scholarly journals Acute Myocardial Infarction with Myocardial Perfusion Defect Detected by Contrast-Enhanced Computed Tomography

2009 ◽  
Vol 48 (14) ◽  
pp. 1235-1238 ◽  
Author(s):  
Tetsuo Ichinose ◽  
Miki Yamase ◽  
Yuki Yokomatsu ◽  
Yasunobu Kawano ◽  
Hakuoh Konishi ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Computed Tomography ◽  
Acute Myocardial Infarction ◽  
Myocardial Perfusion ◽  
Perfusion Defect ◽  
Myocardial Perfusion Defect ◽  
Contrast Enhanced ◽  
Enhanced Computed Tomography ◽  
Contrast Enhanced Computed Tomography

Abstract 4180: Assessment of Hibernating Myocardium by Contrast Enhanced Computed Tomography in a Porcine Model

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Gardar Sigurdsson ◽  
Edward O McFalls ◽  
Jesus A Cabrera ◽  
Melanie Crampton ◽  
Herbert B Ward ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Myocardial Perfusion ◽  
Coronary Stenosis ◽  
Porcine Model ◽  
Left Ventricular ◽  
Hibernating Myocardium ◽  
Signal Density ◽  
Contrast Enhanced ◽  
Enhanced Computed Tomography ◽  
Contrast Enhanced Computed Tomography

Contrast enhanced computed tomography (CT) is able to assess coronary stenosis and left ventricular function. Due to first pass effect it is able to assess surrogate markers of myocardial perfusion. We assessed the hypothesis that computed tomography can detect hibernating myocardium. Methods and results: A well-established porcine model of hibernating myocardium was used for this study. In this model of chronic coronary stenosis there is ~20% reduction in regional myocardial perfusion. Six pigs underwent instrumentation of the proximal left anterior descending (LAD) coronary artery with an external constrictor. Paired Student-T test was used to compare LAD territory and opposite myocardial segments. After 12 weeks echocardiographic studies detected regional left ventricular dysfunction by M-mode to the LAD territory (Table ). At that time EKG guided computed tomography showed severe stenosis to the LAD. Myocardial signal density (MSD) by CT was assessed in 24 opposing segments during diastole (Hounsfield Units). MSD within the territory of the LAD was significantly lower than MSD of opposing segments (Table ). Ratio of signal density (RSD) between myocardium and left ventricular cavity was significantly lower within the LAD territory in comparison to opposing segments (Table ). Conclusion: In a well-established porcine model of hibernating myocardium contrast enhanced computed tomography was able to detect areas of decreased attenuation suggesting that CT might be able to detect hibernating myocardium. Table

scholarly journals Porcine Ex Vivo Liver Phantom for Dynamic Contrast-Enhanced Computed Tomography

2011 ◽  
Vol 46 (9) ◽  
pp. 586-593 ◽  
Author(s):  
Scott M. Thompson ◽  
Juan C. Ramirez-Giraldo ◽  
Bruce Knudsen ◽  
Joseph P. Grande ◽  
Jodie A. Christner ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Ex Vivo ◽  
Dynamic Contrast Enhanced ◽  
Contrast Enhanced ◽  
Enhanced Computed Tomography ◽  
Liver Phantom ◽  
Contrast Enhanced Computed Tomography

scholarly journals Contrast enhanced computed tomography findings in 105 horse distal extremities.

2021 ◽  
pp. 103704
Author(s):  
Frederik Pauwels ◽  
Angela Hartmann ◽  
John Al-Alawneh ◽  
Paul Wightman ◽  
Jimmy Saunders
Keyword(s):  
Computed Tomography ◽  
Contrast Enhanced ◽  
Enhanced Computed Tomography ◽  
Contrast Enhanced Computed Tomography

scholarly journals Self-navigated 3D whole-heart MRA for non-enhanced surveillance of thoracic aortic dilation: a comparison to CTA

2021 ◽  
Vol 22 (Supplement_1) ◽  
Author(s):  
P Poskaite ◽  
M Pamminger ◽  
C Kranewitter ◽  
C Kremser ◽  
M Reindl ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Image Quality ◽  
Aortic Aneurysm ◽  
Thoracic Aortic Aneurysm ◽  
Aortic Dilation ◽  
Subjective Image Quality ◽  
Contrast Enhanced ◽  
Whole Heart ◽  
Enhanced Computed Tomography ◽  
Contrast Enhanced Computed Tomography

Abstract Funding Acknowledgements Type of funding sources: None. Background The natural history of thoracic aortic aneurysm (TAA) is one of progressive expansion. Asymptomatic patients who do not meet criteria for repair require conservative management including ongoing aneurysm surveillance, mostly carried out by contrast-enhanced computed tomography angiography (CTA). Purpose To prospectively compare image quality and reliability of a prototype non-contrast, self-navigated 3D whole-heart magnetic resonance angiography (MRA) with contrast-enhanced computed tomography angiography (CTA) for sizing of thoracic aortic aneurysm (TAA). Methods Self-navigated 3D whole-heart 1.5 T MRA was performed in 20 patients (aged 67 ± 8.6 years, 75% male) for sizing of TAA; a subgroup of 18 (90%) patients underwent additional contrast-enhanced CTA on the same day. Subjective image quality was scored according to a 4-point Likert scale and ratings between observers were compared by Cohen’s Kappa statistics. Continuous MRA and CTA measurements were analyzed with regression and Bland-Altman analysis. Results Overall subjective image quality as rated by two observers was 1 [interquartile range (IQR) 1-2] for self-navigated MRA and 1.5 [IQR 1-2] for CTA (p = 0.717). For MRA a perfect inter-observer agreement was found for presence of artefacts and subjective image sharpness (κ=1). Subjective signal inhomogeneity correlated highly with objectively quantified inhomogeneity of the blood pool signal (r = 0.78-0.824, all p <0.0001). Maximum diameters of TAA as measured by self-navigated MRA and CTA showed excellent correlation (r = 0.997, p < 0.0001) without significant inter-method bias (bias -0.0278, lower and upper limit of agreement -0.74 and 0.68, p = 0.749). Inter- and intraobserver correlation of aortic aneurysm as measured by MRA was excellent (r = 0.963 and 0.967, respectively) without significant bias (all p ≤ 0.05). Conclusion Self-navigated 3D whole-heart MRA enables reliable contrast- and radiation free aortic dilation surveillance without significant difference to standardized CTA while providing predictable acquisition time and by offering excellent image quality. Abstract Figure.

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