stone was notably higher in patients with diverticulum; therefore, more assessment of bile stone and its complications in these patients is persistently recommended.

Percutaneous Management of Biliary Stones

2021 ◽  
Vol 38 (03) ◽  
pp. 348-355
Author(s):  
Nevzat Ozcan ◽  
Ahsun Riaz ◽  
Guven Kahriman
Keyword(s):  
Bile Duct ◽  
Common Bile Duct ◽  
Bile Duct Stone ◽  
Stone Formation ◽  
Common Bile Duct Stones ◽  
Percutaneous Treatment ◽  
Stone Disease ◽  
Bile Duct Stones ◽  
Biliary Stones ◽  
Common Causes

AbstractBile duct stone disease is the most common causes of nonmalignant bile duct obstructions. The range of common bile duct stone formation in patients with cholecystectomy is 3 to 14.7%. Hepatolithiasis, although endemic in some parts of the world, is a rare disease that is difficult to manage. Endoscopic intervention is accepted as the first-line management of common bile duct stones. However, when the bile duct cannot be cannulated for various reasons, the endoscopic procedure fails. In this circumstance, percutaneous approach is an alternative technique for the nonsurgical treatment of bile duct stones. This article reviews the indications, technique, outcomes, and complications of the percutaneous treatment of bile duct stone disease.

POST-CHOLECYSTECTOMY CLIP AS A NIDUS FOR COMMON BILE DUCT STONE FORMATION

2020 ◽  
Author(s):  
I Miguel ◽  
E Pijoan ◽  
N Torres ◽  
S Bazaga ◽  
G Torres ◽  
...  
Keyword(s):  
Bile Duct ◽  
Common Bile Duct ◽  
Common Bile Duct Stone ◽  
Bile Duct Stone ◽  
Stone Formation
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