The seroepidemiology and risk factors of West Nile virus infection in blood donors of Fars province, southwest of Iran

2021 ◽  
Author(s):  
Jamal Sarvari ◽  
Seyed Y Hosseini ◽  
Faezeh Mosayebi ◽  
Masoud T Ardekani ◽  
Negar Joharinia ◽  
...  
Keyword(s):  
West Nile Virus ◽  
Blood Donors ◽  
Blood Donation ◽  
West Nile Virus Infection ◽  
Fars Province ◽  
West Nile ◽  
Transfusion Center ◽  
Blood Transfusion Center ◽  
Southwest Of Iran ◽  
Southwest Iran

Aim: To evaluate the frequency of West Nile virus (WNV) in blood donors of the blood transfusion center of Fars province, Iran. Materials & methods: A total of 337 participants referred for blood donation to Fars blood centers were included. The presence of anti-WNV antibodies was analyzed using the WNV IgG ELISA kit. Results: Out of all participants, 76 (22.6%) were positive for anti-WNV IgG antibodies. Our results also showed that the frequency of WNV was associated with the age, educational level, job and city of residency of participants (p < 0.05). Conclusion: The results indicated the high frequency of WNV seropositivity among blood donors in southwest Iran. Accordingly, there is an urgent need to establish an integrated surveillance system for monitoring WNV infection in Iran.

scholarly journals Increase in human West Nile and Usutu virus infections, Austria, 2018

2018 ◽  
Vol 23 (43) ◽  
Author(s):  
Stephan W. Aberle ◽  
Jolanta Kolodziejek ◽  
Christof Jungbauer ◽  
Karin Stiasny ◽  
Judith H. Aberle ◽  
...  
Keyword(s):  
West Nile Virus ◽  
Blood Donors ◽  
Blood Donation ◽  
Virus Infections ◽  
West Nile Fever ◽  
West Nile ◽  
Usutu Virus ◽  
Neuroinvasive Disease ◽  
Human West Nile Virus ◽  
Imported Cases

Between 28 June and 17 September 2018, 27 cases of human West Nile virus infections were recorded in Austria; four cases of West Nile neuroinvasive disease, 11 cases of West Nile fever, six infections detected by blood donation screening and six imported cases. In addition, 18 cases of human Usutu virus infections (all blood donors) were recorded. This is the highest number of annual infections recorded in Austria since the introduction of both viruses.

The Informed Consent Process in Whole Blood Donation

2008 ◽  
Vol 132 (6) ◽  
pp. 947-951 ◽  
Author(s):  
Lindsay A. Alaishuski ◽  
Rodney D. Grim ◽  
Ronald E. Domen
Keyword(s):  
West Nile Virus ◽  
Informed Consent ◽  
Whole Blood ◽  
Blood Donors ◽  
Blood Donation ◽  
Informed Consent Process ◽  
Positive Test ◽  
Consent Process ◽  
West Nile ◽  
Eligibility Requirements

Abstract Context.—Informed consent in transfusion medicine has been an area lacking of significant research and it is unknown if donors fully comprehend the risks associated with whole blood donation. Objective.—To assess the adequacy of the informed consent process in whole blood donation. Design.—A brief questionnaire was constructed and distributed to whole blood donors visiting various fixed and mobile donor sites of the Central Pennsylvania Blood Bank. Questions consisted of demographic information; donor opinions of information content, length, and comprehension; and a short quiz pertaining to donor risks and eligibility. Results.—Analysis of 849 surveys demonstrated that donors comprehended a mean of 73.5% of the various donor eligibility and risks that were surveyed. Female and younger donors scored statistically higher on comprehension questions compared with male and older counterparts. Donors were most aware of (1) donor eligibility requirements related to acquired immunodeficiency syndrome comprehension, (2) the risk of dizziness postdonation, and (3) having lived in a certain country (93.7%–95.6% comprehension, respectively). Donors were least aware of (1) the risk of a possible referral to a physician for outstanding medical conditions or positive test results, (2) the risk of a positive test result, and (3) West Nile virus testing information (22.4%–49.3% comprehension, respectively). Conclusions.—Whole blood donors believed that they were giving informed consent, but a significant percentage of donors were unaware of several of the risks associated with blood donation, including participation in West Nile virus research testing. Our data suggest that donors do not fully comprehend the risks of whole blood donation and that repetition of information to the donor, and in multiple formats, strengthens the level of comprehension and thus the informed consent process.

West Nile virus infection in blood donors in the New York City area during the 2010 seasonal epidemic

Transfusion ◽  
2012 ◽  
Vol 52 (12) ◽  
pp. 2664-2670 ◽  
Author(s):  
Richard O. Francis ◽  
Donna Strauss ◽  
Joan Dunn Williams ◽  
Shavonne Whaley ◽  
Beth H. Shaz
Keyword(s):  
New York ◽  
New York City ◽  
West Nile Virus ◽  
Virus Infection ◽  
York City ◽  
Blood Donors ◽  
West Nile Virus Infection ◽  
West Nile ◽  
City Area ◽  
Seasonal Epidemic

No evidence of West Nile virus infection in Dutch blood donors

Vox Sanguinis ◽  
2006 ◽  
Vol 90 (3) ◽  
pp. 166-169 ◽  
Author(s):  
M. H. G. M. Koppelman ◽  
M. S. Sjerps ◽  
M. Waal ◽  
H. W. Reesink ◽  
H. T. M. Cuypers
Keyword(s):  
West Nile Virus ◽  
Virus Infection ◽  
Blood Donors ◽  
West Nile Virus Infection ◽  
West Nile

Associations between West Nile virus infection and symptoms reported by blood donors identified through nucleic acid test screening

Transfusion ◽  
2009 ◽  
Vol 49 (2) ◽  
pp. 278-288 ◽  
Author(s):  
Brian Custer ◽  
Hany Kamel ◽  
Nancy E. Kiely ◽  
Edward L. Murphy ◽  
Michael P. Busch
Keyword(s):  
West Nile Virus ◽  
Nucleic Acid ◽  
Virus Infection ◽  
Blood Donors ◽  
West Nile Virus Infection ◽  
West Nile ◽  
Nucleic Acid Test ◽  
Acid Test

scholarly journals Hemogram abnormalities in apparently healthy first-time blood donors in Libreville, Gabon.

