Malignant Priapism

Malignant priapism secondary to penile metastases is a rare condition. This term was originally used by Peacock in 1938 to describe a condition of painful induration and erection of the penis due to metastatic infiltration by a neoplasm. In the current literature there are 512 case reports. The primary tumor sites are bladder, prostate and rectum. The treatment has only palliative intent and consists of local tumor excision, penectomy, radiotherapy and chemotherapy. We present one case of malignant priapism originated from prostate cancer, and two from urothelial carcinoma of the bladder. Different approaches in diagnosis and therapy were performed. The entire three patient reported a relief of the pain following the treatment, with an improvement of their quality of life, even though it was only temporary as a palliative. Malignant priapism is a rare medical emergency. Penile/pelvis magnetic resonance imaging (MRI) scan and corporal biopsies are considered an effective method of diagnosis of the primary organ site.

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Malignant Priapism: Report of Primary Carcinoma of the Urethra with Priapism

The Journal of Urology ◽

10.1016/s0022-5347(17)70608-8 ◽

1943 ◽

Vol 49 (5) ◽

pp. 732-744 ◽

Cited By ~ 15

Author(s):

Kano Ikeda ◽

Frederic E.B. Foley ◽

John Rosenow

Keyword(s):

Primary Carcinoma ◽

Malignant Priapism

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European Urology ◽

10.1159/000472557 ◽

1985 ◽

Vol 11 (6) ◽

pp. 431-432 ◽

Cited By ~ 8

Author(s):

S. Witters ◽

M. Cornelissen ◽

R.L. Vereecken

Keyword(s):

Malignant Priapism

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Metastatic plasmacytoid bladder cancer causing malignant priapism

BMJ Case Reports ◽

10.1136/bcr-2018-228088 ◽

2019 ◽

Vol 12 (7) ◽

pp. e228088

Author(s):

Ryan Pereira ◽

Marlon Perera ◽

Handoo Rhee

Keyword(s):

Bladder Cancer ◽

Anterior Abdominal Wall ◽

Subcutaneous Tissue ◽

Bladder Wall ◽

Transitional Cell ◽

Penile Shaft ◽

Iliac Region ◽

Left Flank ◽

Bladder Disease ◽

Malignant Priapism

An 81-year-old man presented to medical services with pelvic pain and evolving urinary retention over 3 months. The patient was found to have a tense glans and penile shaft with surrounding induration consistent with malignant priapism. The extent of the induration included the suprapubic region, scrotum, left iliac region and left flank. A CT scan demonstrated an enhancing, pedunculated lesion arising from the anterior bladder wall measuring 30×31×20 mm. There were multiple enlarged left inguinal lymph nodes. Core biopsies of the subcutaneous tissue on the anterior abdominal wall demonstrated plasmacytoid urothelial carcinoma. The majority of patients with plasmacytoid variant of transitional cell carcinoma will present with >stage 3 bladder disease

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