Multidisciplinary approach to the treatment of invasive fungal infections in adult patients. Prophylaxis, empirical, preemptive or targeted therapy, which is the best in the different hosts?

A proper diagnostic strategy of invasive fungal infections (IFI) is a very important component in the management of infectious complications in hematological patients. A good diagnostic approach should be adapted to the patient in relation to the underlying disease, stage of disease, localization of infection and immune status. None of the diagnostic markers can be entirely adopted for medical decision making, and sometimes it’s useful to use the combination of several microbiological tests.The diagnosis of IFI must therefore have a multidisciplinary approach that includes clinical suspicion, microbiological results and radiological evidence.

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Echinocandins – in particular caspofungin for prevention and treatment of invasive fungal infections in adult patients with onco-hematological diseases including recipients of hematopoietic stem cells

Zakażenia XXI wieku ◽

10.31350/zakazenia/2018/4/z2018034 ◽

2018 ◽

Vol 2018 (4) ◽

pp. 183-191

Author(s):

Michał Górka ◽

Martyna Maciejewska ◽

Emilian Snarski ◽

Wiesław W Jędrzejczak

Keyword(s):

Stem Cells ◽

Hematopoietic Stem Cells ◽

Fungal Infections ◽

Invasive Fungal Infections ◽

Adult Patients ◽

Hematopoietic Stem ◽

Hematological Diseases ◽

Prevention And Treatment

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Faculty Opinions recommendation of Challenging recommended oral and intravenous voriconazole doses for improved efficacy and safety: population pharmacokinetics-based analysis of adult patients with invasive fungal infections.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.716397814.793458130 ◽

2012 ◽

Author(s):

John Baddley

Keyword(s):

Population Pharmacokinetics ◽

Fungal Infections ◽

Invasive Fungal Infections ◽

Adult Patients ◽

Efficacy And Safety ◽

Safety Population

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Diagnosis of invasive fungal infections

Reviews in Health Care ◽

10.7175/rhc.v3i1s.429 ◽

2012 ◽

Vol 3 (1S) ◽

pp. 15-25

Author(s):

Anna Maria Barbui ◽

Corrado Girmenia ◽

Giorgio Limerutti

Keyword(s):

Multidisciplinary Approach ◽

Medical Decision Making ◽

Immune Status ◽

Fungal Infections ◽

Underlying Disease ◽

Infectious Complications ◽

Invasive Fungal Infections ◽

Disease Stage ◽

Medical Decision ◽

Diagnostic Strategy

A proper diagnostic strategy of invasive fungal infections (IFI) is a very important component in the management of infectious complications in hematological patients. A good diagnostic approach should be adapted to the patient in relation to the underlying disease, stage of disease, localization of infection and immune status. None of the diagnostic markers can be entirely adopted for medical decision making, and sometimes it’s useful to use the combination of several microbiological tests.The diagnosis of IFI must therefore have a multidisciplinary approach that includes clinical suspicion, microbiological results and radiological evidence.

Download Full-text