scholarly journals Islet Autoantibodies in the Patients with Sjogren’s Syndrome and Thyroid Disease and Risk of Progression to Latent Autoimmune Diabetes in Adults: A Case Series

2021 ◽  
Vol Volume 14 ◽  
pp. 1025-1033
Author(s):  
Song Wen ◽  
Wenjing Jiang ◽  
Ligang Zhou
Keyword(s):  
Thyroid Disease ◽  
Sjögren's Syndrome ◽  
Autoimmune Diabetes ◽  
Case Series ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Islet Autoantibodies ◽  
Latent Autoimmune Diabetes ◽  
Risk Of Progression ◽  
Sjögren‘S Syndrome

scholarly journals Hypokalemic quadriparesis due to renal tubular acidosis in a patient with Sjögren’s syndrome: A case series

2014 ◽  
Vol 3 (1) ◽  
pp. 30-33
Author(s):  
Abhishek Maskey ◽  
Neeraj Singh ◽  
Santosh Gautam ◽  
Prashant Bhattarai ◽  
Prakash Poudyal ◽  
...  
Keyword(s):  
Sjögren’S Syndrome ◽  
Renal Tubular Acidosis ◽  
Sjögren's Syndrome ◽  
Renal Involvement ◽  
Case Series ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Life Threatening ◽  
Renal Tubular ◽  
Sjögren‘S Syndrome

We report two cases of female patients presented with hypokalemia secondary to renal tubular acidosis. Sjögren’s syndrome was diagnosed in both the patients on the basis of histopathological and autoantibodies tests. The patients were treated with potassium and bicarbonate supplementation. Renal involvement in Sjögren’s syndrome is not uncommon and may precede sicca complaints. The pathology in most cases is a tubulointerstitial nephritis causing distal renal tubular acidosis and rarely, hypokalemic paralysis. The complications of renal tubular acidosis include life threatening hypokalemia, nephrolithiasis, chronic renal failure, growth retardation and osteomalacia. These consequences can be avoided if the diagnosis is made early and lifelong potassium and alkali supplementation is initiated. Primary Sjögren’s syndrome should be considered in women with acute weakness and hypokalemia. DOI: http://dx.doi.org/10.3126/jaim.v3i1.10701 Journal of Advances in Internal Medicine 2014;03(01):30-33

Renal Tubular Acidosis in Sjögren's Syndrome: A Case Series

2014 ◽  
Vol 40 (2) ◽  
pp. 123-130 ◽  
Author(s):  
Rapur Ram ◽  
Gudithi Swarnalatha ◽  
Kaligotla Venkata Dakshinamurty
Keyword(s):  
Sjögren’S Syndrome ◽  
Renal Tubular Acidosis ◽  
Sjögren's Syndrome ◽  
Case Series ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Renal Tubular ◽  
Sjögren‘S Syndrome

scholarly journals Increased risk of thyroid disease in patients with Sjogren's syndrome: a systematic review and meta-analysis

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e6737 ◽  
Author(s):  
Xin Sun ◽  
Li Lu ◽  
Yanbin Li ◽  
Rong Yang ◽  
Ling Shan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Sjögren’S Syndrome ◽  
Thyroid Disease ◽  
Fixed Effects ◽  
Sjögren's Syndrome ◽  
Meta Analysis ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Increased Risk ◽  
Sjögren‘S Syndrome

Background Sjogren’s syndrome (SS) is a chronic autoimmune epithelitis characterized by disruption of epithelial cells, ensuing lymphoplasmocytic infiltration of exocrine glands, and subsequent dryness of the mouth and eyes. Individuals with SS are more likely to have the thyroid disease. However, this association remains controversial. This meta-analysis aimed to evaluate the risk of thyroid disease in patients with SS. Methods We performed this systematic review by searching both English and Chinese literature databases. Random- or fixed-effects models were used to summarize the association between thyroid disease and SS. The results were subjected to meta-analysis with odds ratios (ORs) and corresponding 95% confidence intervals (CIs). Results The eight articles in this meta-analysis included 988 SS cases and 2,884 controls. Overall, the risk of thyroid disease in patients with SS was significantly increased compared with controls (OR, 3.29; 95% CI [2.08–5.21]). The risk of autoimmune thyroid disease (AITD) and non-AITD were also higher in patients with SS than in controls (OR, 3.48; 95% CI [1.59–7.63]; and OR, 2.90; 95% CI [1.51–5.57], respectively). Conclusions To the best of our knowledge, this systematic review is the first to demonstrate that the risk of thyroid disease was increased in SS compared to controls, suggesting that SS patients should be screened for thyroid disease.

Sign in / Sign up

Export Citation Format

Share Document