Renal Mass Core Biopsy: Accuracy and Impact on Clinical Management

2007 ◽  
Vol 188 (2) ◽  
pp. 563-570 ◽  
Author(s):  
Katherine E. Maturen ◽  
Hanh V. Nghiem ◽  
Elaine M. Caoili ◽  
Ellen G. Higgins ◽  
J. Stuart Wolf ◽  
...  
Keyword(s):  
Clinical Management ◽  
Core Biopsy ◽  
Renal Mass

Implications on clinical management of the small renal mass in patients 80 years of age and older based on a retrospective review of the SEER database

2015 ◽  
Vol 47 (9) ◽  
pp. 1503-1508 ◽  
Author(s):  
Douglas H. Russell ◽  
Mitchell S. Wachtel ◽  
Heiko W. de Riese ◽  
Allan L. Haynes ◽  
Werner T. W. de Riese
Keyword(s):  
Retrospective Review ◽  
Clinical Management ◽  
Renal Mass ◽  
Seer Database ◽  
Small Renal Mass

The Diagnostic Accuracy of Percutaneous Renal Needle Core Biopsy and Its Potential Impact on the Clinical Management of Renal Cortical Neoplasms

2014 ◽  
Vol 138 (12) ◽  
pp. 1673-1679 ◽  
Author(s):  
Lan L. Gellert ◽  
Rohit Mehra ◽  
Ying-Bei Chen ◽  
Anuradha Gopalan ◽  
Samson W. Fine ◽  
...  
Keyword(s):  
Clinical Management ◽  
Renal Cell ◽  
Core Biopsy ◽  
Clear Cell ◽  
Renal Tumors ◽  
Low Grade ◽  
Renal Cell Carcinomas ◽  
Biopsy Diagnosis ◽  
Potential Impact ◽  
Renal Cortical Neoplasms

Context While biopsies are now increasingly being performed for the diagnosis of renal cortical neoplasms, the influence of the rendered pathological diagnoses on the clinical management is only rarely documented. Objectives To report our experience with consecutively performed renal biopsies and the potential impact of the diagnosis on subsequent clinical management. Design Material from needle biopsies performed consecutively at our institution between 2006 and 2011 was reviewed. The influence of the reported pathology results on the clinical management was determined from patient follow-up medical record review. Results In total, 218 percutaneous biopsies for renal masses were performed during this period. Among them, 181 (83%) yielded neoplastic tissue, including 81 clear cell renal cell carcinomas, 29 low-grade oncocytic neoplasms, 7 papillary renal cell carcinomas, 5 clear cell papillary renal cell carcinomas, 5 angiomyolipomas, and 14 urothelial carcinomas. Fourteen additional cases (6%) contained lesional material from clinically known nonneoplastic processes, for a total diagnostic yield of 89%. Twenty-three (11%) were nonrepresentative of lesional tissue. In 10 of these, repeat biopsies or resections established the diagnosis of renal tumors. Biopsy diagnosis was confirmed in 29 of 30 cases (97%) on subsequent nephrectomy. Following the biopsy diagnosis, there were significant differences in the clinical management; overall, 79% of clear cell renal cell carcinomas received therapeutic interventions, and 17% were put on active surveillance. In contrast, 77% of the benign or low-grade lesions were put on active surveillance. Conclusions Accurate and specific diagnosis can be rendered on renal core biopsy in most renal tumors, and the biopsy diagnosis can have a definitive role in their clinical management.

Clinical Management of Mucocele-Like Lesions of the Breast with Limited or no Epithelial Atypia on Core Biopsy: Experience from Two Institutions

2019 ◽  
Vol 26 (11) ◽  
pp. 3478-3488 ◽  
Author(s):  
Tanya W. Moseley ◽  
Sejal S. Shah ◽  
Christopher V. Nguyen ◽  
Juliana Rosenblat ◽  
Erika Resetkova ◽  
...  
Keyword(s):  
Clinical Management ◽  
Core Biopsy ◽  
Epithelial Atypia

Role of percutaneous needle core biopsy in diagnosis and clinical management of renal masses

2015 ◽  
Vol 46 (4) ◽  
pp. 570-576 ◽  
Author(s):  
Rong Hu ◽  
Celina Montemayor-Garcia ◽  
Kasturi Das
Keyword(s):  
Clinical Management ◽  
Core Biopsy ◽  
Needle Core Biopsy ◽  
Renal Masses

