scholarly journals Therapeutic Mild Hypothermia and the Pharmacokinetics of Drugs in Trauma Brain Injury (TBI) Patients with a Focus on Sedation, Anticonvulsant and Antibiotic Therapy

2013 ◽  
Vol 6 (1) ◽  
pp. 31-38 ◽  
Author(s):  
F. Carlotta Bagna
Keyword(s):  
Brain Injury ◽  
Antibiotic Therapy ◽  
Mild Hypothermia ◽  
Trauma Brain Injury ◽  
Therapeutic Mild Hypothermia

Effects of therapeutic mild hypothermia on patients with severe traumatic brain injury after craniotomy

2007 ◽  
Vol 22 (3) ◽  
pp. 229-235 ◽  
Author(s):  
Wusi Qiu ◽  
Ying Zhang ◽  
Hong Sheng ◽  
Jianmin Zhang ◽  
Weiming Wang ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Severe Traumatic Brain Injury ◽  
Mild Hypothermia ◽  
Therapeutic Mild Hypothermia

Effect of Therapeutic Mild Hypothermia on the Genomics of the Hippocampus After Moderate Traumatic Brain Injury in Rats

Neurosurgery ◽  
2010 ◽  
Vol 67 (3) ◽  
pp. 730-742 ◽  
Author(s):  
Jun-feng Feng ◽  
Kui-ming Zhang ◽  
Ji-yao Jiang ◽  
Guo-yi Gao ◽  
Xi'an Fu ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Hypothermia ◽  
Moderate Traumatic Brain Injury ◽  
Therapeutic Mild Hypothermia

scholarly journals Intraoperative hypothermia during vascular neurosurgical procedures

2009 ◽  
Vol 26 (5) ◽  
pp. E24 ◽  
Author(s):  
Raymond Choi ◽  
Robert H. Andres ◽  
Gary K. Steinberg ◽  
Raphael Guzman
Keyword(s):  
Traumatic Brain Injury ◽  
Clinical Trials ◽  
Brain Injury ◽  
Animal Models ◽  
Mild Hypothermia ◽  
Scientific Evidence ◽  
Neurosurgical Procedures ◽  
Ischemic Damage ◽  
Intraoperative Hypothermia ◽  
Improved Outcomes

Increasing evidence in animal models and clinical trials for stroke, hypoxic encephalopathy for children, and traumatic brain injury have shown that mild hypothermia may attenuate ischemic damage and improve neurological outcome. However, it is less clear if mild intraoperative hypothermia during vascular neurosurgical procedures results in improved outcomes for patients. This review examines the scientific evidence behind hypothermia as a treatment and discusses factors that may be important for the use of this adjuvant technique, including cooling temperature, duration of hypothermia, and rate of rewarming.

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