scholarly journals ELECTROPHYSIOLOGICAL EFFECTS OF VALSALVA MANOEUVER DURING EARLY PREGNANCY IN PATIENTS WITH PAROXYSMS OF ORTHODROMIC ATRIOVENTRICULAR TACHYCARDIA

Author(s):  
Fagim Kasymovich Rakhmatullov ◽  
Alsu Muzafyarovna Kuryaeva ◽  
Inessa Jakovlevna Moiseeva ◽  
Larisa Fedorovna Burmistrova ◽  
Nikita Evgen’evich Dyatlov

  Objective: The aim is to study electrophysiological (EPh) indicators of the heart in pregnant women in the first trimester with orthodrome paroxysms of reciprocal atrioventricular tachycardia during the Valsalva test, after a single dose of propafenone and a combination of Valsalva test with propafenone.Methods: Clinical survey, assessment of medical history, physical examination, electrocardiogram (ECG) in 12 leads, Holter ECG monitoring, echocardiography, expert ultrasound examination of the fetus, transesophageal EPh study of the heart, the blood test for electrolytes (potassium, sodium), thyroid hormones (T3, T4, thyroid-stimulating hormone) were included in this study. We examined 28 women during an early gestation.Results: We found that the Valsalva manoeuver, Propanorm, and the combination of the Valsalva manoeuver and Propanorm produced an antiarrhythmic effect through the anterograde and retrograde conduction in reentry.Discussion: The study is the first to reveal that the Valsalva manoeuver influences retrograde conduction in reentry in pregnant patients.Conclusion: We proved that it is necessary to use the Valsalva manoeuver to stop paroxysms of orthodromic atrioventricular tachycardia (POAVRT) in the first trimester of pregnancy. If the manoeuver is ineffective, it is advisable to use Propanorm or combination of Propanorm with Valsalva manoeuver.

2012 ◽  
Vol 207 (4) ◽  
pp. 306.e1-306.e5 ◽  
Author(s):  
Jean-Pierre Bernard ◽  
Howard S. Cuckle ◽  
Julien J. Stirnemann ◽  
Laurent J. Salomon ◽  
Yves Ville

2019 ◽  
Vol 51 (4) ◽  
pp. 416-422
Author(s):  
Guocheng Wang ◽  
Guojun Zhang

Abstract Objective To describe the diverse upper reference limits of serum thyroid stimulating hormone on the same platform for pregnant women in China. Methods The trimester-specific and population-specific TSH reference intervals for pregnant women were established, and then 5 reference intervals on the same platform in China were compared with the reference intervals derived from the present study and the manufacturer. Results The most striking difference in the upper reference limits of TSH among 5 reference intervals on the same platform was shown at the first trimester of pregnancy. The calculated regional prevalence rates of subclinical thyroid diseases varied using the data derived from 30,771 pregnant women who visited the largest obstetric center in our district from 2008 to 2018. Conclusion We reported differences among 7 reference intervals of TSH on the same platform and showed the changing population factors significantly affected them.


Author(s):  
Shahnoza Kamalidinova

To study defects and chromosomal abnormalities of the fetus, we retrospectively analyzed results of comprehensive dynamic survey of 26,404 pregnant women aged 18-50 years old at 6 to 40 weeks of pregnancy. Of them, 25,956 (98.3%) women had physiological course of pregnancy, 448 (1.7%) women had abnormal pregnancy. For the diagnosis of fetal defects, we carried out ultrasound, biochemical, invasive and cytogenetic studies. The results of study showed that the majority of fetal defects and pathological course of pregnancy was noted in women at the age of 21-25 years old, since at this age period women have the highest number of pregnancies. At the older age, we noted a gradual decrease in the number of pregnant women, as well as the number of abnormalities of the fetus. Based on the analysis of the results obtained, we have developed an algorithm for early fetal ultrasound examination. In order to exclude non-developing pregnancy and intrauterine fetal death, as well as for early diagnosis of fetal defects, we recommend screening women in the first trimester of pregnancy.


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