Cell Type Specific Control of Basolateral Amygdala Plasticity Via Entorhinal Cortex Driven Feedforward Inhibition

2018 ◽  
Author(s):  
E. M. Guthman ◽  
Ming Ma ◽  
Philip Chu ◽  
Serapio M. Baca ◽  
Diego Restrepo ◽  
...  
Keyword(s):  
Entorhinal Cortex ◽  
Basolateral Amygdala ◽  
Cell Type ◽  
Cell Type Specific ◽  
Specific Control ◽  
Feedforward Inhibition

scholarly journals Author response: Cell-type-specific control of basolateral amygdala neuronal circuits via entorhinal cortex-driven feedforward inhibition

2019 ◽  
Author(s):  
E Mae Guthman ◽  
Joshua D Garcia ◽  
Ming Ma ◽  
Philip Chu ◽  
Serapio M Baca ◽  
...  
Keyword(s):  
Entorhinal Cortex ◽  
Basolateral Amygdala ◽  
Author Response ◽  
Neuronal Circuits ◽  
Cell Type ◽  
Cell Type Specific ◽  
Specific Control ◽  
Feedforward Inhibition

scholarly journals Cell-type-specific control of basolateral amygdala neuronal circuits via entorhinal cortex-driven feedforward inhibition

eLife ◽  
2020 ◽  
Vol 9 ◽  
Author(s):  
E Mae Guthman ◽  
Joshua D Garcia ◽  
Ming Ma ◽  
Philip Chu ◽  
Serapio M Baca ◽  
...  
Keyword(s):  
Entorhinal Cortex ◽  
Basolateral Amygdala ◽  
Vital Role ◽  
Sensory Stimuli ◽  
Cell Type Specific ◽  
Fast Spiking ◽  
Patch Clamp Electrophysiology ◽  
Unsupervised Cluster Analysis ◽  
Feedforward Inhibition

The basolateral amygdala (BLA) plays a vital role in associating sensory stimuli with salient valence information. Excitatory principal neurons (PNs) undergo plastic changes to encode this association; however, local BLA inhibitory interneurons (INs) gate PN plasticity via feedforward inhibition (FFI). Despite literature implicating parvalbumin expressing (PV+) INs in FFI in cortex and hippocampus, prior anatomical experiments in BLA implicate somatostatin expressing (Sst+) INs. The lateral entorhinal cortex (LEC) projects to BLA where it drives FFI. In the present study, we explored the role of interneurons in this circuit. Using mice, we combined patch clamp electrophysiology, chemogenetics, unsupervised cluster analysis, and predictive modeling and found that a previously unreported subpopulation of fast-spiking Sst+ INs mediate LEC→BLA FFI.

scholarly journals Cell-type-specific control elements of the lymphotropic papovavirus enhancer.

1990 ◽  
Vol 64 (4) ◽  
pp. 1657-1666 ◽  
Author(s):  
J R Erselius ◽  
B Jostes ◽  
A K Hatzopoulos ◽  
L Mosthaf ◽  
P Gruss
Keyword(s):  
Cell Type ◽  
Cell Type Specific ◽  
Lymphotropic Papovavirus ◽  
Specific Control

The Promoter Activity of the Phospholipase C-γ2 Gene Is Regulated by a Cell-Type-Specific Control Element

1997 ◽  
Vol 16 (4) ◽  
pp. 485-492 ◽  
Author(s):  
SEUNG-JAE LEE ◽  
YOUNG YIL BAHK ◽  
DOO HEE YUN ◽  
HE-JIN LEE ◽  
YOUNG HAN LEE ◽  
...  
Keyword(s):  
Phospholipase C ◽  
Promoter Activity ◽  
Control Element ◽  
Cell Type ◽  
A Cell ◽  
Cell Type Specific ◽  
Specific Control ◽  
Γ2 Gene

scholarly journals Cell Type-Specific Control of Neuronal Responsiveness by Gamma-Band Oscillatory Inhibition

2010 ◽  
Vol 30 (6) ◽  
pp. 2150-2159 ◽  
Author(s):  
S. Otte ◽  
A. Hasenstaub ◽  
E. M. Callaway
Keyword(s):  
Gamma Band ◽  
Cell Type ◽  
Cell Type Specific ◽  
Specific Control

scholarly journals Analysis of Excitatory Microcircuitry in the Medial Entorhinal Cortex Reveals Cell-Type-Specific Differences

Neuron ◽  
2010 ◽  
Vol 68 (6) ◽  
pp. 1059-1066 ◽  
Author(s):  
Prateep Beed ◽  
Michael H.K. Bendels ◽  
Hauke F. Wiegand ◽  
Christian Leibold ◽  
Friedrich W. Johenning ◽  
...  
Keyword(s):  
Entorhinal Cortex ◽  
Cell Type ◽  
Medial Entorhinal Cortex ◽  
Cell Type Specific

scholarly journals Cell-Type-Specific Control of Brainstem Locomotor Circuits by Basal Ganglia

Cell ◽  
2016 ◽  
Vol 164 (3) ◽  
pp. 526-537 ◽  
Author(s):  
Thomas K. Roseberry ◽  
A. Moses Lee ◽  
Arnaud L. Lalive ◽  
Linda Wilbrecht ◽  
Antonello Bonci ◽  
...  
Keyword(s):  
Basal Ganglia ◽  
Cell Type ◽  
Cell Type Specific ◽  
Specific Control

scholarly journals Cis-regulatory elements of the mitotic regulator, string/Cdc25

Development ◽  
1999 ◽  
Vol 126 (9) ◽  
pp. 1793-1803 ◽  
Author(s):  
D.A. Lehman ◽  
B. Patterson ◽  
L.A. Johnston ◽  
T. Balzer ◽  
J.S. Britton ◽  
...  
Keyword(s):  
Regulatory Elements ◽  
Cell Type ◽  
Protein Coding ◽  
Cis Acting ◽  
Mitotic Kinase ◽  
Cell Type Specific ◽  
Simple Growth ◽  
Drosophila Cells ◽  
Specific Control ◽  
Control String

Mitosis in most Drosophila cells is triggered by brief bursts of transcription of string (stg), a Cdc25-type phosphatase that activates the mitotic kinase, Cdk1 (Cdc2). To understand how string transcription is regulated, we analyzed the expression of string-lacZ reporter genes covering approximately 40 kb of the string locus. We also tested protein coding fragments of the string locus of 6 kb to 31.6 kb for their ability to complement loss of string function in embryos and imaginal discs. A plethora of cis-acting elements spread over >30 kb control string transcription in different cells and tissue types. Regulatory elements specific to subsets of epidermal cells, mesoderm, trachea and nurse cells were identified, but the majority of the string locus appears to be devoted to controlling cell proliferation during neurogenesis. Consistent with this, compact promotor-proximal sequences are sufficient for string function during imaginal disc growth, but additional distal elements are required for the development of neural structures in the eye, wing, leg and notum. We suggest that, during evolution, cell-type-specific control elements were acquired by a simple growth-regulated promoter as a means of coordinating cell division with developmental processes, particularly neurogenesis.

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