scholarly journals ROLE OF 3D DIGITAL MAMMOGRAPHY IN STUDYING BREAST LESIONS IN ADULT FEMALES OF DENSE BREAST

2021 ◽  
Vol 50 (4) ◽  
pp. 3101-3116
2021 ◽  
Vol 20 (1) ◽  
pp. 59-64
Author(s):  
Sujata Panta ◽  
Rajive Raj Shahi ◽  
Sujit Panta ◽  
Bina Basnet ◽  
Kalpana Rai ◽  
...  

Introduction: Mammography is a simple and effective tool in early detection of breast lesions. However its sensitivity is less in dense breast. The aim of the study is to see whether addition of ultrasonography adds on to the diagnostic value by finding more breast lesions in evaluation of mammographic dense breasts or not. Methods: The hospital data of all the patients who underwent mammography in the Department of Radiology of Shree Birendra Hospital, Kathmandu over a period of two and a half years from November 2017 to April 2020 were retrieved and retrospectively analyzed. The mammographic findings of patients with dense breast were compared with the corroborative ultrasonographic findings. Discrepancy in positive findings between the two imaging modalities was studied.    Results: Out of 536 patients studied, 238 patients had mammographic dense breast. Comparative study showed 82 cases with positive findings on mammography alone, compared to 114 cases with positive findings on combined mammography and ultrasonography with p-value < 0.05 which is statistically significant. Conclusions: Ultrasonography is a useful additional imaging modality in evaluation of mammographic dense breast by finding more breast lesions compared to Mammography alone.


2020 ◽  
Vol 71 (1) ◽  
pp. 129-136
Author(s):  
Rabab Abdelmoniem ◽  
Fatma Mohamed ◽  
Samer Botros ◽  
Amr Abd Elsamad

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
A M Elshibiny ◽  
M E Abdelrahman ◽  
L M Abdelrahman

Abstract Background Digital Breast Tomosythesis is a new technology of digital mammography that enables the acquisition of three dimensional volume of thin section data, and thus reduces or eliminates tissue overlap especially in dense breast, such ability allow visualization of cancers not apparent by digital mammography and differentiate between benign and malignant lesion. Objectives to compare the efficacy of digital breast Tomosynthesis (BDT) to digital Mammography (DM) in diagnosis of different breast lesions in dense breast. Patients and Method in this prospective study 30 patients with breast density ACR/C and ACR/D were assessed by Digital Mammography and Digital Breast Tomsynthesis. Each lesion was assigned a blinded category in an individual performance for each modality. The resultant BI-RADS categories were correlated with report of the pathology specimens or outcome follow up. Results Both modalities were compared regarding characterization, using Chi Square test (p value:0.035).The sensitivity, specificity and accuracy of digital mammography was 62.5%, 68.75% and 66% have significantly increase with tomosynthesis to be 100%,91% and 97% respectively. Conclusion Digital breast tomosythesis significantly enhanced characterization of breast lesions than digital mammography in dense breast parenchyma (ACR/C and ACR/D).


2021 ◽  
Vol 9 (6) ◽  
pp. 1242
Author(s):  
Loganathan Ponnusamy ◽  
Haley Sutton ◽  
Robert D. Mitchell ◽  
Daniel E. Sonenshine ◽  
Charles S. Apperson ◽  
...  

The transovarial transmission of tick-borne bacterial pathogens is an important mechanism for their maintenance in natural populations and transmission, causing disease in humans and animals. The mechanism for this transmission and the possible role of tick hormones facilitating this process have never been studied. Injections of physiological levels of the tick hormone, 20-hydroxyecdysone (20E), into part-fed (virgin) adult females of the American dog tick, Dermacentor variabilis, attached to the host caused a reduction in density of Rickettsia montanensis in the carcass and an increase in the ovaries compared to buffer-injected controls. This injection initiates yolk protein synthesis and uptake by the eggs but has no effect on blood feeding. Francisella sp. and R. montanensis were the predominant bacteria based on the proportionality in the carcass and ovary. The total bacteria load increased in the carcass and ovaries, and bacteria in the genus Pseudomonas increased in the carcass after the 20E injection. The mechanism of how the Rickettsia species respond to changes in tick hormonal regulation needs further investigation. Multiple possible mechanisms for the proliferation of R. montanensis in the ovaries are proposed.


Pathology ◽  
2009 ◽  
Vol 41 (1) ◽  
pp. 68-76 ◽  
Author(s):  
Takuya Moriya ◽  
Yuji Kozuka ◽  
Naoki Kanomata ◽  
Gary M. Tse ◽  
Puay-Hoon Tan

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