scholarly journals Remote magnetic navigation for heart rhythm disturbances treatment in patients after surgical correction of congenital heart disease

2021 ◽  
Vol 25 (1) ◽  
pp. 32
Author(s):  
V. V. Beloborodov ◽  
N. A. Elemesov ◽  
A. V. Ponomarenko ◽  
E. A. Morzhanaev ◽  
A. G. Filippenko ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Conflict Of Interest ◽  
Congenital Heart ◽  
Heart Diseases ◽  
Heart Rhythm ◽  
Surgical Correction ◽  
Published Data ◽  
Magnetic Navigation ◽  
Remote Magnetic Navigation

<p>The prevalence of congenital heart diseases is nine persons per 1000. Sometimes, congenital heart disease needs surgical correction. The long-term postoperative period is often associated with complex heart rhythm disturbances like ectopic or re-entry tachycardia. These cases, in combination with difficult anatomy, results in challenges during interventional treatment. Catheter ablation has been demonstrated as safe and effective in different types of arrhythmia treatments in such patients, including paediatric cohorts. Despite these facts, several important problems regarding using current technologies are still unresolved. Remote magnetic navigation showed good results regarding localisation of arrhythmogenic zones during treatment of complex heart rhythm disturbances. The objective of the present article is to review recently published data in this area and experience of Meshalkin National Medical Research Center in heart rhythm disturbances treatment using remote magnetic navigation in patients after surgical correction of congenital heart disease.</p><p>Received 28 September 2020. Revised 25 December 2020 г. Accepted 30 December 2020.</p><p><strong>Funding:</strong> The study did not have sponsorship.</p><p><strong>Conflict of interest:</strong> Authors declare no conflict of interest.</p><p><strong>Author contributions</strong><br />Conception and study design: A.B. Romanov, A.M. Chernyavskiy<br />Drafting the article: V.V. Beloborodov, А.V. Ponomarenko, E.А. Morzhanaev<br />Critical revision of the article: A.B. Romanov, А.V. Ponomarenko, I.L. Mikheenko, E.А. Morzhanaev, A.G. Filippenko, <br />A.M. Chernyavskiy<br />Final approval of the version to be published: V.V. Beloborodov, N.А. Yelemessov, А.V. Ponomarenko, E.А. Morzhanaev, <br />A.G. Filippenko, I.L. Mikheenko, A.M. Chernyavskiy, A.B. Romanov</p>

scholarly journals Down’s Syndrome with Congenital Heart Disease: Our Surgical Experience

2020 ◽  
Vol 13 (1) ◽  
pp. 35-39
Author(s):  
Md Zahidul Islam ◽  
Sakila Israt Jahan ◽  
Shahriar Moinuddin ◽  
Khondokar Shamim Shahriar Ziban Rushel ◽  
Shafiqul Islam ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Pulmonary Hypertension ◽  
Cardiac Surgery ◽  
Heart Disease ◽  
Congenital Heart ◽  
Heart Diseases ◽  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Surgical Correction ◽  
Pace Maker

Background: Our objective was to analyze the outcome of patients of Down’s syndrome with congenital heart diseases undergoing cardiac surgery. Methods: This was a retrospective study conducted between January 2013 and June 2019. 49 consecutive patients with Down’s syndrome with congenital heart disease admitted in pediatric cardiac surgery unit at National Institute of Cardiovascular Diseases (NICVD). Patients were followed up postoperatively for in-hospital outcome. Results: Among 49 patients the heart lesion ranked in incidence as follows- VSD 24(48.97%), AV canal defect 12(24.48%), TOF 6(12.24%), PDA 6(12.24%) and ASD 1(2.04%). Pulmonary hypertension was found in 63.25% patients. Moderate pulmonary hypertension was most common, found in 18(38.66%) patients. Severe and mild pulmonary hypertension was found in 10(32.38%) and 3(9.67%) patients respectively. All the patients had undergone surgical correction. The postoperative period was complicated in 44.89% of patients. The most frequent complication was pulmonary infection 20.40%, Wound infection 6.12% and low output syndrome 6.12% were the next. One patient had postoperative heart block, needed permanent pace maker implantation. In-hospital mortality was 12.24%. Conclusion: Patients with Down’s syndrome with congenital heart disease undergoing surgical correction had an acceptable postoperative morbidities and mortality. Cardiovasc. j. 2020; 13(1): 35-39

Acute and Long-Term Outcomes of Catheter Ablation Using Remote Magnetic Navigation in Patients With Congenital Heart Disease

2012 ◽  
Vol 110 (3) ◽  
pp. 409-414 ◽  
Author(s):  
Ferdi Akca ◽  
Tamas Bauernfeind ◽  
Maarten Witsenburg ◽  
Lara Dabiri Abkenari ◽  
Judith A. Cuypers ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Catheter Ablation ◽  
Congenital Heart ◽  
Magnetic Navigation ◽  
Long Term Outcomes ◽  
Remote Magnetic Navigation

scholarly journals Treatment of symptomatic atrial tachycardia in complex anatomic conditions: use and outcome of ablation in patients after damus-kaye-stansel surgery

EP Europace ◽  
2021 ◽  
Vol 23 (Supplement_3) ◽  
Author(s):  
AJ Fischer ◽  
SY Ho ◽  
S Ernst
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Aortic Valve ◽  
Congenital Heart ◽  
Three Dimensional ◽  
Magnetic Navigation ◽  
Image Integration ◽  
Ventricular Ejection Fraction ◽  
Remote Magnetic Navigation ◽  
Dimensional Image

