scholarly journals The Role of Peripheral Nerve Function in Age-Related Bone Loss and Changes in Bone Adaptation

2014 ◽  
Author(s):  
Blaine A. Christiansen
Keyword(s):  
Bone Loss ◽  
Peripheral Nerve ◽  
Bone Adaptation ◽  
Nerve Function ◽  
Age Related ◽  
Peripheral Nerve Function

The Role of Schwann Cells in Peripheral Nerve Function, Injury, and Repair

2020 ◽  
pp. 1-22
Author(s):  
Christina M. A. P. Schuh ◽  
Ana Maria Sandoval-Castellanos ◽  
Cristian De Gregorio ◽  
Pamina Contreras-Kallens ◽  
John W. Haycock
Keyword(s):  
Peripheral Nerve ◽  
Schwann Cells ◽  
Nerve Function ◽  
Peripheral Nerve Function ◽  
Injury And Repair

The Role of Schwann Cells in Peripheral Nerve Function, Injury, and Repair

2020 ◽  
pp. 215-236
Author(s):  
Christina M. A. P. Schuh ◽  
Ana Maria Sandoval-Castellanos ◽  
Cristian De Gregorio ◽  
Pamina Contreras-Kallens ◽  
John W. Haycock
Keyword(s):  
Peripheral Nerve ◽  
Schwann Cells ◽  
Nerve Function ◽  
Peripheral Nerve Function ◽  
Injury And Repair

Role of metallothioneins in peripheral nerve function and regeneration

2003 ◽  
Vol 60 (6) ◽  
pp. 1209-1216 ◽  
Author(s):  
D. Ceballos ◽  
N. Lago ◽  
E. Verdú ◽  
M. Penkowa ◽  
J. Carrasco ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Nerve Function ◽  
Peripheral Nerve Function

scholarly journals Chemotherapy-induced peripheral neuropathy: longitudinal analysis of predictors for postural control

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jana Müller ◽  
Charlotte Kreutz ◽  
Steffen Ringhof ◽  
Maximilian Koeppel ◽  
Nikolaus Kleindienst ◽  
...  
Keyword(s):  
Peripheral Neuropathy ◽  
Peripheral Nerve ◽  
Postural Control ◽  
Action Potentials ◽  
Exercise Intervention ◽  
Cross Sectional Study ◽  
Nerve Function ◽  
Cross Sectional ◽  
Peripheral Nerve Function

AbstractImpaired postural control is often observed in response to neurotoxic chemotherapy. However, potential explanatory factors other than chemotherapy-induced peripheral neuropathy (CIPN) have not been adequately considered to date due to primarily cross-sectional study designs. Our objective was to comprehensively analyze postural control during and after neurotoxic chemotherapy, and to identify potential CIPN-independent predictors for its impairment. Postural control and CIPN symptoms (EORTC QLQ-CIPN20) were longitudinally assessed before, during and three weeks after neurotoxic chemotherapy, and in three and six months follow-up examinations (N = 54). The influence of peripheral nerve function as determined by nerve conduction studies (NCS: compound motor action potentials (CMAP) and sensory action potentials (SNAP)), physical activity, and muscle strength on the change in postural control during and after chemotherapy was analyzed by multiple linear regression adjusted for age and body mass index. Postural control, CIPN signs/symptoms, and CMAP/SNAP amplitudes significantly deteriorated during chemotherapy (p < .01). During follow-up, patients recovered from postural instabilities (p < .01), whereas CIPN signs/symptoms and pathologic NCS findings persisted compared to baseline (p < .001). The regression model showed that low CMAP and high SNAP amplitudes at baseline predicted impairment of postural control during but not after chemotherapy. Hence, pre-therapeutically disturbed somatosensory inputs may induce adaptive processes that have compensatory effects and allow recovery of postural control while CIPN signs/symptoms and pathologic peripheral nerve function persist. Baseline NCS findings in cancer patients who receive neurotoxic chemotherapy thus might assist in delineating individual CIPN risk profiles more precisely to which specific exercise intervention programs could be tailor-made.

scholarly journals The Dual Role of Vitamin K2 in “Bone-Vascular Crosstalk”: Opposite Effects on Bone Loss and Vascular Calcification

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1222
Author(s):  
Domitilla Mandatori ◽  
Letizia Pelusi ◽  
Valeria Schiavone ◽  
Caterina Pipino ◽  
Natalia Di Pietro ◽  
...  
Keyword(s):  
Bone Loss ◽  
Vascular Calcification ◽  
Vascular System ◽  
The Elderly ◽  
Food Supplement ◽  
Vitamin K2 ◽  
Bioactive Molecules ◽  
Calcium Deposition ◽  
Age Related

Osteoporosis (OP) and vascular calcification (VC) represent relevant health problems that frequently coexist in the elderly population. Traditionally, they have been considered independent processes, and mainly age-related. However, an increasing number of studies have reported their possible direct correlation, commonly defined as “bone-vascular crosstalk”. Vitamin K2 (VitK2), a family of several natural isoforms also known as menaquinones (MK), has recently received particular attention for its role in maintaining calcium homeostasis. In particular, VitK2 deficiency seems to be responsible of the so-called “calcium paradox” phenomenon, characterized by low calcium deposition in the bone and its accumulation in the vessel wall. Since these events may have important clinical consequences, and the role of VitK2 in bone-vascular crosstalk has only partially been explained, this review focuses on its effects on the bone and vascular system by providing a more recent literature update. Overall, the findings reported here propose the VitK2 family as natural bioactive molecules that could be able to play an important role in the prevention of bone loss and vascular calcification, thus encouraging further in-depth studies to achieve its use as a dietary food supplement.

Peripheral nerve function in patients with familial amyloid polyneuropathy after liver transplantation

Amyloid ◽  
2003 ◽  
Vol 10 (1) ◽  
pp. 17-24 ◽  
Author(s):  
Sachio Kobayashi ◽  
Hiroshi Morita ◽  
Teruko Asawa ◽  
Yo-Ichi Takei ◽  
Takao Hashimoto ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Peripheral Nerve ◽  
Familial Amyloid Polyneuropathy ◽  
Nerve Function ◽  
Amyloid Polyneuropathy ◽  
Peripheral Nerve Function

Beneficial effect of nimodipine on peripheral nerve function in aged rats

1990 ◽  
Vol 11 (4) ◽  
pp. 451-456 ◽  
Author(s):  
C VANDERZEE ◽  
T SCHUURMAN ◽  
R VANDERHOOP ◽  
J TRABER ◽  
W GISPEN
Keyword(s):  
Peripheral Nerve ◽  
Beneficial Effect ◽  
Nerve Function ◽  
Aged Rats ◽  
Peripheral Nerve Function
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