PARASITOLOGICAL AND BIOCHEMICAL STUDIES ON CATTLE THEILERIOSIS IN ISMAILIA GOVERNORATE WITH SPECIAL REFERENCE TO ITS CONTROL

Electrophoretic analyses are presented for 79 specimens of blood plasma or serum from 42 rheumatic subjects during apparent health, following respiratory illness, and during rheumatic fever. Electrophoretic studies revealed a prolonged elevation in the gamma component for a period varying from weeks to months following an antecedent respiratory illness with or without the development of rheumatic fever. During acute rheumatic fever, the gamma globulin component was normal in the absence of antecedent illness. Elevation of the gamma globulin component in rheumatic fever is not a function of the rheumatic process. The alpha globulin components were usually elevated during febrile periods. No evidence was obtained in these studies that the immune response of rheumatic subjects to infections presumably streptococcal in origin differed from that of nonrheumatic individuals.

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IMMUNOLOGIC AND BIOCHEMICAL STUDIES IN INFANTS AND CHILDREN, WITH SPECIAL REFERENCE TO RHEUMATIC FEVER

PEDIATRICS ◽

10.1542/peds.2.4.410 ◽

1948 ◽

Vol 2 (4) ◽

pp. 410-414

Author(s):

PAUL F. DEGARA

Keyword(s):

Rheumatic Fever ◽

Special Reference ◽

High Titer ◽

Infants And Children ◽

Significant Difference ◽

Biochemical Studies ◽

History Of ◽

Group A ◽

Different Strains ◽

In Infants And Children

Agglutinative antibodies for three different strains Str. hemolyticus, beta, group A, were studied in 497 sera from 372 children. A high titer was found in approximately 9% of well children. There was no significant difference between rheumatic and non-rheumatic subjects in the incidence of high agglutinin titers for Str. hemolyticus. Following infections, presumably streptococcal in origin, approximately 46% of the children examined had high agglutinin titers for Str. hemolyticus. In active rheumatic fever, agglutinins were present in high titers in nine out of 11 patients who had experienced an antecedent illness, presumably streptococcal in origin. Of 23 patients with no history of such an infection, only three had streptococcal agglutinins.

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IMMUNOLOGIC AND BIOCHEMICAL STUDIES IN INFANTS AND CHILDREN WITH SPECIAL REFERENCE TO RHEUMATIC FEVER

PEDIATRICS ◽

10.1542/peds.2.3.248 ◽

1948 ◽

Vol 2 (3) ◽

pp. 248-254

Author(s):

PAUL F. DEGARA ◽

HENRY P. GOLDBERG

Keyword(s):

Rheumatic Fever ◽

Special Reference ◽

Infants And Children ◽

Normal Children ◽

Complement Activity ◽

Intercurrent Illness ◽

Biochemical Studies ◽

Hereditary Susceptibility ◽

In Infants And Children

Complement activity of 421 sera from 330 children was determined. Complement activity was not influenced by antecedent illness. Low complement titers were found in approximately 25% of 75 normal children during intercurrent illness. Approximately 25% of 29 patients with active rheumatic fever had low complement titers. No evidence was obtained to indicate that complement activity is a factor in hereditary susceptibility to rheumatic fever.

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