Abstract Funding Acknowledgements Type of funding sources: None. Background Atrial tachycardias (AT) are amongst the most frequent complications in adult patients with congenital heart disease (ACHD). Their incidence mainly depends on age and complexity of underlying defect. AT has a marked impact on morbidity and mortality and is associated with sudden cardiac death particularly in complex ACHD patients. The arrhythmic substrate can be variable from re-entry to multifocal resulting in demanding requirements for electrophysiologic ablation procedures (EP) and thus, relatively high rates of recurrence. Methods and results Retrospective analysis of ACHD patients with prior Damus-Kaye-Stansel (DKS) surgery treated at one of the largest specialized tertiary centers for ACHD patients worldwide. Analysis focussed on occurrence of AT, respective treatment and outcome of EP. Over a median observation time of 15 years, 13 patients with prior DKS surgery and complex congenital heart defects of different types but uniformly Fontan circulation, were identified (median age 22.0 years (IQR 20.5 – 25.5), 76.9% male, 92.3% NYHA Class I, median systemic ventricular ejection fraction 58.5%, 69.2% extracardiac tunnel). Seven patients (53.8%) presented with symptomatic AT (median cyclic length 440 ms (IQR 360.0 – 517.5)). Of these, six patients underwent EP. Median procedure time was 180.5 min (IQR 160.8 – 274.5), median fluoroscopy time 1.56 min (IQR 0.51 – 4.73) and radiofrequency time 851 sec (265.0 -2005.0). Remote magnetic navigation was used to access ablation site through a retrograde access via the aortic as well as the neo-aortic valve.  Three-dimensional image integration aided in mapping and ablation. Throughout the procedure as well as in follow-up visits, no reportable complications were observed. After a mean of 1.5 procedures, all analysed patients stayed complaint-free throughout a median time-interval of 13 months. Conclusion AT are frequent in complex univentricular situations after Damus-Kaye-Stansel surgery (53.8%). Although more than one procedure (mean 1.5) was necessary to achieve satisfactory results even in experienced hands, EP appears to be an appropriate treatment strategy in this young and otherwise healthy patient cohort. According to our analysis, EP is feasible and safe in centers with knowledge of specific anatomic characteristics of congenital heart disease and when the appropriate technical infrastructure is present. Access to ablation site was performed by remote magnetic navigation in the majority of procedures. The floppy catheter was navigated through the neo-aortic as well as through the aortic valve without observable peri- or postinterventional complications. Mapping with three-dimensional image integration facilitated EP and led to a relatively low radiation exposure with the known benefits for the patient as well as for the healthcare professionals involved in the procedure. Abstract Figure.

scholarly journals Arrhythmias in Patients with Congenital Heart Disease: a Modern View of the Problem

2019 ◽  
pp. 52-56
Author(s):  
O. S. Stychynskyi ◽  
P. O. Almiz ◽  
A. V. Topchii ◽  
M. M. Petkanych ◽  
V. V. Lazoryshynets
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Cardiac Death ◽  
Congenital Heart ◽  
Heart Defects ◽  
Heart Rhythm ◽  
Surgical Correction ◽  
Current Trends ◽  
Cardioverter Defibrillators

Thanks to the successes of modern cardiac surgery, more and more patients with congenital heart disease (CHD) reach adulthood, with approximately one in four having various heart rhythm disturbances. Their causes are both the CHD themselves and the consequences of surgical or interventional intervention. Arrhythmias in this category of patients worsen the quality of life, lead to serious complications, and can cause sudden cardiac death. The paper summarizes and analyzes current trends and recommendations of the world’s leading specialized communities for the management of patients with congenital heart disease with cardiac arrhythmias. The article reflects approaches to the management and monitoring of this category of patients, including asymptomatic ones. The necessity of early detection of arrhythmia and the involvement of a team of specialists in specialized centers for the development of tactics and treatment after surgical correction is justified. Also discussed are the issues of indications for electrophysiological research and its feasibility, the possibility and effectiveness of catheter destruction, the need for continuous drug therapy, indications for implantation of artificial pacemakers and cardioverter-defibrillators. The paper also reflects the question of various mechanisms of the development of arrhythmia in patients after surgical correction of congenital heart defects, as well as highlighted the possible ways of preventing arrhythmogenesis in patients after surgical correction.

scholarly journals Personalized Genetic Diagnosis of Congenital Heart Defects in Newborns

2021 ◽  
Vol 11 (6) ◽  
pp. 562
Author(s):  
Olga María Diz ◽  
Rocio Toro ◽  
Sergi Cesar ◽  
Olga Gomez ◽  
Georgia Sarquella-Brugada ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart Defects ◽  
Congenital Malformations ◽  
Congenital Heart ◽  
Heart Diseases ◽  
Heart Defects ◽  
Genetic Diagnosis ◽  
Single Nucleotide Variants ◽  
Personalized Approach

Congenital heart disease is a group of pathologies characterized by structural malformations of the heart or great vessels. These alterations occur during the embryonic period and are the most frequently observed severe congenital malformations, the main cause of neonatal mortality due to malformation, and the second most frequent congenital malformations overall after malformations of the central nervous system. The severity of different types of congenital heart disease varies depending on the combination of associated anatomical defects. The causes of these malformations are usually considered multifactorial, but genetic variants play a key role. Currently, use of high-throughput genetic technologies allows identification of pathogenic aneuploidies, deletions/duplications of large segments, as well as rare single nucleotide variants. The high incidence of congenital heart disease as well as the associated complications makes it necessary to establish a diagnosis as early as possible to adopt the most appropriate measures in a personalized approach. In this review, we provide an exhaustive update of the genetic bases of the most frequent congenital heart diseases as well as other syndromes associated with congenital heart defects, and how genetic data can be translated to clinical practice in a personalized approach.

Sign in / Sign up

Export Citation Format

Share Document