scholarly journals Association of Two Variable Number of Tandem Repeats in the Monoamine Oxidase A Gene Promoter with Schizophrenia

2021 ◽  
Vol Volume 17 ◽  
pp. 3315-3323
Author(s):  
Takaki Tanifuji ◽  
Satoshi Okazaki ◽  
Ikuo Otsuka ◽  
Tadasu Horai ◽  
Yutaka Shinko ◽  
...  
Keyword(s):  
Monoamine Oxidase ◽  
Tandem Repeats ◽  
Gene Promoter ◽  
Variable Number ◽  
Monoamine Oxidase A

scholarly journals Monoamine Oxidase A Promoter Variable Number of Tandem Repeats (MAOA-uVNTR) in Alcoholics According to Lesch Typology

2015 ◽  
Vol 12 (3) ◽  
pp. 3317-3326 ◽  
Author(s):  
Agnieszka Samochowiec ◽  
Magdalena Chęć ◽  
Edyta Kopaczewska ◽  
Jerzy Samochowiec ◽  
Otto Lesch ◽  
...  
Keyword(s):  
Monoamine Oxidase ◽  
Tandem Repeats ◽  
Variable Number ◽  
Monoamine Oxidase A ◽  
Lesch Typology

scholarly journals The Regulation of Monoamine Oxidase A Gene Expression by Distinct Variable Number Tandem Repeats

2018 ◽  
Vol 64 (3) ◽  
pp. 459-470 ◽  
Author(s):  
Maurizio Manca ◽  
Veridiana Pessoa ◽  
Ana Illera Lopez ◽  
Patrick T. Harrison ◽  
Fabio Miyajima ◽  
...  
Keyword(s):  
Gene Expression ◽  
Monoamine Oxidase ◽  
Tandem Repeats ◽  
Variable Number ◽  
Monoamine Oxidase A ◽  
Distinct Variable ◽  
Variable Number Tandem Repeats

scholarly journals Association of variable number of tandem repeats (VNTR) and T941G polymorphism of monoamine oxidase (MAO-A) gene with aggression in Pakistani subjects

2021 ◽  
Vol 21 (1) ◽  
pp. 180-8
Author(s):  
Sumbal Sarwar ◽  
Shabana ◽  
Shahida Hasnain
Keyword(s):  
Monoamine Oxidase ◽  
Promoter Region ◽  
Tandem Repeats ◽  
Variable Number ◽  
Monoamine Oxidase A ◽  
Pakistani Population ◽  
Behavioral Traits ◽  
Genotype Frequencies ◽  
Pcr Rflp ◽  
Mao A

Background: Human behavioral traits are known to be significantly heritable. Certain individuals have a greater tendency of negative behavioral aspects including aggression. The quest to identify tunderlying genetic causes has led to identification of a number of genetic markers, one of them is the monoamine oxidase-A (MAO-A) gene. Objective: We aimed to genotype a variable number of tandem repeats (VNTRs) in the promoter region and a functional SNP within this gene (T941G, dbSNP ID: rs6323) in the recruited cohort of 482 subjects. Methods: After DNA isolation, genotyping was done by PCR-RFLP and the results were confirmed by sequencing. Results: For VNTRs, the results showed, highest frequency of 3.5 repeats in males and 4 repeats in females in the promoter region. The genotype frequencies for the SNP in cases were GG=16.3%, TG=20.6% and TT=63.1%, while in controls, the frequencies were GG=12.7%, TG=6.3%, and TT=81.0%. The allele frequencies were significantly different between cases and controls (p=0.015; OR=1.51; CI=1.085-2.102). Conclusion: The selected VNTR and SNP appeared to be significantly associated with aggression. These VNTRs and SNP have not been studied previously in the Pakistani population, hence they represent a unique ethnic group. These results, however, would have to be replicated in larger cohorts. Keywords: Aggression; MAO-A gene; VNTRs; T941G; rs6323; Pakistan.

scholarly journals Associations of a Regulatory Polymorphism of Monoamine Oxidase-A Gene Promoter (MAOA-uVNTR) With Symptoms of Depression and Sleep Quality

2007 ◽  
Vol 69 (5) ◽  
pp. 396-401 ◽  
Author(s):  
Beverly H. Brummett ◽  
Andrew D. Krystal ◽  
Ilene C. Siegler ◽  
Cynthia Kuhn ◽  
Richard S. Surwit ◽  
...  
Keyword(s):  
Monoamine Oxidase ◽  
Sleep Quality ◽  
Gene Promoter ◽  
Monoamine Oxidase A ◽  
Symptoms Of Depression ◽  
Regulatory Polymorphism

scholarly journals A functional polymorphism in the monoamine oxidase A gene promoter

1998 ◽  
Vol 103 (3) ◽  
pp. 273-279 ◽  
Author(s):  
S. Z. Sabol ◽  
Stella Hu ◽  
D. Hamer
Keyword(s):  
Monoamine Oxidase ◽  
Gene Promoter ◽  
Monoamine Oxidase A ◽  
Functional Polymorphism

scholarly journals Structural variation of the monoamine oxidase A gene promoter repeat polymorphism in nonhuman primates

2005 ◽  
Vol 5 (1) ◽  
pp. 40-45 ◽  
Author(s):  
J. R. Wendland ◽  
M. Hampe ◽  
T. K. Newman ◽  
Y. Syagailo ◽  
J. Meyer ◽  
...  
Keyword(s):  
Monoamine Oxidase ◽  
Structural Variation ◽  
Nonhuman Primates ◽  
Gene Promoter ◽  
Monoamine Oxidase A ◽  
Repeat Polymorphism

scholarly journals HPA axis function in male caregivers: Effect of the monoamine oxidase-A gene promoter (MAOA-uVNTR)

2008 ◽  
Vol 79 (2) ◽  
pp. 250-255 ◽  
Author(s):  
Beverly H. Brummett ◽  
Stephen H. Boyle ◽  
Ilene C. Siegler ◽  
Cynthia M. Kuhn ◽  
Richard S. Surwit ◽  
...  
Keyword(s):  
Monoamine Oxidase ◽  
Hpa Axis ◽  
Gene Promoter ◽  
Monoamine Oxidase A ◽  
Male Caregivers
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