Solid Lipid Nanoparticles as a Delivery System for Zataria multiflora Essential Oil: Formulation and Characterization

2013 ◽  
Vol 10 (2) ◽  
pp. 151-157 ◽  
Author(s):  
Eskandar Moghimipour ◽  
Zahra Ramezani ◽  
Somayeh Handali
Keyword(s):  
Essential Oil ◽  
Delivery System ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Zataria Multiflora ◽  
Solid Lipid ◽  
Oil Formulation

scholarly journals High anticancer efficacy of solid lipid nanoparticles containing Zataria multiflora essential oil against breast cancer and melanoma cell lines

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Alireza Valizadeh ◽  
Ali Asghar Khaleghi ◽  
Ghazaal Roozitalab ◽  
Mahmoud Osanloo
Keyword(s):  
Breast Cancer ◽  
Essential Oil ◽  
Solid Lipid Nanoparticles ◽  
Entrapment Efficiency ◽  
Lipid Nanoparticles ◽  
In Vivo Studies ◽  
Zataria Multiflora ◽  
Anticancer Efficacy ◽  
Solid Lipid

Abstract Background The cancer burden is rising rapidly worldwide, and it annually causes about 8.8 million deaths worldwide. Due to chemical drugs’ side effects and the emergence of resistance, the development of new green drugs has received much attention. We aimed to investigate whether solid-lipid nanoparticles containing essential oil of Zataria multiflora (ZMSLN) enhanced the anticancer efficacy of the essential oil against breast cancer (MDA-MB-468) and melanoma (A-375) cells. Results ZMSLN was prepared by the high-pressure homogenizer method; particle size 176 ± 8 nm, polydispersity index 0.22 ± 0.1, entrapment efficiency 67 ± 5%. The essential oil showed a dose-dependent antiproliferative effect on MDA-MB-468 and A-375 cells at all examined concentrations (75, 150, 300, 600, and 1200 μg/mL). Interestingly, after treating both cells with 75 μg/mL of ZMSLN, their viabilities were reduced to under 13%. Conclusion The finding showed that ZMSLN had a distinct antiproliferative efficacy; it could thus be considered a green anticancer candidate for further in vivo and in vivo studies.

scholarly journals Solid-lipid nanoparticles (SLN)s containing Zataria multiflora essential oil with no-cytotoxicity and potent repellent activity against Anopheles stephensi

2020 ◽  
Author(s):  
Hamid Reza Kelidari ◽  
Mohammad Djaefar Moemenbellah-Fard ◽  
Katayon Morteza-Semnani ◽  
Fatemeh Amoozegar ◽  
Marziae Shahriari-Namadi ◽  
...  
Keyword(s):  
Essential Oil ◽  
Solid Lipid Nanoparticles ◽  
Anopheles Stephensi ◽  
Lipid Nanoparticles ◽  
Repellent Activity ◽  
Zataria Multiflora ◽  
Solid Lipid

scholarly journals Positive-charged solid lipid nanoparticles as paclitaxel drug delivery system in glioblastoma treatment

2014 ◽  
Vol 88 (3) ◽  
pp. 746-758 ◽  
Author(s):  
Daniela Chirio ◽  
Marina Gallarate ◽  
Elena Peira ◽  
Luigi Battaglia ◽  
Elisabetta Muntoni ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Solid Lipid

scholarly journals Application of normal essential oil and loaded-solid lipid nanoparticles as antioxidant

2019 ◽  
Vol 44 (2) ◽  
pp. 180-186
Author(s):  
M. Taha ◽  
M. EL-Dannasoury ◽  
S. Mahmoud ◽  
M. Moghazy
Keyword(s):  
Essential Oil ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Solid Lipid

Solid lipid nanoparticles incorporated in dextran hydrogels: A new drug delivery system for oral formulations

2006 ◽  
Vol 325 (1-2) ◽  
pp. 140-146 ◽  
Author(s):  
Maria Antonietta Casadei ◽  
Felice Cerreto ◽  
Stefania Cesa ◽  
Maria Giannuzzo ◽  
Michelle Feeney ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Solid Lipid ◽  
New Drug ◽  
Oral Formulations
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