scholarly journals Role of Tomosynthesis with correlation to 2D Mammography in characterization of breast lesions in dense breast

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
A M Elshibiny ◽  
M E Abdelrahman ◽  
L M Abdelrahman
Keyword(s):  
Digital Mammography ◽  
New Technology ◽  
Malignant Lesion ◽  
Three Dimensional ◽  
Digital Breast Tomosynthesis ◽  
Individual Performance ◽  
Dense Breast ◽  
P Value ◽  
Breast Lesions

Abstract Background Digital Breast Tomosythesis is a new technology of digital mammography that enables the acquisition of three dimensional volume of thin section data, and thus reduces or eliminates tissue overlap especially in dense breast, such ability allow visualization of cancers not apparent by digital mammography and differentiate between benign and malignant lesion. Objectives to compare the efficacy of digital breast Tomosynthesis (BDT) to digital Mammography (DM) in diagnosis of different breast lesions in dense breast. Patients and Method in this prospective study 30 patients with breast density ACR/C and ACR/D were assessed by Digital Mammography and Digital Breast Tomsynthesis. Each lesion was assigned a blinded category in an individual performance for each modality. The resultant BI-RADS categories were correlated with report of the pathology specimens or outcome follow up. Results Both modalities were compared regarding characterization, using Chi Square test (p value:0.035).The sensitivity, specificity and accuracy of digital mammography was 62.5%, 68.75% and 66% have significantly increase with tomosynthesis to be 100%,91% and 97% respectively. Conclusion Digital breast tomosythesis significantly enhanced characterization of breast lesions than digital mammography in dense breast parenchyma (ACR/C and ACR/D).

scholarly journals Three-dimensional tomosynthesis versus two-dimensional mammography in detection and characterization of different breast lesions

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Samia Aboelnour Abdeltwab Abdelattef ◽  
Suzan Farouk Ibrahim ◽  
Wafaa Raft Abdelhamid ◽  
Fatten Mohamed Mahmoud
Keyword(s):  
Breast Cancer ◽  
Three Dimensional ◽  
Digital Breast Tomosynthesis ◽  
Final Diagnosis ◽  
Recall Rate ◽  
Architectural Distortion ◽  
Breast Lesions ◽  
Predictive Values ◽  
Sensitivity Specificity

Abstract Background Breast cancer is considered the most serious lesion among different breast lesions. Mammography is the corner stone for screening for detection of breast cancer. It has been modified to digital mammography (DM) and then to digital breast tomosynthesis (DBT). Tomosynthesis is an emerging technique for diagnosis and screening of breast lesions. The aim of this study is to interrogate whether the addition of DBT to DM helps in better detection and characterization of different breast lesions. Methods This is a prospective study carried on 38 female patients according to our inclusion criteria. All patients were evaluated by using DM alone and thereafter with the addition of DBT to DM. Recall rate was calculated, and the imaging findings of each case were correlated with the final diagnosis and follow-up. Results DM identified 32 lesions while DBT with DM identified 37 lesions. On DM alone, 17 lesions were characterized as masses, 5 as focal asymmetry, 2 as architectural distortion, 7 as microcalcification and 1 as macrocalcification. With the addition of DBT, 27 lesions were characterized as masses, 1 as focal asymmetry, 1 as architectural distortion, 7 as microcalcification and 1 as macrocalcification. So, there were better detection and characterization of lesions with the addition of DBT than DM alone. The sensitivity, specificity, AUC, positive and negative predictive values were significantly higher with the addition of DBT to DM (100%, 90.5%, 0.952, 90% and 100%, respectively) than with DM (77.8%, 80.9%, 0.794, 77.8% and 80.9%, respectively) for all breast lesions. Conclusions The addition of DBT to DM helps in better detection and characterization of different breast lesions. This leads to early detection of breast cancer, improvement of the performance of radiologists and saving time by reduction of recall rate.

Dense Breast Ultrasound Screening After Digital Mammography Versus After Digital Breast Tomosynthesis

2019 ◽  
Vol 213 (6) ◽  
pp. 1397-1402 ◽  
Author(s):  
Elizabeth H. Dibble ◽  
Tisha M. Singer ◽  
Nneka Jimoh ◽  
Grayson L. Baird ◽  
Ana P. Lourenco
Keyword(s):  
Digital Mammography ◽  
Digital Breast Tomosynthesis ◽  
Breast Ultrasound ◽  
Dense Breast ◽  
Ultrasound Screening ◽  
Breast Tomosynthesis

scholarly journals Characterization of Breast Lesions: Comparison between Three-dimensional Ultrasound and Automated Volume Breast Ultrasound

