scholarly journals Assessment of Gold-Coated Iron Oxide Nanoparticles as Negative T2 Contrast Agent in Small Animal MRI Studies

2020 ◽  
Vol Volume 15 ◽  
pp. 4811-4824 ◽  
Author(s):  
Stefania D Iancu ◽  
Camelia Albu ◽  
Liviu Chiriac ◽  
Remus Moldovan ◽  
Andrei Stefancu ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Contrast Agent ◽  
Iron Oxide Nanoparticles ◽  
Small Animal ◽  
Oxide Nanoparticles ◽  
Mri Studies ◽  
Small Animal Mri

In vitroandex vivoevaluation of silica-coated super paramagnetic iron oxide nanoparticles (SPION) as biomedical photoacoustic contrast agent

2013 ◽  
Author(s):  
Rudolf Alwi ◽  
Sergey A. Telenkov ◽  
Andreas Mandelis ◽  
Timothy Leshuk ◽  
Frank Gu ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Contrast Agent ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Super Paramagnetic Iron Oxide

PEGylated superparamagnetic iron oxide nanoparticles labeled with 68Ga as a PET/MRI contrast agent: a biodistribution study

2016 ◽  
Vol 311 (1) ◽  
pp. 769-774 ◽  
Author(s):  
Afsaneh Lahooti ◽  
Saeed Sarkar ◽  
Hamidreza Saligheh Rad ◽  
Amir Gholami ◽  
Sahar Nosrati ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Contrast Agent ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Biodistribution Study ◽  
Mri Contrast Agent ◽  
Oxide Nanoparticles ◽  
Mri Contrast

Quantitative renal cortical perfusion in human subjects with magnetic resonance imaging using iron-oxide nanoparticles: influence of t1 shortening

2008 ◽  
Vol 49 (8) ◽  
pp. 955-962 ◽  
Author(s):  
A. Morell ◽  
H. Ahlstrom ◽  
S. O. Schoenberg ◽  
A. Abildgaard ◽  
M. Bock ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Contrast Agent ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Quantitative Perfusion ◽  
Intravascular Contrast Agent ◽  
Cortical Perfusion

Background: Using conventional contrast agents, the technique of quantitative perfusion by observing the transport of a bolus with magnetic resonance imaging (MRI) is limited to the brain due to extravascular leakage. Purpose: To perform quantitative perfusion measurements in humans with an intravascular contrast agent, and to estimate the influence of the T1 relaxivity of the contrast agent on the first-pass response. Material and Methods: Renal cortical perfusion was measured quantitatively in six patients with unilateral renal artery stenosis using a rapid gradient double-echo sequence in combination with an intravenous bolus injection of NC100150 Injection, an intravascular contrast agent based on iron-oxide nanoparticles. The influence of T1 relaxivity was measured by comparing perfusion results based on single- and double-echo data. Results: The mean values of cortical blood flow, cortical blood volume, and mean transit time in the normal kidneys were measured to 339±60 ml/min/100 g, 41±8 ml/100 g, and 7.3±1.0 s, respectively, based on double-echo data. The corresponding results based on single-echo data, which are not compensated for the T1 relaxivity, were 254±47 ml/min/100 g, 27±3 ml/100 g, and 6±1.2 s, respectively. Conclusion: The use of a double-echo sequence enabled elimination of confounding T1 effects and consequent systematic underestimation of the perfusion.

In situ preparation of high relaxivity iron oxide nanoparticles by coating with chitosan: A potential MRI contrast agent useful for cell tracking

2010 ◽  
Vol 322 (2) ◽  
pp. 208-213 ◽  
Author(s):  
Zei-Tsan Tsai ◽  
Jen-Fei Wang ◽  
Hsiao-Yun Kuo ◽  
Chia-Rui Shen ◽  
Jiun-Jie Wang ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Contrast Agent ◽  
Iron Oxide Nanoparticles ◽  
Cell Tracking ◽  
Mri Contrast Agent ◽  
Oxide Nanoparticles ◽  
Mri Contrast ◽  
In Situ Preparation ◽  
High Relaxivity

Iron oxide nanoparticles for use as an MRI contrast agent: Pharmacokinetics and metabolism

1991 ◽  
Vol 9 (3) ◽  
pp. 275-283 ◽  
Author(s):  
D. Pouliquen ◽  
J.J. Le Jeune ◽  
R. Perdrisot ◽  
A. Ermias ◽  
P. Jallet
Keyword(s):  
Iron Oxide ◽  
Contrast Agent ◽  
Iron Oxide Nanoparticles ◽  
Mri Contrast Agent ◽  
Oxide Nanoparticles ◽  
Mri Contrast

Gd(iii) complex conjugated ultra-small iron oxide as an enhanced T1-weighted MR imaging contrast agent

2015 ◽  
Vol 3 (7) ◽  
pp. 1433-1438 ◽  
Author(s):  
Li Wang ◽  
Hongwei Zhang ◽  
Zhiguo Zhou ◽  
Bin Kong ◽  
Lu An ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Mr Imaging ◽  
Contrast Agent ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Imaging Contrast Agent

In this work, Gd(III) complex conjugated ultra-small iron oxide nanoparticles were simply synthesized and were observed with a novel T1-weight MR imaging enhancement.

scholarly journals Iron oxide nanoparticles stabilized with dendritic polyglycerols as selective MRI contrast agents

Nanoscale ◽  
2014 ◽  
Vol 6 (16) ◽  
pp. 9646-9654 ◽  
Author(s):  
Daniel Nordmeyer ◽  
Patrick Stumpf ◽  
Dominic Gröger ◽  
Andreas Hofmann ◽  
Sven Enders ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Iron Oxide ◽  
Contrast Agent ◽  
Contrast Agents ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Mri Contrast Agents ◽  
Mri Contrast Agent ◽  
Oxide Nanoparticles ◽  
Mri Contrast

Superparamagnetic iron oxide nanoparticles with a dendritic polyglycerol (dPG) sulfate strongly bind to L- and P-selectin. Shielding of leukocytes reduces cell extravasation and binding to endothelial cells indicate inflammation specificity and thus, applicability as selective MRI contrast agent.

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