Percutaneous core biopsy of small renal mass lesions: a diagnostic tool to better stratify patients for surgical intervention

2012 ◽  
Vol 111 (4b) ◽  
pp. E146-E151 ◽  
Author(s):  
Stuart R. Menogue ◽  
Beverley A. O'Brien ◽  
Alexandra L. Brown ◽  
Ronald J. Cohen
Keyword(s):  
Diagnostic Tool ◽  
Core Biopsy ◽  
Renal Mass ◽  
Surgical Intervention ◽  
Small Renal Mass ◽  
Mass Lesions

Benign spindle cell lesions of the breast: a diagnostic approach to solitary fibrous tumour, nodular pseudoangiomatous stromal hyperplasia and nodular fasciitis

2019 ◽  
Vol 72 (6) ◽  
pp. 438-442 ◽  
Author(s):  
Julia R Naso ◽  
Connie G Chiu ◽  
Michelle E Goecke ◽  
Debra Chang ◽  
Carolyn J Shiau
Keyword(s):  
Differential Diagnosis ◽  
Clinical Management ◽  
Core Biopsy ◽  
Spindle Cell ◽  
Solitary Fibrous Tumour ◽  
Accurate Diagnosis ◽  
Diagnostic Approach ◽  
Nodular Fasciitis ◽  
Pseudoangiomatous Stromal Hyperplasia ◽  
Ancillary Studies

Benign spindle cell lesions of the breast include neoplastic and reactive entities that are diagnostically challenging given their rarity and similar histomorphology. Accurate diagnosis on percutaneous core biopsy within this category is essential as some lesions require excision and surveillance, whereas others may be observed. We present three cases of rare benign spindle cell lesions of the breast that reflect the diversity of this group: solitary fibrous tumour, nodular pseudoangiomatous stromal hyperplasia and nodular fasciitis. Through these cases, we discuss the associated differential diagnosis and demonstrate how emerging ancillary studies can be integrated into a diagnostic approach. We highlight distinctive clinical and histopathological features and summarise recent updates to the clinical management of these lesions. An organised approach to the broad differential of spindle cell lesions is essential for appropriate diagnosis and treatment.

66 Significance of Percutaneous Biopsy in the Clinical Management of Renal Masses

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
W Cheah ◽  
S D B Marques ◽  
A Bhuvanagiri ◽  
A Kailasa ◽  
M Thangavelu ◽  
...  
Keyword(s):  
Positive Predictive Value ◽  
Negative Predictive Value ◽  
Predictive Value ◽  
Clinical Management ◽  
Renal Mass ◽  
Percutaneous Biopsy ◽  
Final Analysis ◽  
Health Board ◽  
Renal Masses ◽  
Renal Mass Biopsy

Abstract Aim Percutaneous renal mass biopsy is increasingly used in the management of renal masses. The objective of our study was to determine the significance of percutaneous renal mass biopsy and its impact on clinical management. Method Retrospective study of all patients who had image guided percutaneous renal mass biopsy health-board wide from April 2011 to April 2019. Renal mass biopsies were performed for either a localised or metastatic renal mass. Results of the renal biopsies were compared to final diagnosis to determine diagnostic accuracy measured by sensitivity, specificity, negative predictive value and positive predictive value. Results Out of 429 patients who had a renal biopsy, 91 patients- 55 males (61%) and 36 females (39%) were included in the final analysis. The mean age of the study population was 66 years (range 46-87). Renal mass biopsies were performed using coaxial 18-gauge core needle technique. We categorised patients into two groups (metastatic renal masses and localised renal mass). Sixty-eight patients had biopsies for metastatic disease and 23 patients had biopsies for a localised renal mass. In the localised disease group, the sensitivity was 100%, positive predictive value was 82% (95% CI, 48.2-97.7%) and the negative predictive value was 100% (95% CI, 66.4-100%) (Clopper Pearson Method). For patients with metastatic renal mass the positive predictive value was 83%. Conclusions Percutaneous renal mass biopsy may have a role for metastatic renal cancers that require targeted therapy and localised masses that require curative treatment.

Sign in / Sign up

Export Citation Format

Share Document