State of the Art of Biochemical Markers in Metastatic Bone Disease and the Role of Bisphosphonates as Therapeutic Agents

2005 ◽  
Vol 1 (3) ◽  
pp. 225-241 ◽  
Author(s):  
Ioannis Kanakis ◽  
Achilleas Theocharis ◽  
Argiris Noulas ◽  
Nikos Karamanos
2018 ◽  
Vol 9 (4) ◽  
Author(s):  
Andrew R. Summers ◽  
Travis Philipp ◽  
Jacob D. Mikula ◽  
Kenneth R. Gundle

Metastatic bone disease affects approximately 300,000 people in the United States, and the burden is rising. These patients experience significant morbidity and decreased survival. The management of these patients requires coordinated care among a multidisciplinary team of physicians, including orthopaedic surgeons. This article reviews the role of radiation therapy after orthopaedic stabilization of impending or realized pathologic extremity fractures. Orthopaedic surgeons have an opportunity to benefit patients with metastatic bone disease by referring them for consideration of post-operative radiation therapy. Further research into rates of referral and the effect on clinical outcomes in this population is needed.


2015 ◽  
Vol 4 (3) ◽  
pp. 92-97 ◽  
Author(s):  
Mine Araz ◽  
Gülseren Aras ◽  
Özlem N. Küçük

Pain ◽  
1998 ◽  
Vol 78 (3) ◽  
pp. 157-169 ◽  
Author(s):  
F Fulfaro ◽  
A Casuccio ◽  
C Ticozzi ◽  
C Ripamonti

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