Editorial: [Hot Topic: The Role of Nuclear Medicine in the Management of Patients with Glioblastoma Multiforme]

2012 ◽  
Vol 5 (4) ◽  
pp. 289-291
Author(s):  
Ioannis N. Mavridis
Keyword(s):  
Nuclear Medicine ◽  
Glioblastoma Multiforme

Glioblastoma Multiforme Imaging: The Role of Nuclear Medicine

2012 ◽  
Vol 5 (4) ◽  
pp. 308-313 ◽  
Author(s):  
George A. Alexiou ◽  
Spyridon Tsiouris ◽  
Spyridon Voulgaris ◽  
Athanasios P. Kyritsis ◽  
Andreas D. Fotopoulos
Keyword(s):  
Nuclear Medicine ◽  
Glioblastoma Multiforme

The role of nuclear medicine in orthopaedics

1994 ◽  
Vol 15 (5) ◽  
pp. 341-360???360 ◽  
Author(s):  
P. J. RYAN ◽  
I. FOGELMAN
Keyword(s):  
Nuclear Medicine

Deciphering the signaling pathways of cancer stem cells of glioblastoma multiforme: Role of Akt/mTOR and MAPK pathways

2011 ◽  
Vol 51 (1) ◽  
pp. 164-170 ◽  
Author(s):  
Meena Jhanwar-Uniyal ◽  
Ladislau Albert ◽  
Elise McKenna ◽  
Michael Karsy ◽  
Priya Rajdev ◽  
...  
Keyword(s):  
Stem Cells ◽  
Glioblastoma Multiforme ◽  
Cancer Stem Cells ◽  
Signaling Pathways ◽  
Mapk Pathways

scholarly journals Combining experiments and in silico modeling to infer the role of adhesion and proliferation on the collective dynamics of cells

2021 ◽  
Author(s):  
Hygor P. M. Melo ◽  
F. Raquel Maia ◽  
André S. Nunes ◽  
Rui L. Reis ◽  
Joaquim M. Oliveira ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cell Adhesion ◽  
Glioblastoma Multiforme ◽  
In Silico ◽  
Relative Importance ◽  
Collective Dynamics ◽  
Surfaces And Interfaces ◽  
In Silico Modeling ◽  
Cell Cell

ABSTRACTThe collective dynamics of cells on surfaces and interfaces poses technological and theoretical challenges in the study of morphogenesis, tissue engineering, and cancer. Different mechanisms are at play, including, cell-cell adhesion, cell motility, and proliferation. However, the relative importance of each one is elusive. Here, experiments with a culture of glioblastoma multiforme cells on a substrate are combined with in silico modeling to infer the rate of each mechanism. By parametrizing these rates, the time-dependence of the spatial correlation observed experimentally is reproduced. The obtained results suggest a reduction in cell-cell adhesion with the density of cells. The reason for such reduction and possible implications for the collective dynamics of cancer cells are discussed.

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