2021 ◽  
Vol 5 (3) ◽  
pp. 204
Author(s):  
Jia, MD Wanru ◽  
Zhang, MD Jingwen, ◽  
Dong, MD Yijie ◽  
Zhu, MD Ying ◽  
Jia, MD Xiaohong ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Breast Ultrasound ◽  
Breast Lesions

scholarly journals Diagnostic accuracy of digital breast tomosynthesis in combination with 2D mammography for the characterisation of mammographic abnormalities

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Vithya Visalatchi Sanmugasiva ◽  
Marlina Tanty Ramli Hamid ◽  
Farhana Fadzli ◽  
Faizatul Izza Rozalli ◽  
Chai Hong Yeong ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Breast Imaging ◽  
Digital Breast Tomosynthesis ◽  
Asian Population ◽  
Architectural Distortion ◽  
Breast Lesions ◽  
Cross Sectional ◽  
Breast Tomosynthesis ◽  
Full Field

AbstractThis study aims to assess the diagnostic accuracy of digital breast tomosynthesis in combination with full field digital mammography (DBT + FFDM) in the charaterisation of Breast Imaging-reporting and Data System (BI-RADS) category 3, 4 and 5 lesions. Retrospective cross-sectional study of 390 patients with BI-RADS 3, 4 and 5 mammography with available histopathology examination results were recruited from in a single center of a multi-ethnic Asian population. 2 readers independently reported the FFDM and DBT images and classified lesions detected (mass, calcifications, asymmetric density and architectural distortion) based on American College of Radiology-BI-RADS lexicon. Of the 390 patients recruited, 182 malignancies were reported. Positive predictive value (PPV) of cancer was 46.7%. The PPV in BI-RADS 4a, 4b, 4c and 5 were 6.0%, 38.3%, 68.9%, and 93.1%, respectively. Among all the cancers, 76% presented as masses, 4% as calcifications and 20% as asymmetry. An additional of 4% of cancers were detected on ultrasound. The sensitivity, specificity, PPV and NPV of mass lesions detected on DBT + FFDM were 93.8%, 85.1%, 88.8% and 91.5%, respectively. The PPV for calcification is 61.6% and asymmetry is 60.7%. 81.6% of cancer detected were invasive and 13.3% were in-situ type. Our study showed that DBT is proven to be an effective tool in the diagnosis and characterization of breast lesions and supports the current body of literature that states that integrating DBT to FFDM allows good characterization of breast lesions and accurate diagnosis of cancer.

Dynamic three-dimensional imaging with partial k-space sampling: initial application for gadolinium-enhanced rate characterization of breast lesions.

Radiology ◽  
1995 ◽  
Vol 196 (1) ◽  
pp. 135-142 ◽  
Author(s):  
T L Chenevert ◽  
M A Helvie ◽  
A M Aisen ◽  
I R Francis ◽  
D D Adler ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Breast Lesions ◽  
Three Dimensional Imaging ◽  
Initial Application

scholarly journals Comparing the diagnostic efficacy of digital breast tomosynthesis with full-field digital mammography using BI-RADS scoring

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Rana M. Naeim ◽  
Rania A. Marouf ◽  
Merhan A. Nasr ◽  
Marwa E. Abd El-Rahman
Keyword(s):  
Breast Cancer ◽  
Diagnostic Accuracy ◽  
Digital Mammography ◽  
Digital Breast Tomosynthesis ◽  
Breast Lesions ◽  
Breast Tomosynthesis ◽  
Full Field ◽  
Dense Breasts ◽  
Full Field Digital Mammography ◽  
Diagnostic Indices

Abstract Background Mammography has been the mainstay for the detection of breast cancer over decades. It has gradually advanced from screen film to full-field digital mammography. Tomosynthesis has evolved as advanced imaging for early diagnosis of breast lesions with a promising role in both diagnostic and screening settings, particularly in dense and treated breasts. Results This study included 90 female patients according to our inclusion criteria. All patients perform full-field digital mammography (FFDM) and digital breast tomosynthesis (DBT) and were classified according to breast density and age groups. Breast imaging reporting and data system (BI-RADS) scoring was assigned for each case. This was correlated with the final diagnosis; the diagnostic indices of mammography were a sensitivity of 64.44%, a specificity of 77.78%, a positive predictive value (PPV) 74.63%, a negative predictive value (NPV) of 68.63%, and a diagnostic accuracy of 71.11%. Diagnostic indices of DBT were a sensitivity of 100%, a specificity of 97.77%, PPV 97.78%, NPV 100%, and diagnostic accuracy of 97.7%. In patients with dense breasts American College of Radiology (ACR) (c and d), 61% of cases had changed their BIRADS scoring with the addition of tomosynthesis. Yet, in non-dense breast ACR (a and b), 45% of cases had changed BIRADS scoring with the addition of DBT to FFDM. Conclusion DBT is a promising imaging modality offering better detection and characterization of different breast abnormalities, especially in young females, and those with dense breasts with an increase of sensitivity and specificity than FFDM. This leads to a reduction in the recalled cases, negative biopsies, and assessing the efficacy of therapy as it enables improving detection of breast cancer and different breast lesions not visualized by conventional mammography

scholarly journals One view or two views for wide-angle tomosynthesis with synthetic mammography in the assessment setting?