2019 ◽  
Author(s):  
Cyrille BISSEYE ◽  
Jophrette Mireille Ntsame Ndong ◽  
Landry Erik Mombo ◽  
Hornéla Christine Minkoue Mambéri ◽  
Guy Mouelet Migolet ◽  
...  
Keyword(s):  
Blood Donors ◽  
Blood Donation ◽  
Complete Blood Count ◽  
Selection Process ◽  
Hypochromic Anemia ◽  
Transfusion Center ◽  
Blood Transfusion Center ◽  
Normochromic Anemia ◽  
First Time ◽  
Apparently Healthy

Background: The objective of this study was to determine complete blood count (CBC) abnormalities in Libreville blood donors to advocate for hemoglobin pre-donation implementation and to take into account CBC results in blood donation qualification. Methods: This retrospective study was conducted with 4573 blood donors in March 2016 and from January to April 2017. CBC was performed using SysmexXP-300TM hematology analyzer (SYSMEX Corporation, Kobe, Japan). Results: Blood donors were predominantly males (83.7%) with an age ranging from 18 to 59 years. The abnormalities of leukocyte, platelet and erythrocyte counts were determined in blood donors. Leukopenia and thrombocytopenia were significantly more common in men than women (29.02% vs 24.4%, p = 0.011 and 16.2% vs 7.5%, p <0.001). Only 1.0% of women and 0.84% of men have leukocytosis, and 0.7% of women and 0.2% of men have thrombocytosis. Anemia was significantly more common in women compared to men (69.4% vs. 45.0%, P <0.001). Normocytic normochromic and normocytic hypochromic anemia were most common among Libreville blood donors with 39.4% and 23.6%; followed by microcytic normochromic (18.7%) and microcytic hypochromic (13.2%) anemia. Normocytic normochromic and normocytic hypochromic anemia were significantly more common in men than in women, whereas microcytic normochromic anemia was more prevalent among women compared to men (34.6% vs. 13.9%, p <0.001). Conclusions: The results of this study clearly show the need to perform a pre-donation hemoglobin test in blood donors and to take into account their hemogram in the blood donation selection process at the Libreville National Blood Transfusion Center. Keywords: Hemogram, Anemia, Blood Donors, Libreville, Gabon.

scholarly journals CCR5 deficiency increases risk of symptomatic West Nile virus infection

2006 ◽  
Vol 203 (1) ◽  
pp. 35-40 ◽  
Author(s):  
William G. Glass ◽  
David H. McDermott ◽  
Jean K. Lim ◽  
Sudkamon Lekhong ◽  
Shuk Fong Yu ◽  
...  
Keyword(s):  
West Nile Virus ◽  
Blood Donors ◽  
Fatal Outcome ◽  
West Nile Virus Infection ◽  
Leukocyte Trafficking ◽  
West Nile ◽  
Chemokine Receptor Ccr5 ◽  
Hardy Weinberg Equilibrium ◽  
The Brain ◽  
Receptor Ccr5

West Nile virus (WNV) is a reemerging pathogen that causes fatal encephalitis in several species, including mouse and human. Recently, we showed that the chemokine receptor CCR5 is critical for survival of mice infected with WNV, acting at the level of leukocyte trafficking to the brain. To test whether this receptor is also protective in man, we determined the frequency of CCR5Δ32, a defective CCR5 allele found predominantly in Caucasians, in two independent cohorts of patients, one from Arizona and the other from Colorado, who had laboratory-confirmed, symptomatic WNV infection. The distribution of CCR5Δ32 in a control population of healthy United States Caucasian random blood donors was in Hardy-Weinberg equilibrium and CCR5Δ32 homozygotes represented 1.0% of the total group (n = 1,318). In contrast, CCR5Δ32 homozygotes represented 4.2% of Caucasians in the Arizona cohort (odds ratios [OR] = 4.4 [95% confidence interval [CI], 1.6–11.8], P = 0.0013) and 8.3% of Caucasians in the Colorado cohort (OR = 9.1 [95% CI, 3.4–24.8], P &lt; 0.0001). CCR5Δ32 homozygosity was significantly associated with fatal outcome in the Arizona cohort (OR = 13.2 [95% CI, 1.9–89.9], P = 0.03). We conclude that CCR5 mediates resistance to symptomatic WNV infection. Because CCR5 is also the major HIV coreceptor, these findings have important implications for the safety of CCR5-blocking agents under development for HIV/AIDS.

scholarly journals Frequency of West Nile Virus Infection in Iranian Blood Donors

2015 ◽  
Vol 32 (3) ◽  
pp. 343-346 ◽  
Author(s):  
Afsaneh Aghaie ◽  
John Aaskov ◽  
Sadegh Chinikar ◽  
Matthias Niedrig ◽  
Soudabeh Banazadeh ◽  
...  
Keyword(s):  
West Nile Virus ◽  
Virus Infection ◽  
Blood Donors ◽  
West Nile Virus Infection ◽  
West Nile
Sign in / Sign up

Export Citation Format

Share Document