Evaluation of Fixed Dose Combination Perindopril/Amlodipine Influence on Target Organ Damage in Patients with Arterial Hypertension and Ischemic Heart Disease (Results of EPHES Trial)

HYPERTENSION ◽  
2016 ◽  
Vol 0 (2.46) ◽  
pp. 77
Author(s):  
H.D. Radchenko ◽  
L.O. Mushtenko ◽  
O.O. Torbas ◽  
S.M. Kushnir ◽  
O.A. Yarynkina ◽  
...  
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Arterial Hypertension ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ ◽  
Ischemic Heart ◽  
Fixed Dose Combination ◽  
Fixed Dose ◽  
Dose Combination

scholarly journals Efficacy of a fixed-dose combination (amlodipine/losartan) in the treatment of a patient with arterial hypertension, dyslipidemia and obesity

2020 ◽  
pp. 74-78
Author(s):  
V. P. Mikhin
Keyword(s):  
Arterial Hypertension ◽  
Clinical Case ◽  
Target Organ Damage ◽  
Organ Damage ◽  
Target Organ ◽  
Fixed Dose Combination ◽  
Fixed Dose ◽  
High Cardiovascular Risk ◽  
Steady Level ◽  
Dose Combination

The article substantiates the feasibility of combination antihypertensive therapy in patients with arterial hypertension without target organ damage and high cardiovascular risk. The authors consider a clinical case of the use of amlodipine and losartan in a fixed-dose combination (Lozap AM) as part of complex therapy in a patient with arterial hypertension, dyslipidemia and obesity. The clinical case showed the ability of the drug to both achieve a steady level of target blood pressure and improve its daily profile by transferring the Night-peaker type to the Non-dipper type.

scholarly journals Effect of Perindopril / Amlodipine Fixed Combination on Ultrasound Characteristics of Ventricles of the Heart in Patients with Ischemic Heart Disease and Arterial Hypertension

Kardiologiia ◽  
2019 ◽  
Vol 59 (1) ◽  
pp. 22-27 ◽  
Author(s):  
N. V. Drobotya ◽  
S. S. Torosyan ◽  
E. Sh. Guseynova ◽  
M. N. Morgunov
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Arterial Hypertension ◽  
Fixed Combination ◽  
Ischemic Heart ◽  
Fixed Dose ◽  
Significant Positive Effect ◽  
Dose Combination ◽  
Left And Right ◽  
Positive Effect

In a group of 32 patients with combined ischemic heart disease (IHD) and arterial hypertension (AH) we studied dynamics of parameters of blood pressure and ECG 24-hour monitoring, as well as ultrasound structural and functional parameters of left and right ventricles during 3-month therapy with fixed dose combination of perindopril arginine (10.0 mg) and amlodipine (5.0 mg). The obtained results demonstrated significant positive effect of this combination on the geometry, structure and diastolic function of both left and right ventricles, as well as confirmed its high antiischemic and antihypertensive effects.

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