Ertapenem is Non-Inferior to Ceftriaxone for the Treatment of Anogenital Gonorrhea in a Single Intramuscular Dose: The NABOGO Randomized Double Blind Non-Inferiority Trial

2021 ◽  
Author(s):  
Henry John de Vries ◽  
Myrthe de Laat ◽  
Vita W. Jongen ◽  
Titia Heijman ◽  
Carolien M. Wind ◽  
...  
Keyword(s):  
Double Blind ◽  
Intramuscular Dose

A Multiple-Dose, Double-Blind Comparison of Intramuscularly and Orally Administered Ketorolac Tromethamine and Ketogan® in Patients with Pain following Orthopaedic Surgery

1994 ◽  
Vol 22 (4) ◽  
pp. 202-217 ◽  
Author(s):  
P H Gebuhr ◽  
M Soelberg ◽  
W Strauss
Keyword(s):  
Orthopaedic Surgery ◽  
Multiple Dose ◽  
Fixed Time ◽  
Double Blind Study ◽  
Standard Regimen ◽  
Double Blind ◽  
Intramuscular Dose ◽  
Blind Comparison ◽  
Oral Doses ◽  
To Receive

In this multiple-dose, double-blind study 100 patients with moderate, severe or very severe pain following orthopaedic surgery were randomly assigned to receive ketorolac, a nonsteroidal anti-inflammatory drug with potent analgesic properties (10 mg), or the standard regimen of Ketogan® (a combination product containing the narcotic analgesic, ketobemidone, plus a spasmolytic agent) by intramuscular injection every 1 – 6 h as needed for pain. When patients were able to tolerate an oral diet and were expected to respond to oral analgesic medication, based on overall pain sensitivity, they were switched to oral doses of the same medication every 4 – 6 h as needed. A maximum of four daily doses of medication was allowed for up to 10 days. The severity of pain was scored on a five-point scale and was recorded before the first intramuscular dose, at fixed time points therafter for up to 6 h and at the end of each day. Both treatments were effective immediately after the first dose and during the subsequent multiple-dose phase. There were no statistically significant differences between ketorolac and Ketogan®. The results show that 10-mg doses of ketorolac in intramuscular injections followed by 10-mg doses of oral ketorolac are as effective as Ketogan® for the treatment of pain following orthopaedic surgery. Ketorolac appears to be better tolerated than Ketogan® since significantly fewer patients reported adverse events ( P = 0.004) when taking ketorolac.

Double blind trial with a single intramuscular dose of co-trimsxazole before total abdominal hysterectomy

1984 ◽  
Vol 5 (1) ◽  
pp. 49-52 ◽  
Author(s):  
A. R. B. Smith ◽  
T. N. Stanbridge ◽  
G. A. Morewood ◽  
J. Cooper
Keyword(s):  
Total Abdominal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Double Blind Trial ◽  
Double Blind ◽  
Blind Trial ◽  
Intramuscular Dose

Double-blind study of metaxalone; use as skeletal-muscle relaxant

JAMA ◽  
1966 ◽  
Vol 195 (6) ◽  
pp. 479-480 ◽  
Author(s):  
S. Diamond
Keyword(s):  
Skeletal Muscle ◽  
Muscle Relaxant ◽  
Blind Study ◽  
Double Blind Study ◽  
Double Blind ◽  
Skeletal Muscle Relaxant

Discontinuation of antistreptococcal prophylaxis. A double-blind study in rheumatic patients free of heart disease

JAMA ◽  
1966 ◽  
Vol 197 (12) ◽  
pp. 949-952 ◽  
Author(s):  
A. R. Feinstein
Keyword(s):  
Heart Disease ◽  
Blind Study ◽  
Double Blind Study ◽  
Double Blind ◽  
Rheumatic Patients

Clinical efficacy of specific immunotherapy to cat dander: a double-blind placebo-controlled trial

1997 ◽  
Vol 27 (8) ◽  
pp. 860-867 ◽  
Author(s):  
V.A. VARNEY ◽  
J. EDWARDS ◽  
K. TABBAH ◽  
H. BREWSTER ◽  
G. MAVROLEON ◽  
...  
Keyword(s):  
Clinical Efficacy ◽  
Specific Immunotherapy ◽  
Controlled Trial ◽  
Double Blind ◽  
Double Blind Placebo

Baclofen versus clonidine in the treatment of opiates withdrawal, side-effects aspect: a double-blind randomized controlled trial

2001 ◽  
Vol 26 (1) ◽  
pp. 67-71 ◽  
Author(s):  
S. A. Ahmadi-Abhari ◽  
S. Akhondzadeh ◽  
S. M. Assadi ◽  
O. L. Shabestari ◽  
Z. M. Farzanehgan ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Side Effects ◽  
Controlled Trial ◽  
Double Blind ◽  
Randomized Controlled

Combining diclofenac with acetaminophen or acetaminophen-codeine after oral surgery: A randomized, double-blind single-dose study

1999 ◽  
Vol 66 (6) ◽  
pp. 625-635
Author(s):  
E BREIVIK ◽  
P BARKVOLL ◽  
E SKOVLUND
Keyword(s):  
Single Dose ◽  
Oral Surgery ◽  
Double Blind ◽  
Single Dose Study ◽  
Dose Study

Stratilying the risk of clinical upper Gl events in NSAID users: Results from a double-blind outcomes study

2001 ◽  
Vol 120 (5) ◽  
pp. A105-A105 ◽  
Author(s):  
L LAINE ◽  
C HAWKEY ◽  
C BOMBARDIER ◽  
D SHAPIRO ◽  
A REICIN
Keyword(s):  
Double Blind ◽  
Outcomes Study

Oral budenosid is highly effective in the treatment of collagenous colitis: A randomized, double-blind, placebo-controlled, multicenter trial

2001 ◽  
Vol 120 (5) ◽  
pp. A40-A40 ◽  
Author(s):  
S MIEHLKE ◽  
P HEYMER ◽  
T OCHSENKUEHN ◽  
E BAESTLEIN ◽  
G YARIAN ◽  
...  
Keyword(s):  
Collagenous Colitis ◽  
Multicenter Trial ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Highly Effective
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