scholarly journals Hemogram abnormalities in apparently healthy first-time blood donors in Libreville, Gabon.

Author(s):  
Cyrille BISSEYE ◽  
Jophrette Mireille Ntsame Ndong ◽  
Landry Erik Mombo ◽  
Hornéla Christine Minkoue Mambéri ◽  
Guy Mouelet Migolet ◽  
...  

Background: The objective of this study was to determine complete blood count (CBC) abnormalities in Libreville blood donors to advocate for hemoglobin pre-donation implementation and to take into account CBC results in blood donation qualification. Methods: This retrospective study was conducted with 4573 blood donors in March 2016 and from January to April 2017. CBC was performed using SysmexXP-300TM hematology analyzer (SYSMEX Corporation, Kobe, Japan). Results: Blood donors were predominantly males (83.7%) with an age ranging from 18 to 59 years. The abnormalities of leukocyte, platelet and erythrocyte counts were determined in blood donors. Leukopenia and thrombocytopenia were significantly more common in men than women (29.02% vs 24.4%, p = 0.011 and 16.2% vs 7.5%, p <0.001). Only 1.0% of women and 0.84% of men have leukocytosis, and 0.7% of women and 0.2% of men have thrombocytosis. Anemia was significantly more common in women compared to men (69.4% vs. 45.0%, P <0.001). Normocytic normochromic and normocytic hypochromic anemia were most common among Libreville blood donors with 39.4% and 23.6%; followed by microcytic normochromic (18.7%) and microcytic hypochromic (13.2%) anemia. Normocytic normochromic and normocytic hypochromic anemia were significantly more common in men than in women, whereas microcytic normochromic anemia was more prevalent among women compared to men (34.6% vs. 13.9%, p <0.001). Conclusions: The results of this study clearly show the need to perform a pre-donation hemoglobin test in blood donors and to take into account their hemogram in the blood donation selection process at the Libreville National Blood Transfusion Center. Keywords: Hemogram, Anemia, Blood Donors, Libreville, Gabon.

2021 ◽  
Author(s):  
Jamal Sarvari ◽  
Seyed Y Hosseini ◽  
Faezeh Mosayebi ◽  
Masoud T Ardekani ◽  
Negar Joharinia ◽  
...  

Aim: To evaluate the frequency of West Nile virus (WNV) in blood donors of the blood transfusion center of Fars province, Iran. Materials & methods: A total of 337 participants referred for blood donation to Fars blood centers were included. The presence of anti-WNV antibodies was analyzed using the WNV IgG ELISA kit. Results: Out of all participants, 76 (22.6%) were positive for anti-WNV IgG antibodies. Our results also showed that the frequency of WNV was associated with the age, educational level, job and city of residency of participants (p < 0.05). Conclusion: The results indicated the high frequency of WNV seropositivity among blood donors in southwest Iran. Accordingly, there is an urgent need to establish an integrated surveillance system for monitoring WNV infection in Iran.


2013 ◽  
Vol 94 (1) ◽  
pp. 116-120
Author(s):  
E Y Zangerova

Aim. To detect the weak points of the existing system of blood donors’ draw in, to define the paths of blood donorship development in the Republic of Mari El. Methods. The analysis of the existing system of donorship at the period from 2002 to 2011 was conducted according to the data of combined yearly reports, data of united blood transfusion center of the Republic of Mari El database, data of Russia’s blood transfusion system facilities activity analysis. The changes in the number of blood donors, activity of blood donors, and detection of blood-transmitted diseases markers were evaluated. Results. No need for further significant increase in the number of active donors was detected, since the modern methods of blood and blood components preparation allows to increase the amounts of required blood components by other ways. The decrease in donors’ mean age was registered, the share of donors younger than 30 increased 2.8-fold compared to 2002 and 1.46-fold compared to 2007. The mean age of donors is 33,94±0,14 years, gender distribution (females - 39.2%, males - 60.8%) do not collide with the gender distribution of the general population. The share of plasma donors has significantly increased (4.8-fold in 2011). Since 2009 the share of first-time donors has increased to 42.9%, indicating the instability of the group of people ready to donate blood. Electronic database introduction and active use allows to exclude people with blood-transmitted diseases and other absolute contraindications from donating blood. The share of people willing to donate blood with registered blood-transmitted diseases has relatively dropped from 4.18% in 2007 to 1.42% in 2011. Conclusion. The main goal of blood transfusion services of Mari El Republic is still to increase the number of permanent donors, donating blood regularly, it will allow to increase the safety of blood components produced and provide the blood transfusion services stability.


2019 ◽  
Vol 2 (1) ◽  
pp. 19-24
Author(s):  
O D Damulak ◽  
E D Jatau ◽  
E Ekam ◽  
E Rumji ◽  
R Yakubu ◽  
...  

