Mechanism of a Mutation in Non-Structural Protein 1 Inducing High Pathogenicity of Avian Influenza Virus H5N1

2016 ◽  
Vol 23 (4) ◽  
pp. 372-378 ◽  
Author(s):  
Yusuke S. Kato ◽  
Kiyoshi Fukui ◽  
Kazuo Suzuki
Keyword(s):  
Influenza Virus ◽  
Avian Influenza ◽  
Avian Influenza Virus ◽  
Structural Protein ◽  
Virus H5n1 ◽  
High Pathogenicity ◽  
Avian Influenza Virus H5n1

scholarly journals Source of High Pathogenicity of an Avian Influenza Virus H5N1: Why H5 Is Better Cleaved by Furin

2008 ◽  
Vol 95 (1) ◽  
pp. 128-134 ◽  
Author(s):  
Panita Decha ◽  
Thanyada Rungrotmongkol ◽  
Pathumwadee Intharathep ◽  
Maturos Malaisree ◽  
Ornjira Aruksakunwong ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Avian Influenza ◽  
Avian Influenza Virus ◽  
Virus H5n1 ◽  
High Pathogenicity ◽  
Avian Influenza Virus H5n1

scholarly journals Experimental Infection and Natural Contact Exposure of Dogs with Avian Influenza Virus (H5N1)

2008 ◽  
Vol 14 (2) ◽  
pp. 308-310 ◽  
Author(s):  
Matthias Giese ◽  
Timm C. Harder ◽  
Jens P. Teifke ◽  
Robert Klopfleisch ◽  
Angele Breithaupt ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Avian Influenza ◽  
Avian Influenza Virus ◽  
Experimental Infection ◽  
Virus H5n1 ◽  
Avian Influenza Virus H5n1 ◽  
Contact Exposure

scholarly journals Pathology of clade 2.3.2.1 avian influenza virus (H5N1) infection in quails and ducks in Bangladesh

2018 ◽  
Vol 48 (1) ◽  
pp. 73-79 ◽  
Author(s):  
Mohammed Nooruzzaman ◽  
Md. Enamul Haque ◽  
Emdadul Haque Chowdhury ◽  
Mohammad Rafiqul Islam
Keyword(s):  
Influenza Virus ◽  
Avian Influenza ◽  
Avian Influenza Virus ◽  
H5n1 Infection ◽  
Virus H5n1 ◽  
Avian Influenza Virus H5n1

scholarly journals Two-dimensional antigenic dendrogram and phylogenetic tree of avian influenza virus H5N1

2011 ◽  
Vol 64 (2) ◽  
pp. 205-211 ◽  
Author(s):  
Alexander C.K. Lai ◽  
Wai-lan Wu ◽  
Siu-ying Lau ◽  
Yi Guan ◽  
Honglin Chen
Keyword(s):  
Influenza Virus ◽  
Avian Influenza ◽  
Phylogenetic Tree ◽  
Avian Influenza Virus ◽  
Two Dimensional ◽  
Virus H5n1 ◽  
Avian Influenza Virus H5n1

scholarly journals Chronic Heat Stress Weakened the Innate Immunity and Increased the Virulence of Highly Pathogenic Avian Influenza Virus H5N1 in Mice

2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Yi Jin ◽  
Yanxin Hu ◽  
Deping Han ◽  
Ming Wang
Keyword(s):  
Innate Immunity ◽  
Influenza Virus ◽  
Heat Stress ◽  
Avian Influenza ◽  
Respiratory Tract ◽  
Avian Influenza Virus ◽  
Mrna Levels ◽  
Local Immunity ◽  
Virus H5n1 ◽  
Avian Influenza Virus H5n1

Chronic heat stress (CHS) can negatively affect immune response in animals. In this study we assessed the effects of CHS on host innate immunity and avian influenza virus H5N1 infection in mice. Mice were divided into two groups: CHS and thermally neutral (TN). The CHS treatment group exhibited reduced local immunity in the respiratory tract, including the number of pulmonary alveolar macrophages and lesions in the nasal mucosa, trachea, and lungs. Meanwhile, CHS retarded dendritic cells (DCs) maturation and reduced the mRNA levels of IL-6 and IFN-βsignificantly (P<.05). After the CHS treatment, mice were infected with H5N1 virus. The mortality rate and viral load in the lungs of CHS group were higher than those of TN group. The results suggest that the CHS treatment could suppress local immunity in the respiratory tract and innate host immunity in mice significantly and moderately increased the virulence in H5N1-infected mice.

scholarly journals Specific antibody response of mice after immunization with COS-7 cell derived avian influenza virus (H5N1) recombinant proteins

2007 ◽  
Vol 5 (1) ◽  
pp. 10 ◽  
Author(s):  
Navin Horthongkham ◽  
Tananun Srihtrakul ◽  
Niracha Athipanyasilp ◽  
Sontana Siritantikorn ◽  
Wannee Kantakamalakul ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Avian Influenza ◽  
Antibody Response ◽  
Avian Influenza Virus ◽  
Recombinant Proteins ◽  
Specific Antibody ◽  
Specific Antibody Response ◽  
Virus H5n1 ◽  
Avian Influenza Virus H5n1
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