2021 ◽  
Author(s):  
Paola Clauser ◽  
Pascal A. T. Baltzer ◽  
Panagiotis Kapetas ◽  
Ramona Woitek ◽  
Michael Weber ◽  
...  
Keyword(s):  
Digital Mammography ◽  
Detection Rate ◽  
Diagnostic Performance ◽  
Digital Breast Tomosynthesis ◽  
Rate Sensitivity ◽  
Breast Lesions ◽  
Wide Angle ◽  
Breast Tomosynthesis ◽  
Lesion Type ◽  
Sensitivity Specificity

Abstract Objectives To evaluate the diagnostic performance in the assessment setting of three protocols: one-view wide-angle digital breast tomosynthesis (WA-DBT) with synthetic mammography (SM), two-view WA-DBT/SM, and two-view digital mammography (DM). Methods Included in this retrospective study were patients who underwent bilateral two-view DM and WA-DBT. SM were reconstructed from the WA-DBT data. The standard of reference was histology and/or 2 years follow-up. Included were 205 women with 179 lesions (89 malignant, 90 benign). Four blinded readers randomly evaluated images to assess density, lesion type, and level of suspicion according to BI-RADS. Three protocols were evaluated: two-view DM, one-view (mediolateral oblique) WA-DBT/SM, and two-view WA-DBT/SM. Detection rate, sensitivity, specificity, and accuracy were calculated and compared using multivariate analysis. Reading time was assessed. Results The detection rate was higher with two-view WA-DBT/SM (p = 0.063). Sensitivity was higher for two-view WA-DBT/SM compared to two-view DM (p = 0.001) and one-view WA-DBT/SM (p = 0.058). No significant differences in specificity were found. Accuracy was higher with both one-view WA-DBT/SM and two-view WA-DBT/SM compared to DM (p = 0.003 and > 0.001, respectively). Accuracy did not differ between one- and two-view WA-DBT/SM. Two-view WA-DBT/SM performed better for masses and asymmetries. Reading times were significantly longer when WA-DBT was evaluated. Conclusions One-view and two-view WA-DBT/SM can achieve a higher diagnostic performance compared to two-view DM. The detection rate and sensitivity were highest with two-view WA-DBT/SM. Two-view WA-DBT/SM appears to be the most appropriate tool for the assessment of breast lesions. Key Points • Detection rate with two-view wide-angle digital breast tomosynthesis (WA-DBT) is significantly higher than with two-view digital mammography in the assessment setting. • Diagnostic accuracy of one-view and two-view WA-DBT with synthetic mammography (SM) in the assessment setting is higher than that of two-view digital mammography. • Compared to one-view WA-DBT with SM, two-view WA-DBT with SM seems to be the most appropriate tool for the assessment of breast lesions.

scholarly journals Simultaneous Particle Tracking and Temperature Measurements during Additive Manufacturing using a High-speed Spectral Plenoptic Camera

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Dustin Kelly ◽  
Ralf Fischer ◽  
Ari Goldman ◽  
Sarah Morris ◽  
Bart Prorok ◽  
...  
Keyword(s):  
Additive Manufacturing ◽  
Particle Tracking ◽  
Automotive Industry ◽  
High Speed ◽  
New Technology ◽  
Three Dimensional ◽  
Melt Pool ◽  
Plenoptic Camera ◽  
Metal Additive

In this work, a high-speed spectral plenoptic camera was used for three-dimensional (3D) simultaneous particle tracking and pyrometry measurements of hot spatter particles ejected during the metal additive manufacturing process. Additive manufacturing (AM) has an increasing role in the aerospace, energy, medical and automotive industry (DebRoy et al., 2018). While this new technology enables the production of highly advanced parts, research on the fundamental mechanisms governing the laser-matter interactions are an ongoing challenge because of the spatial and temporal resolution inherent to the AM process. One challenge is the characterization of spatter particles ejected from the melt pool, as these particles can be incorporated into the final part affecting the mechanical properties (Deng et al., 2020). One potential solution for simultaneously measuring velocity and temperature of the spatter particles is the spectral plenoptic camera.

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