scholarly journals Information technologies’ role in optimizing the application of drugs in clinical practice: a view of a clinical pharmacologist

2021 ◽  
Vol 2 (4) ◽  
pp. 30-32
Author(s):  
D. A. Sychev
Keyword(s):  
Clinical Practice ◽  
Drug Therapy ◽  
Information Technologies ◽  
Medical Information ◽  
Medical Decision ◽  
Efficacy And Safety ◽  
Clinical Pharmacologist ◽  
Medical Information Systems ◽  
Medical Decision Support ◽  
Medical Decision Support Systems

Currently, the development and implementation of computerized medical decision support systems (CMDSS) is an effective tool aimed at optimizing drug therapy in clinical practice. It has been proven in clinical studies their use can increase the efficacy and safety of pharmacotherapy for a number of socially significant diseases. An active integration of CMDSS into medical information systems of medical organizations is required.

The Good, the Bad and the Ugly in App Diagnosis: Outcomes and Implications by Example

2021 ◽  
Vol 66 (Special Issue) ◽  
pp. 38-38
Author(s):  
Sorana D. Bolboacă ◽  
◽  
Adriana Elena Bulboacă ◽  
◽  
◽  
...  
Keyword(s):  
Decision Support ◽  
Clinical Decision ◽  
Medical Decision ◽  
Normal Body Mass Index ◽  
Disk Herniation ◽  
Scientific Evaluation ◽  
Medical Decision Support ◽  
Lower Back ◽  
Clinical Scenarios ◽  
Medical Decision Support Systems

"The Clinical Decision Support (CDS), a form of artificial intelligence (AI), consider physician expertise and cognitive function along with patient’s data as the input and case-specific medical decision as an output. The improvements in physician’s performances when using a CDS ranges from 13% to 68%. The AI applications are of large interest nowadays, and a lot of effort is also put in the development of IT applications in healthcare. Medical decision support systems for non-medical staff users (MDSS-NMSF) as phone applications are nowadays available on the market. A MDSS-NMSF app is generally not accompanied by a scientific evaluation of the performances, even if they are freely available or not. Two clinical scenarios were created, and Doctor31 retrieved the diagnosis decisions. First scenario: man, 29 years old, and three symptoms: dysphagia, weight loss (normal body mass index), and tiredness. Second scenario: women, 47 years old with L5-S1 disk herniation, abnormal anti-TPO antibodies, lower back pain (burning sensations), constipation, and tiredness. The outcome possible effects and implications, as well as vulnerabilities induced on the used, are highlighted and discussed. "

scholarly journals KID Project: an internet-based digital video atlas of capsule endoscopy for research purposes

2017 ◽  
Vol 05 (06) ◽  
pp. E477-E483 ◽  
Author(s):  
Anastasios Koulaouzidis ◽  
Dimitris Iakovidis ◽  
Diana Yung ◽  
Emanuele Rondonotti ◽  
Uri Kopylov ◽  
...  
Keyword(s):  
Open Source ◽  
Open Source Software ◽  
Capsule Endoscopy ◽  
Diagnostic Yield ◽  
Jaccard Index ◽  
Machine Learning Algorithms ◽  
Medical Decision ◽  
Annotation Tool ◽  
Medical Decision Support ◽  
Medical Decision Support Systems

Abstract Background and aims Capsule endoscopy (CE) has revolutionized small-bowel (SB) investigation. Computational methods can enhance diagnostic yield (DY); however, incorporating machine learning algorithms (MLAs) into CE reading is difficult as large amounts of image annotations are required for training. Current databases lack graphic annotations of pathologies and cannot be used. A novel database, KID, aims to provide a reference for research and development of medical decision support systems (MDSS) for CE. Methods Open-source software was used for the KID database. Clinicians contribute anonymized, annotated CE images and videos. Graphic annotations are supported by an open-access annotation tool (Ratsnake). We detail an experiment based on the KID database, examining differences in SB lesion measurement between human readers and a MLA. The Jaccard Index (JI) was used to evaluate similarity between annotations by the MLA and human readers. Results The MLA performed best in measuring lymphangiectasias with a JI of 81 ± 6 %. The other lesion types were: angioectasias (JI 64 ± 11 %), aphthae (JI 64 ± 8 %), chylous cysts (JI 70 ± 14 %), polypoid lesions (JI 75 ± 21 %), and ulcers (JI 56 ± 9 %). Conclusion MLA can perform as well as human readers in the measurement of SB angioectasias in white light (WL). Automated lesion measurement is therefore feasible. KID is currently the only open-source CE database developed specifically to aid development of MDSS. Our experiment demonstrates this potential.

Medical Outcome Prediction for Intensive Care Unit Patients

2012 ◽  
pp. 251-262
Author(s):  
Simone A. Ludwig ◽  
Stefanie Roos ◽  
Monique Frize ◽  
Nicole Yu
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Decision Support ◽  
Decision Support Systems ◽  
Support Systems ◽  
Medical Decision ◽  
Adult Intensive Care Unit ◽  
Medical Decision Support ◽  
Elimination Algorithm ◽  
Medical Decision Support Systems

The rate of people dying from medical errors in hospitals each year is very high. Errors that frequently occur during the course of providing health care are adverse drug events and improper transfusions, surgical injuries and wrong-site surgery, suicides, restraint-related injuries or death, falls, burns, pressure ulcers, and mistaken patient identities. Medical decision support systems play an increasingly important role in medical practice. By assisting physicians in making clinical decisions, medical decision support systems improve the quality of medical care. Two approaches have been investigated for the prediction of medical outcomes: “hours of ventilation” and the “mortality rate” in the adult intensive care unit. The first approach is based on neural networks with the weight-elimination algorithm, and the second is based on genetic programming. Both approaches are compared to commonly used machine learning algorithms. Results show that both algorithms developed score well for the outcomes selected.

Medical Outcome Prediction for Intensive Care Unit Patients

2012 ◽  
pp. 1068-1079
Author(s):  
Simone A. Ludwig ◽  
Stefanie Roos ◽  
Monique Frize ◽  
Nicole Yu
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Decision Support ◽  
Decision Support Systems ◽  
Support Systems ◽  
Medical Decision ◽  
Adult Intensive Care Unit ◽  
Medical Decision Support ◽  
Elimination Algorithm ◽  
Medical Decision Support Systems

The rate of people dying from medical errors in hospitals each year is very high. Errors that frequently occur during the course of providing health care are adverse drug events and improper transfusions, surgical injuries and wrong-site surgery, suicides, restraint-related injuries or death, falls, burns, pressure ulcers, and mistaken patient identities. Medical decision support systems play an increasingly important role in medical practice. By assisting physicians in making clinical decisions, medical decision support systems improve the quality of medical care. Two approaches have been investigated for the prediction of medical outcomes: “hours of ventilation” and the “mortality rate” in the adult intensive care unit. The first approach is based on neural networks with the weight-elimination algorithm, and the second is based on genetic programming. Both approaches are compared to commonly used machine learning algorithms. Results show that both algorithms developed score well for the outcomes selected.

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