Blood donation is not readily an altruistic sacrifice in sub-Saharan Africa where microbial infections, maternal haemorrhages, malaria and other tropical diseases that frequently require blood transfusion are daily diagnoses. Blood transfusion safety is hindered by the combined prevailing high rate of Transfusion-Transmissible Infections (TTIs) and poor screening techniques. This study determined the rate of Enzyme-Linked Immuno-Sorbent Assay (ELISA) positive reactions to transfusion-transmissible infections in rapid diagnostic test negative family replacement blood units, compared to the first time voluntarily donated blood. We studied records of blood units collected in a tertiary hospital from donors who scaled pre-donation Rapid diagnostic test (RDT) screening for the human immunodeficiency virus, hepatitis B and hepatitis C viruses and syphilis and rescreened by ELISA techniques at the National Blood Transfusion Service Centre in Jos, along with units from first-time voluntary blood donors. A total of 19562 blood units; 5945 (30.39%) rapid diagnostic tests negative from a linkage hospital and 13617 (69.61%) from first time voluntary donors were screened by ELISA methods for HIV, HBV, HCV, and syphilis. The overall TTIs detected by ELISA was 16.08%, significantly lower among pre-donation rapid screened family replacement blood donors [495(8.32%)] compared to 2651 (19.47%) among first-time voluntary donors; P=0.0001. Fifty-seven (0.96%) HIV, 166 (2.79%) HBV, 137 (2.31%) HCV and 137 (2.31%) syphilis were still detected respectively by ELISA in the pre-screened negative family replacement blood units. The outcome of ELISA screenings of blood collected from first-time volunteer donors were; 143 (1.05%) HIV, 1,486 (10.91%) HBV, 683 (5.02%) HCV, and 339 (2.49%) syphilis. Blood for transfusion should be screened negative at least with ELISA.


Author(s):  
Dr. Surbhi Jain

Background: Blood donor programme is vital to any transfusion service. This process of blood donation involves voluntary and non remunerated blood donors. The objective of donor screening is to minimize the chances of transmitting infectious agents to recipients. Material and Method: The study was conducted during one year duration from 2017-2018. A total of 700 donors are deferred against 9556 blood donors recruited on the basis of clinical history and brief medical examination in blood bank and voluntary blood donation camps. Donors were deferred temporarily or permanently. Result: Out of 700 deferred donors; 546 were voluntary and 154 were replacement blood donors. Male (601) outnumbered female (99). There were 682 temporary and 18 permanent deferral. Most common age group for deferral was 17-30 yrs (490). Common causes included anemia(142), on medication(108), underweight(83) and high blood pressure(72). Conclusion: Donor selection process is a most important preliminary step in blood banking and should follow stringent medical and regulatory rules. Studying and analysing the profile of blood donors will help to identify sections of the population which could be targeted to increase the pool of voluntary blood donors. Every attempt should be made to decrease the donor deferral keeping in view the safety of both donor and recipients. Keywords: Blood donor, Deferral, Voluntary, Temporary, Permanent.


2019 ◽  
Vol 92 (3) ◽  
pp. 288-294 ◽  
Author(s):  
Alain Chabo Byaene ◽  
Zakayi Pius Kabututu ◽  
Dina Moustafa Abou Rayia ◽  
Mohamed Mohamed Adel El‐Sokkary

Author(s):  
Muhammad Arif Mahmood ◽  
Shireen Khawar ◽  
Abdul Hameed Anjum ◽  
Siraj Munir Ahmed ◽  
Shahid Rafiq ◽  
...  

Acute and chronic viral hepatitis are common public health problems in Pakistan, and associated with serious complications. The carrier rate of HBsAg is quoted to be around 10% in general population while the prevalence of HCV in blood donors is 4.8 %. Data regarding the prevalence of hepatitis B and C virus infections among healthy blood donors is well established in Karachi, Rawalpindi, Islamabad, Faisalabad, Lahore and Abbotabad areas, but similar data is not available for Multan population. Data regarding the epidemiology of HIV infection among blood donors is not available at most of the blood transfusion centers. In this study six thousands (6000) consecutive young healthy voluntary blood donors (age 16-50 years) comprising of 5476 males and 524 females, belonging to Multan region were included from "Blood Transfusion Center Nishtar Hospital Multan" & "Fatmid Blood Transfusion Center Multan" and were tested for HbsAg, Anti-HCV and HIV. Prevalence of Hepatitis B, C and HIV Infection was 3.37%, 0.27% and 0% respectively. The reported prevalence figures for HBsAg & Anti-HCV in other studies are quite variable, depending upon screening protocol, study groups selected and methodology of testing. If data from all the blood transfusion centers of Pakistan is collected and published, we can get representative prevalence values of HBV, HCV and HIV infection of the general population.


Author(s):  
Khalid El Bekkaye ◽  
Zaina Sidqi

Metrological verification consists of proving by calibration measurements that specified requirements are met. The result of an audit is a compliance decision followed by re-commissioning or non-compliance followed by an adjustment, repair, decommissioning, or device reform. At the regional blood transfusion center of Oujda, from 2010 to 2018 the number of metrological qualification has increased from 88 to 152 acts with compliance going from 92% to 97%, thus the number of visit for preventive and curative maintenance of the share of external companies has also increased since 2010 to 2018 from 10 annual visits to 43 annual visits, which indicates a strong progressive metrological activity and an important place of the metrological process in the continuity of guaranteeing a safety of the result obtained from the operations carried out for the practitioners and for donor and recipient patients of the blood product. An action plan was implemented to correct the anomalies identified such as the acquisition of new metrology equipment, to predict the change of climatic chambers and non-adapted devices, the acquisition of more sophisticated machines and the establishment of a continuous recording system of the cold chain.


2021 ◽  
Vol 20 (1) ◽  
pp. 1-8
Author(s):  
Mbanga Djimadoum ◽  
Bessimbaye Nadlaou ◽  
Habkréo Mayanna ◽  
Doumdé Georges ◽  
Barro Nicolas

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