scholarly journals Effect of intrawound vancomycin application in spinal surgery on the incidence of surgical site infection: a meta-analysis

2018 ◽  
Vol Volume 14 ◽  
pp. 2149-2159 ◽  
Author(s):  
Abuduwufuer Tailaiti ◽  
Jun Shang ◽  
Shuo Shan ◽  
Aikeremujiang Muheremu
Keyword(s):  
Surgical Site Infection ◽  
Spinal Surgery ◽  
Meta Analysis ◽  
Site Infection

Risk Factors for Surgical Site Infection After Spinal Surgery: A Meta-Analysis

2016 ◽  
Vol 95 ◽  
pp. 507-515 ◽  
Author(s):  
Qi Fei ◽  
Jinjun Li ◽  
JiSheng Lin ◽  
Dong Li ◽  
BingQiang Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Surgical Site Infection ◽  
Spinal Surgery ◽  
Meta Analysis ◽  
Site Infection

A meta-analysis of spinal surgical site infection and vancomycin powder

2014 ◽  
Vol 21 (6) ◽  
pp. 974-983 ◽  
Author(s):  
Nickalus R. Khan ◽  
Clinton J. Thompson ◽  
Michael DeCuypere ◽  
Jonathan M. Angotti ◽  
Erick Kalobwe ◽  
...  
Keyword(s):  
Relative Risk ◽  
Surgical Site Infection ◽  
Risk Reduction ◽  
Spine Surgery ◽  
Spinal Surgery ◽  
Meta Analysis ◽  
Control Group ◽  
Number Needed To Treat ◽  
Site Infection ◽  
Vancomycin Powder

Object Surgical site infection (SSI) is a serious and costly complication of spinal surgery. There have been several conflicting reports on the use of intrawound vancomycin powder in decreasing SSI in spine surgery. The purpose of this study is to answer the question: “Does intrawound vancomycin powder reduce the rate of SSIs in spine surgery?” Methods A comprehensive search of multiple electronic databases and bibliographies was conducted to identify clinical studies that evaluated the rates of SSI with and without the use of intrawound vancomycin powder in spine surgery. Independent reviewers extracted data and graded the quality of each paper that met inclusion criteria. A random effects meta-analysis was then performed. Results The search identified 9 retrospective cohort studies (Level III evidence) and 1 randomized controlled trial (Level II evidence). There were 2574 cases and 106 infections in the control group (4.1%) and 2518 cases and 33 infections (1.3%) in the treatment group, yielding a pooled absolute risk reduction and relative risk reduction of 2.8% and 68%, respectively. The meta-analysis revealed the use of vancomycin powder to be protective in preventing SSI (relative risk = 0.34, 95% confidence interval 0.17–0.66, p = 0.021). The number needed to treat to prevent 1 SSI was 36. A subgroup analysis found that patients who had implants had a reduced risk of SSI with vancomycin powder (p = 0.023), compared with those who had noninstrumented spinal operations (p = 0.226). Conclusions This meta-analysis suggests that the use of vancomycin powder may be protective against SSI in open spinal surgery; however, the exact population in which it should be used is not clear. This benefit may be most appreciated in higher-risk populations or in facilities with a high baseline rate of infection.

Risk Factors for Surgical Site Infection After Spinal Surgery: A Systematic Review and Meta-Analysis Based on Twenty-Seven Studies

2019 ◽  
Vol 123 ◽  
pp. e318-e329 ◽  
Author(s):  
Xiao-Qiang Peng ◽  
Chun-Guang Sun ◽  
Zheng-Guo Fei ◽  
Qi-Jia Zhou
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Surgical Site Infection ◽  
Spinal Surgery ◽  
Meta Analysis ◽  
Site Infection

scholarly journals Preoperative Versus Extended Postoperative Antimicrobial Prophylaxis of Surgical Site Infection During Spinal Surgery: A Comprehensive Systematic Review and Meta-Analysis

2020 ◽  
Vol 37 (6) ◽  
pp. 2710-2733
Author(s):  
Blaine T. Phillips ◽  
Emma S. Sheldon ◽  
Vwaire Orhurhu ◽  
Robert A. Ravinsky ◽  
Monika E. Freiser ◽  
...  
Keyword(s):  
Systematic Review ◽  
Surgical Site Infection ◽  
Spinal Surgery ◽  
Antimicrobial Prophylaxis ◽  
Meta Analysis ◽  
Site Infection

Smoking and Risk of Surgical Site Infection after Spinal Surgery: A Systematic Review and Meta-Analysis

2017 ◽  
Vol 18 (2) ◽  
pp. 206-214 ◽  
Author(s):  
Lingde Kong ◽  
Zhao Liu ◽  
Fei Meng ◽  
Yong Shen
Keyword(s):  
Systematic Review ◽  
Surgical Site Infection ◽  
Spinal Surgery ◽  
Meta Analysis ◽  
Site Infection

Association of malnutrition with surgical site infection following spinal surgery: systematic review and meta-analysis

2020 ◽  
Vol 104 (1) ◽  
pp. 111-119 ◽  
Author(s):  
A.G. Tsantes ◽  
D.V. Papadopoulos ◽  
T. Lytras ◽  
A.E. Tsantes ◽  
A.F. Mavrogenis ◽  
...  
Keyword(s):  
Systematic Review ◽  
Surgical Site Infection ◽  
Spinal Surgery ◽  
Meta Analysis ◽  
Site Infection
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