scholarly journals The influence of baseline A1c on digital health coaching outcomes for adults with type 2 diabetes: A real-world retrospective cohort study (Preprint)

JMIR Diabetes ◽  
10.2196/24981 ◽  
2020 ◽  
Author(s):  
Martin Martin ◽  
Jonathan Patterson ◽  
Matt Allison ◽  
Blakely B O’Connor ◽  
Dhiren Patel
Keyword(s):  
Type 2 Diabetes ◽  
Cohort Study ◽  
Real World ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Digital Health ◽  
Health Coaching ◽  
Coaching Outcomes

scholarly journals Improved Glycemic Control Achieved by Switching to Insulin Degludec in Insulin-Treated Patients with Type 2 Diabetes in a Real-World Setting: a Non-interventional, Retrospective Cohort Study

2017 ◽  
Vol 8 (5) ◽  
pp. 1047-1055 ◽  
Author(s):  
Cheli Melzer Cohen ◽  
Brian Larsen Thorsted ◽  
Michael Lyng Wolden ◽  
Gabriel Chodick ◽  
Avraham Karasik
Keyword(s):  
Type 2 Diabetes ◽  
Cohort Study ◽  
Glycemic Control ◽  
Real World ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Insulin Degludec ◽  
Real World Setting

Real‐World Treatment Escalation from Metformin Monotherapy in Youth‐Onset Type 2 Diabetes Mellitus: A Retrospective Cohort Study

2021 ◽  
Author(s):  
Mary Ellen Vajravelu ◽  
Talia A. Hitt ◽  
Sandra Amaral ◽  
Lorraine E. Levitt Katz ◽  
Joyce M. Lee ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cohort Study ◽  
Real World ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Metformin Monotherapy ◽  
Treatment Escalation

21-OR: Real-World Treatment Escalation from Metformin Monotherapy in Youth-Onset Type 2 Diabetes Mellitus: A Retrospective Cohort Study

Diabetes ◽  
2021 ◽  
Vol 70 (Supplement 1) ◽  
pp. 21-OR
Author(s):  
MARY ELLEN VAJRAVELU ◽  
TALIA A. HITT ◽  
SANDRA AMARAL ◽  
LORRAINE E. KATZ ◽  
JOYCE M. LEE ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cohort Study ◽  
Real World ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Metformin Monotherapy ◽  
Treatment Escalation

scholarly journals Risk factors for diabetic foot complications among patients with type 2 diabetes in Austria–A registry‐based retrospective cohort study

2021 ◽  
Author(s):  
Sophia Rossboth ◽  
Benedikt Rossboth ◽  
Hans Schoenherr ◽  
Monika Lechleitner ◽  
Willi Oberaigner
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Diabetic Foot ◽  
Retrospective Cohort ◽  
Foot Complications

scholarly journals Is therapeutic inertia present in hyperglycaemia, hypertension and hypercholesterolaemia management among adults with type 2 diabetes in three health clinics in Malaysia? a retrospective cohort study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Boon-How Chew ◽  
Husni Hussain ◽  
Ziti Akthar Supian
Keyword(s):  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Ldl Cholesterol ◽  
Therapeutic Inertia ◽  
Treatment Targets ◽  
Health Clinics

Abstract Background Good-quality evidence has shown that early glycaemic, blood pressure and LDL-cholesterol control in people with type 2 diabetes (T2D) leads to better outcomes. In spite of that, diseases control have been inadequate globally, and therapeutic inertia could be one of the main cause. Evidence on therapeutic inertia has been lacking at primary care setting. This retrospective cohort study aimed to determine the proportions of therapeutic inertia when treatment targets of HbA1c, blood pressure and LDL-cholesterol were not achieved in adults with T2D at three public health clinics in Malaysia. Methods The index prescriptions were those that when the annual blood tests were reviewed. Prescriptions of medication were verified, compared to the preceding prescriptions and classified as 1) no change, 2) stepping up and 3) stepping down. The treatment targets were HbA1c < 7.0% (53 mmol/mol), blood pressure (BP) < 140/90 mmHg and LDL-cholesterol < 2.6 mmol/L. Therapeutic inertia was defined as no change in the medication use in the present of not reaching the treatment targets. Descriptive, univariable, multivariable logistic regression and sensitive analyses were conducted. Results A total of 552 cohorts were available for the assessment of therapeutic inertia (78.9% completion rate). The mean (SD) age and diabetes duration were 60.0 (9.9) years and 5.0 (6.0) years, respectively. High therapeutic inertia were observed in oral anti-diabetic (61–72%), anti-hypertensive (34–65%) and lipid-lowering therapies (56–77%), and lesser in insulin (34–52%). Insulin therapeutic inertia was more likely among those with shorter diabetes duration (adjusted OR 0.9, 95% CI 0.87, 0.98). Those who did not achieve treatment targets were less likely to experience therapeutic inertia: HbA1c ≥ 7.0%: adjusted OR 0.10 (0.04, 0.24); BP ≥ 140/90 mmHg: 0.28 (0.16, 0.50); LDL-cholesterol ≥ 2.6 mmol/L: 0.37 (0.22, 0.64). Conclusions Although therapeutic intensifications were more likely in the presence of non-achieved treatment targets but the proportions of therapeutic inertia were high. Possible causes of therapeutic inertia were less of the physician behaviours but might be more of patient-related non-adherence or non-availability of the oral medications. These observations require urgent identification and rectification to improve disease control, avoiding detrimental health implications and costly consequences. Trial registration Number NCT02730754, April 6, 2016.

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