Head and neck case of the day. Carotid body tumor.

1997 ◽  
Vol 169 (1) ◽  
pp. 277-277
Author(s):  
C F Lanzieri
Open Medicine ◽  
2010 ◽  
Vol 5 (4) ◽  
pp. 411-416 ◽  
Author(s):  
Sureyya Talay ◽  
Mustafa Abanoz ◽  
Mehmet Ali Kaygin ◽  
Ozgur Dag ◽  
Umit Halici ◽  
...  

AbstractGlomus caroticum tumors, usually used as an alternative term for carotid body tumor, are of neuroectodermal origin and a part of the extra adrenal neuroendocrine system pathologies. These abnormalities are the most frequently detected paraganglioma in the localization of the head and neck. In our report, we present a giant tumor mass on the left side which was operated on successfully with a review of our experience retrospectively. Between the dates of June 1995 and October 2009, 47 patients, all of which had a glomus caroticum tumor, underwent to surgery. Tumor presented a wide variety of size and clinical presentations.


2005 ◽  
Vol 132 (3) ◽  
pp. 520-522 ◽  
Author(s):  
Adam D. Rubin ◽  
Sara S. Cheng ◽  
Carol R. Bradford

Paragangliomas of the larynx are rare neuroendocrine tumors, with fewer than 70 cases reported in the literature. 1 Typically, laryngeal paragangliomas are not found in patients with multicentric or familial paragangliomas. Only 1 case of laryngeal paraganglioma has been reported in a patient with a synchronous lesion elsewhere (carotid body tumor). 2 We report an additional case of a patient with a laryngeal and multiple other paragangliomas.


2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
David LaChance ◽  
Thanh Duc Hoang ◽  
Mohamed K M Shakir

Abstract SDHD Mutation: Nonfunctional paragangliomas presenting as bilateral carotid body tumors with syncope Background: A mutation of the SDHD gene is associated with hereditary paraganglioma-pheochromocytoma (PGL/PCC) syndromes which most commonly originate in the head and neck region, and usually form in the carotid body. Paragangliomas (PGL) can be secretory or non-secretory with about 95% of head and neck PGL being non-secretory. They can rarely present with symptoms due to compression, however, as in this case of a 29 year-old female presenting with syncope. Clinical Case: A 29 year-old female presented for evaluation after syncope. She had a syncopal event and fell down while walking in her home. Syncope was preceded by about 15 minutes of flushing, nausea and palpitations. She reported similar episodes once weekly in the preceding months, which generally lasted an hour. Initial workup included normal vital signs at presentation, normal ECG and echocardiogram, normal TFT, CBC, complete metabolic panel. Subsequent head/neck CT revealed bilateral masses in the carotid bifurcations consistent with carotid body tumors. Further history revealed a family history of bilateral carotid body tumors in her father which had never been evaluated. Plasma and urine metanephrines were normal. She underwent carotid body tumor excision. The left carotid body tumor was successfully excised and pathology revealed a paraganglioma with positive synaptophysin and chromogranin stains. Genetic testing revealed an SDHD (succinate dehydrogenase complex subunit D) gene mutation. Repeat biochemical assessment 4 months later was again negative and patient remained asymptomatic postoperatively. Conclusion: Paragangliomas can be secretory or non-secretory with about 95% of head and neck paragangliomas being non-secretory, as in this case. Symptoms can arise from catecholamine hypersecretion, which generally presents as hypertension, headaches, diaphoresis, flushing, anxiety or palpitations, and can be episodic or sustained, or mass effect. Syncope as a presenting symptom is rare, however, and has not been quantified but only reported in case reports. The exact etiology of syncope in our patient is not clear. Hereditary PGL/PCC syndromes should be suspected in any individual with multiple, recurrent, early-onset (age less than 45 years) or family history of PGL/PCC, as these syndromes are inherited in an autosomal dominant manner.


2017 ◽  
Vol 2 (4) ◽  
Author(s):  
Konstantinos Paraskevopoulos ◽  
Anna Patrikidou ◽  
Angelos Megalopoulos ◽  
Panagiotis Palladas ◽  
Angeliki Cheva ◽  
...  

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P122-P122
Author(s):  
Carsten Christof Boedeker ◽  
Gerd Jurgen Ridder ◽  
Wolfgang Maier ◽  
Hartmut Ph Neumann

Objectives To review our experience with head and neck paragangliomas (HNPs) in patients with von Hippel-Lindau disease (VHL). HNPs are rare tumors, 30% of which have been shown to be hereditary neoplasms. Since 2000,4 different paraganglioma syndromes (PGL 1–4) have been described. VHL is characterized by retinal angiomas, haemongioblastomas of the central nervous system, kidney tumors, pancreatic cysts, and pheochromocytomas. Only 4 cases of VHL patients with HNPs have been published in the international medical literature. We systematically reviewed our VHL registry for patients with HNPs. Methods In 1983 we founded a registry for VHL patients. Until 2008, 395 index cases could be registered. First-degree relatives were offered genetic screening as well. Results Three VHL patients presented with HNPs. One boy (mutation VHL 505 T>C) developed a metastatic pheochromocytoma at age 7. 8 years after treatment, he presented with a right-sided carotid body tumor. Another male patient was diagnosed with a tumor of the right carotid body at age 33 (VHL 404 T>A). Interestingly, there have been no other tumors so far. The third patient was diagnosed with a left carotid body tumor at age 33 (VHL 505 T>C). Currently, she has multiple haemangioblastomas of the spinal cord. Conclusions The 3 cases presented demonstrate the importance of awareness of HNPs as one of the manifestations in VHL. So far this rare association has found very little attention in international medical literature. We suggest that VHL patients should undergo a thorough otolaryngological examination of the head and neck.


2003 ◽  
Vol 85 (1) ◽  
pp. 55-57 ◽  
Author(s):  
Mallika Tewari ◽  
Anurag Dixit ◽  
Ritesh Mongha ◽  
Hari S. Shukla

2018 ◽  
Vol 84 (6) ◽  
pp. 802-804
Author(s):  
Mojtaba Maleki ◽  
Mahdi Safdarian ◽  
Ali Daneshvar

Vascular ◽  
2011 ◽  
Vol 21 (1) ◽  
pp. 23-26
Author(s):  
Hyangkyoung Kim ◽  
Yong-Pil Cho ◽  
Ki-Myung Moon ◽  
Tae-Won Kwon

This report describes a case of a delayed cerebral embolic infarction, after internal carotid artery (ICA) ligation secondary to carotid body tumor resection. We describe a 34-year-old woman who underwent left ICA ligation during a large carotid body tumor surgery. Immediately after surgery, the patient was neurologically asymptomatic; however, she subsequently developed a cerebral embolic infarction nine hours postoperatively. After beginning antiplatelet therapy, all symptoms ultimately resolved, although over a gradual course. Since the ligation of the ICA can cause thromboembolic infarctions of the cerebrum, we contend that antiplatelet agents be administered to prevent and/or treat embolic strokes.


1980 ◽  
Vol 65 (5) ◽  
pp. 702
Author(s):  
John D. Kyrtatas

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