Despite an Extensive Sequence Analysis Identification of Functional Candidates Amongst Hypothetical Proteins of Neisseria gonorrhoeae

2016 ◽  
Vol 13 (5) ◽  
pp. 451-464 ◽  
Author(s):  
Kundan Kumar ◽  
Amresh Prakash ◽  
Asimul Islam ◽  
Faizan Ahmad ◽  
Md. Imtaiyaz Hassan
Keyword(s):  
Sequence Analysis ◽  
Neisseria Gonorrhoeae ◽  
Hypothetical Proteins ◽  
Extensive Sequence

scholarly journals Localization of Antibody-Binding Sites by Sequence Analysis of Cloned Pilin Genes from Neisseria Gonorrhoeae

Microbiology ◽  
1987 ◽  
Vol 133 (4) ◽  
pp. 825-833 ◽  
Author(s):  
I. J. Nicolson ◽  
A. C. F. Perry ◽  
M. Virji ◽  
J. E. Heckels ◽  
J. R. Saunders
Keyword(s):  
Sequence Analysis ◽  
Neisseria Gonorrhoeae ◽  
Binding Sites ◽  
Antibody Binding

scholarly journals Variation of gonococcal lipooligosaccharide structure is due to alterations in poly-G tracts in lgt genes encoding glycosyl transferases.

1996 ◽  
Vol 183 (1) ◽  
pp. 323-327 ◽  
Author(s):  
Q L Yang ◽  
E C Gotschlich
Keyword(s):  
Sequence Analysis ◽  
Neisseria Gonorrhoeae ◽  
Experimental Evidence ◽  
High Frequency ◽  
Genetic Mechanism ◽  
Frequency Variation ◽  
Alpha Chain ◽  
Glycosyl Transferases ◽  
Genes Encoding

The lipooligosaccharide (LOS) expressed by gonococci spontaneously varies its structure at high frequency, but the underlying genetic mechanism has not been described. We have previously reported that the genes encoding the glycosyl transferases responsible for the biosynthesis of the variable alpha chain of the LOS of Neisseria gonorrhoeae are located in a locus containing five genes, lgtA, lgtB, lgtC, lgtD, and lgtE. Sequence analysis showed that lgtA, lgtC, and lgtD contained poly-G tracts within the coding frames, leading to the hypothesis that shifts in the number of guanosine residues in the poly-G tracts might be responsible for the high frequency variation in structure of gonococcal LOS. We now provide experimental evidence confirming this hypothesis.

Extensive sequence analysis ofCFTR,SCNN1A,SCNN1B,SCNN1GandSERPINA1suggests an oligogenic basis for cystic fibrosis-like phenotypes

2013 ◽  
Vol 86 (1) ◽  
pp. 91-95 ◽  
Author(s):  
M.D. Ramos ◽  
D. Trujillano ◽  
R. Olivar ◽  
F. Sotillo ◽  
S. Ossowski ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Sequence Analysis ◽  
Extensive Sequence

Sequence Analysis of the Family of Penicillinase-Producing Plasmids of Neisseria gonorrhoeae

Plasmid ◽  
2000 ◽  
Vol 43 (1) ◽  
pp. 24-34 ◽  
Author(s):  
Franco Pagotto ◽  
Abu-Tholib Aman ◽  
Lai-King Ng ◽  
Kwok-Him Yeung ◽  
Maggie Brett ◽  
...  
Keyword(s):  
Sequence Analysis ◽  
Neisseria Gonorrhoeae ◽  
The Family

scholarly journals Identification of TEM-135 β-Lactamase in Penicillinase-Producing Neisseria gonorrhoeae Strains in Japan

2010 ◽  
Vol 54 (7) ◽  
pp. 3021-3023 ◽  
Author(s):  
Makoto Ohnishi ◽  
Emi Ono ◽  
Ken Shimuta ◽  
Haruo Watanabe ◽  
Noboru Okamura
Keyword(s):  
Sequence Analysis ◽  
Neisseria Gonorrhoeae ◽  
Multilocus Sequence Typing ◽  
Lactamase Gene

ABSTRACT Ten penicillinase-producing Neisseria gonorrhoeae (PPNG) strains isolated from 2000 to 2008 were characterized by multilocus sequence typing, multiantigen sequence typing, and plasmid typing. Sequence analysis showed that 8 strains contained a TEM-1 β-lactamase gene. However, two other genetically distinct PPNG strains, isolated in 2004 and 2008, each contained a TEM-135 β-lactamase on different plasmids, a Toronto/Rio type R plasmid and an Asia type R plasmid, suggesting independent origins of these PPNG strains.

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