scholarly journals Clock Gene Nr1d1 Alleviates Retinal Inflammation Through Repression of Hmga2 in Microglia

2021 ◽  
Vol Volume 14 ◽  
pp. 5901-5918
Author(s):  
Zhijie Wang ◽  
Yinhua Huang ◽  
Feixue Chu ◽  
Shangli Ji ◽  
Kai Liao ◽  
...  
Keyword(s):  
Clock Gene ◽  
Retinal Inflammation

The chicken CLOCK gene maps to chromosome 4

2000 ◽  
Vol 31 (5) ◽  
pp. 344-344 ◽  
Author(s):  
M A Noakes ◽  
M T Campbell ◽  
B J Van Hest
Keyword(s):  
Clock Gene ◽  
Chromosome 4 ◽  
Gene Maps

Palmitoylethanolamide treatment reduces retinal inflammation in streptozotocin-induced diabetic rats

2015 ◽  
Vol 769 ◽  
pp. 313-323 ◽  
Author(s):  
Irene Paterniti ◽  
Rosanna Di Paola ◽  
Michela Campolo ◽  
Rosalba Siracusa ◽  
Marika Cordaro ◽  
...  
Keyword(s):  
Diabetic Rats ◽  
Retinal Inflammation

scholarly journals Response to Comment on “Circadian rhythms in the absence of the clock gene Bmal1”

Science ◽  
2021 ◽  
Vol 372 (6539) ◽  
pp. eabf1941
Author(s):  
Sandipan Ray ◽  
Utham K. Valekunja ◽  
Alessandra Stangherlin ◽  
Steven A. Howell ◽  
Ambrosius P. Snijders ◽  
...  
Keyword(s):  
Circadian Rhythms ◽  
Clock Gene ◽  
Statistical Significance ◽  
Statistical Measures ◽  
Statistical Algorithm ◽  
Low Amplitude ◽  
Lines Of Evidence

Abruzzi et al. argue that transcriptome oscillations found in our study in the absence of Bmal1 are of low amplitude, statistical significance, and consistency. However, their conclusions rely solely on a different statistical algorithm than we used. We provide statistical measures and additional analyses showing that our original analyses and observations are accurate. Further, we highlight independent lines of evidence indicating Bmal1-independent 24-hour molecular oscillations.

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