scholarly journals Quality of Life of Chronic Hepatitis C Patients Receiving Sovaldi Treatment Regimen at Sharq Almadina Hospital in Alexandria

2022 ◽  
Vol 25 (1) ◽  
pp. 42-56
Author(s):  
Nahla Gamaleldin ◽  
Nagwa Shokeir ◽  
Hend Abdelaziz ◽  
Heba Elweshahy
Keyword(s):  
Quality Of Life ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Treatment Regimen ◽  
Chronic Hepatitis C Patients

scholarly journals Assessment of health-related quality of life in antiviral-treated Taiwanese chronic hepatitis C patients using SF-36 and CLDQ

2014 ◽  
Vol 12 (1) ◽  
pp. 97 ◽  
Author(s):  
Shu-Chuan Chang ◽  
Sheng-Shun Yang ◽  
Chiu-Chun Chang ◽  
Chun-Che Lin ◽  
Yueh-Chin Chung ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Health Related Quality ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
Chronic Hepatitis C Patients

scholarly journals Quality of life in patients with chronic hepatitis C

2011 ◽  
Vol 139 (3-4) ◽  
pp. 165-169
Author(s):  
Sladjana Pavic ◽  
Dragan Delic ◽  
Jasmina Simonovic ◽  
Neda Svirtlih
Keyword(s):  
Quality Of Life ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Liver Diseases ◽  
Chronic Liver ◽  
Healthy Population ◽  
Chronic Liver Diseases ◽  
Chronic Hepatitis C Patients

Introduction. Hepatitis C virus often causes chronic liver disease reducing physical, mental and social functions in these patients. Objective. The aim of this investigation was analysis of the quality of life in chronic hepatitis C patients compared to patients with other chronic liver diseases and healthy population, as well as investigation of the influence of socio-demographic factors on the quality of life in patients with chronic hepatitis C. Methods. A generic Short Form-36 (SF-36) questionnaire and Chronic Liver Diseases Questionnaire (CLDQ) were used in this prospective study for the investigation of the quality of life in 160 patients (100 patients with chronic hepatitis C, 30 patients with chronic hepatitis B, 30 patients with non-viral chronic liver diseases) and 50 healthy controls. Results. Reduced quality of life was noted in patients with chronic hepatitis C patients in comparison with healthy controls (p=0.00). Significant differences in SF-36 were found between patients with chronic hepatitis C and B regarding physical functions, activity, physical pain and emotional functions. Multivariate linear regression analysis revealed ages below 50 years as the most important positive variable in chronic hepatitis C patients for total score of the quality of life and physical component score (B=14.5; SE=5.16; p=0.049; and B=16.4; SE=5.94; p=0.003, respectively). The most important positive variable for the mental component of the quality of life was male gender (B=15.3; SE=5.81; p=0.003). Conclusion. Quality of life is reduced in patients with chronic hepatitis C in comparison with healthy population. The quality of life in chronic hepatitis C patients is better than in patients with other non-viral chronic liver diseases. In comparison with patients with chronic hepatitis B, reduction in some domains of the quality of life is noted. Younger age is the most predictable group for the lowest damage of the total quality of life in patients with chronic hepatitis C patients among other socio- demographic characteristics of these patients.

scholarly journals Health Related Quality of Life in Chronic Hepatitis C Patients before and after treatment

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
H Abdelaziz ◽  
S Seifeldin ◽  
M Elhosseiny ◽  
A Abolfotouh
Keyword(s):  
Quality Of Life ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Viral Therapy ◽  
End Of Treatment ◽  
Related Quality ◽  
Health Related ◽  
Chronic Hepatitis C Patients

Abstract Back ground Chronic hepatitis C (CHC) virus infection is a major cause of chronic liver disease and death throughout the world; several studies have shown an impaired health-related quality of life (HRQoL)in patients with CHC compared to general population whereas treatment of this disease often produce varying degrees of adverse effects which may negatively affect a patient’s HRQoL. Aim To measure the change in the HRQoL of the patients after the treatment and compare this change with response to treatment. Methodology 427 chronic HCV newly recruited patients to receive pegylated interferon and ribavirin for 48 weeks in the National Hepatology & Tropical medicine Research Institute were selected and completed the SF-36 quality of life questionnaire before treatment and at the end of treatment then followed up for another six months to determine sustained virological response (SVR). Results Patients’ HRQoL showed deterioration in all domains at the end of treatment compared to baseline measures with high statistical significant differences (p < 0.001). Non-responders showed more deterioration than patients with SVR especially in the perception of “mental health, social wellbeing, bodily pain, and general health”. Conclusion Sustained virological response rate between chronic hepatitis C patients receiving combined anti-viral therapy (interferon and ribavirin) was 63.5%. HRQoL of patients receiving combined anti-viral therapy (interferon and ribavirin) deteriorated during the course of treatment till the end of treatment. Patients with SVR were less deteriorated than non-responders.

Depression and health related quality of life in chronic hepatitis c patients: A longitudinal study

2010 ◽  
Vol 122 ◽  
pp. S65
Author(s):  
R. Martín-Santos⁎ ◽  
R. Navinés ◽  
P. Castellví ◽  
E. Gómez-Gil ◽  
M. Valdés ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Hepatitis ◽  
Longitudinal Study ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Chronic Hepatitis C Patients

scholarly journals Health-Related Quality Of Life In Chronic Hepatitis C Patients With Depression

2014 ◽  
Vol 17 (3) ◽  
pp. A141-A142
Author(s):  
S. Sansgiry ◽  
J. Pyne ◽  
D. Smith ◽  
A.C. Brown ◽  
D. Hodges ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Chronic Hepatitis C Patients

scholarly journals Repercussions of chronic hepatitis C treatment

2018 ◽  
Vol 12 (03) ◽  
pp. 183-189
Author(s):  
Daniela Maria Falcão Oliveira ◽  
Juliano Souza Caliari ◽  
Ana Angélica Lima Dias ◽  
Rosely Moralez Figueiredo
Keyword(s):  
Quality Of Life ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Satisfactory Outcome ◽  
Research Interviews ◽  
And Coping ◽  
Theoretical Saturation ◽  
Chronic Hepatitis C Patients

Introduction: Individuals living with hepatitis C experience a series of changes in their lives, caused by either the disease itself or its treatment or both. In this sense, living with a chronic disease such as hepatitis C implies that patients must change their lifestyles, which requires that they rethink their habits in light of the new reality. To comprehend chronic hepatitis C patients’ perceptions, meanings, and quality-of-life effects. Methodology: Qualitative research; interviews with 12 patients at a specialized outpatient clinic from February to July 2012. The cohort size was determined by theoretical saturation and the interviews were analyzed by means of content analysis. Results: Data were organized into four categories: on medication, referenced fears, impact on sexuality, and coping with the new reality. The categorized data were discussed around the following themes: “Becoming sick” due to treatment and perceived aspects and Undergoing treatment and how to cope with it. Conclusion: Patients’ everyday lives and quality of life in general are affected especially by adverse side effects of hepatitis C medication and an assortment of feelings and uncertainties about the disease prognosis. Notwithstanding, most patients manage to find ways to cope with the treatment and complete it expecting a satisfactory outcome.

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