scholarly journals An update on susceptibility of individuals to diseases based on ABO blood groups

2019 ◽  
Vol 5 (3) ◽  
pp. 1-8
Author(s):  
Obeagu, Emmanuel Ifeanyi ◽  
Keyword(s):  
Blood Groups ◽  
Abo Blood Groups

scholarly journals Evaluating of the association between ABO blood groups and coronavirus disease 2019 (COVID-19) in Iraqi patients

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Ali H. Ad’hiah ◽  
Risala H. Allami ◽  
Raghdan H. Mohsin ◽  
Maha H. Abdullah ◽  
Ali J. R. AL-Sa’ady ◽  
...  
Keyword(s):  
Blood Groups ◽  
Abo Blood Groups ◽  
Risk Of Death ◽  
Increased Risk ◽  
Fluorescence Probing ◽  
Group A ◽  
Risk Of Disease ◽  
Novel Coronavirus ◽  
Polymorphic System ◽  
Made In

Abstract Background Susceptibility to the pandemic coronavirus disease 2019 (COVID-19) has recently been associated with ABO blood groups in patients of different ethnicities. This study sought to understand the genetic association of this polymorphic system with risk of disease in Iraqi patients. Two outcomes of COVID-19, recovery and death, were also explored. ABO blood groups were determined in 300 hospitalized COVID-19 Iraqi patients (159 under therapy, 104 recovered, and 37 deceased) and 595 healthy blood donors. The detection kit for 2019 novel coronavirus (2019-nCoV) RNA (PCR-Fluorescence Probing) was used in the diagnosis of disease. Results Mean age was significantly increased in patients compared to controls (49.8 ± 11.7 vs. 28.9 ± 6.6 years; p < 0.001). A similar observation was made in recovered (42.1 ± 10.4 vs. 28.9 ± 6.6 years; p < 0.001) and deceased (53.6 ± 9.7 vs. 28.9 ± 6.6 years; p < 0.001) cases. The mean age was also significantly increased in deceased cases compared to recovered cases (53.6 ± 9.7 vs. 42.1 ± 10.4 years; p < 0.001). There were gender-dependent differences in COVID-19 prevalence. The percentage of COVID-19 was higher in males than in females (all cases: 59.7 vs. 40.3%; recovered cases: 55.8 vs. 44.2%). Such male-gender preponderance was more pronounced in deceased cases (67.6 vs. 32.4%). Logistic regression analysis revealed that groups AB and B + AB were significantly associated with increased risk to develop COVID-19 (OR = 3.10; 95% CI 1.59–6.05; pc = 0.007 and OR = 2.16; 95% CI 1.28–3.63; pc = 0.028, respectively). No ABO-associated risk was observed in recovered cases. On the contrary, groups A (OR = 14.60; 95% CI 2.85–74.88; pc = 0.007), AB (OR = 12.92; 95% CI 2.11–79.29; pc = 0.042), A + AB (OR = 14.67; 95% CI 2.98–72.33; pc = 0.007), and A + B + AB (OR = 9.67; 95% CI 2.02–46.24; pc = 0.035) were associated with increased risk of death in deceased cases. Conclusions The findings of this study suggest that group AB may be a susceptibility biomarker for COVID-19, while group A may be associated with increased risk of death.

A novel paper-based assay for the simultaneous determination of Rh typing and forward and reverse ABO blood groups

2015 ◽  
Vol 67 ◽  
pp. 485-489 ◽  
Author(s):  
Julaluk Noiphung ◽  
Kwanrutai Talalak ◽  
Irin Hongwarittorrn ◽  
Naricha Pupinyo ◽  
Pannawich Thirabowonkitphithan ◽  
...  
Keyword(s):  
Simultaneous Determination ◽  
Blood Groups ◽  
Abo Blood Groups

scholarly journals Genetic aspects of susceptibility to multiple myeloma

Blood ◽  
1982 ◽  
Vol 59 (6) ◽  
pp. 1286-1291 ◽  
Author(s):  
H Ludwig ◽  
W Mayr
Keyword(s):  
Multiple Myeloma ◽  
Patient Group ◽  
Genetic Factors ◽  
Blood Groups ◽  
Abo Blood Groups ◽  
Hla Association ◽  
Large Patient

Abstract An up-dated survey of the information pertaining to the role of genetic factors in susceptibility to multiple myeloma is attempted. Our own results include the HLA-A, B, and C types in 68 patients, the G1m and Km allotypes in 86 patients, and the frequencies of ABO blood groups in 126 patients with multiple myeloma. The allotype G1m(x) was significantly (p less than 0.05) more frequent in the patient group. Since the results in the literature on a possible HLA association have been inconsistent, all relevant available data were combined for an assessment of 379 patients versus 5041 controls. In this comparatively large patient group, the previously reported increase of HLA-4c (HLA-B5 + B18 + Bw35) complex could be confirmed and identified as a weak (RR = 1.7) but significant (p less than 0.05) association of susceptibility to multiple myeloma with HLA-B5. Evaluation of G1m allotypes in the combined sample of 258 patients and 4550 controls and Km in 179 and 2457, respectively yielded no significant differences.

Relative Risks of Thrombosis and Bleeding in Different ABO Blood Groups

2015 ◽  
Vol 42 (02) ◽  
pp. 112-117 ◽  
Author(s):  
Giuseppe Lippi ◽  
Massimo Franchini
Keyword(s):  
Blood Groups ◽  
Abo Blood Groups ◽  
Relative Risks

scholarly journals Astrocytomas and the ABO Blood Groups

1966 ◽  
Vol 3 (4) ◽  
pp. 274-275 ◽  
Author(s):  
R. R. Strang ◽  
D. Tovi ◽  
J. Lopez
Keyword(s):  
Blood Groups ◽  
Abo Blood Groups

scholarly journals ABO blood groups and Helicobacter pylori cagA infection: evidence of an association

2010 ◽  
Vol 16 (1) ◽  
pp. 87-95 ◽  
Author(s):  
DE Mattos ◽  
JR Cintra ◽  
CC Brandão de Mattos ◽  
F Nakashima ◽  
RCMA Silva ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Blood Groups ◽  
Abo Blood Groups
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