scholarly journals Structural and biomechanical properties and trace elements composition of the corneoscleral eye shell in normal tension glaucoma

2021 ◽  
Vol 14 (3) ◽  
pp. 113-119
Author(s):  
L. L. Arutyunyan ◽  
E. N. Iomdina ◽  
Yu. S. Morozova ◽  
S. I. Anisimov ◽  
S. Yu. Anisimova
Keyword(s):  
Trace Elements ◽  
Intraocular Pressure ◽  
Biomechanical Properties ◽  
Normal Tension Glaucoma ◽  
Pressure Level ◽  
Collagen Biosynthesis ◽  
Eye Shell ◽  
Cross Links ◽  
Biomechanical Features ◽  
Intraocular Fluid

The results of comparative studies of the structural and biomechanical features of the corneoscleral eye shell in various clinical forms of glaucoma are presented. The article discusses how the systemic and local imbalance of trace elements that regulate collagen biosynthesis, the formation of cross-links in the connective tissue structures of the sclera, and the hydrodynamics of the intraocular fluid, affect the intraocular pressure level, and thereby the character of the development of glaucomatous lesions in normal tension glaucoma. Modern literature is shown to indicate the prospects for further research in this direction.

scholarly journals Travoprost with sofZia® preservative system lowered intraocular pressure of Japanese normal tension glaucoma with minimal side effects

2014 ◽  
pp. 347 ◽  
Author(s):  
Shiro Mizoue ◽  
Tadashi Nakano ◽  
Nobuo Fuse ◽  
Aiko Iwase ◽  
Shun Mastumoto ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Side Effects ◽  
Normal Tension Glaucoma

Intraocular pressure measured by dynamic contour tonometer and ocular response analyzer in normal tension glaucoma

2009 ◽  
Vol 248 (1) ◽  
pp. 73-77 ◽  
Author(s):  
Tetsuya Morita ◽  
Nobuyuki Shoji ◽  
Kazutaka Kamiya ◽  
Mana Hagishima ◽  
Fusako Fujimura ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Normal Tension Glaucoma ◽  
Ocular Response Analyzer ◽  
Dynamic Contour Tonometer

scholarly journals Surgery for normal tension glaucoma. Target intraocular pressure and visual field progression

2009 ◽  
Vol 75 (S224) ◽  
pp. 43-44 ◽  
Author(s):  
L. Fontana ◽  
A. C. Viswanathan ◽  
D. Poinooswamy ◽  
R. A. Hitchings ◽  
L. Scullica
Keyword(s):  
Intraocular Pressure ◽  
Visual Field ◽  
Normal Tension Glaucoma ◽  
Visual Field Progression

scholarly journals Novel Method of Measuring Corneal Viscoelasticity Using the Corvis ST Tonometer

2022 ◽  
Vol 11 (1) ◽  
pp. 261
Author(s):  
Agnieszka Boszczyk ◽  
Henryk Kasprzak ◽  
Joanna Przeździecka-Dołyk
Keyword(s):  
Intraocular Pressure ◽  
Viscoelastic Properties ◽  
High Speed ◽  
Central Area ◽  
Biomechanical Properties ◽  
P Value ◽  
Corvis St ◽  
Corneal Deformation ◽  
The Times ◽  
High Repeatability

Background: The process of rapid propagation of the corneal deformation in air puff tonometer depends not only on intraocular pressure, but also on the biomechanical properties of the cornea and anterior eye. One of the biomechanical properties of the cornea is viscoelasticity, which is the most visible in its high-speed deformations. It seems reasonable to link the corneal viscoelasticity parameter to two moments of the highest speed of corneal deformations, when the cornea buckles. The aim of this work is to present a method of determining the time and place of occurrence of corneal buckling, examine spatial and temporal dependencies between two corneal applanations and bucklings in the Corvis ST tonometer, and correlate these dependencies with corneal viscoelastic properties. Methods: Images of the horizontal cross section of the Corvis ST deformed cornea from the air puff tonometer Corvis ST were used. 14 volunteers participated in the study, each of them had one eye measured eight times. Mutual changes in the profile slopes of the deformed corneas were numerically determined. They describe pure corneal deformation, eliminating the influence of rotation, and displacement of the entire eyeball. For each point in the central area of the corneal profile, the maximum velocities of mutual slope changes accompanying the applanations were estimated. The times of their occurrence were adopted as buckling times. Results: The propagation of buckling along the corneal profile is presented, as well as the repeatability and mutual correlations between the buckling parameters and intraocular pressure. Based on the relationship between them, a new parameter describing corneal hysteresis: Corvis Viscoelasticity (CVE) is introduced. It is characterized by high repeatability: ICC = 0.82 (0.69–0.93 CI) and low and insignificant correlation with intraocular pressure: r = 0.25 (p-value = 0.38). Conclusion: The results show for the first time how to measure the corneal buckling and viscoelastic effects with Corvis ST. CVE is a new proposed biomechanical parameter related to the viscoelastic properties of the cornea, which has high repeatability for the examined subject. The distribution of its values is planned to be tested on different groups of patients in order to investigate its clinical applicability.

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