scholarly journals Lobular panniculitis: A manifestation of pancreatic tumor with fatal outcome

2005 ◽  
Vol 13 (3-4) ◽  
pp. 153-155 ◽  
Author(s):  
Marina Jovanovic ◽  
Zoran Golusin ◽  
Aleksandra Petrovic ◽  
Nada Vuckovic ◽  
Silvija Brkic ◽  
...  
Keyword(s):  
Fatal Outcome ◽  
Subcutaneous Fat ◽  
Pancreatic Head ◽  
Skin Lesions ◽  
Skin Condition ◽  
Pancreatic Disease ◽  
Health Condition ◽  
Subcutaneous Fat Necrosis ◽  
General Health Condition ◽  
Lobular Panniculitis

Lobular panniculitis is a skin condition that may be the first sign of underlying pancreatic disease. Though rare, the condition has been sufficiently well defined and pathognomonic, thus making differentiation from idiopathic lobular panniculitis quite possible. A 77-year-old woman was in apparently good general health condition when developed skin lesions in a form of erythematous painful fluctuant nodules localized predominantly on the breast, but also present on the arms, thighs, and trunk. Her serum and urinary amylase levels were respectively 3 and 8 fold higher than normal. On histology, skin biopsy showed acute lobular panniculitis with large foci of adipocyte necrosis. Examination of the breast excluded any specific process other than nodular subcutaneous inflammation, but revealed a tumor of the pancreatic head. The nodules spontaneously ulcerated exuding an oily thick brownish material. Her condition deteriorated, and she became progressively debilitated. The patient died before operation, within the next 3 weeks. Subcutaneous fat necrosis was the first manifestation of an otherwise occult pancreatic disease with fatal outcome.

scholarly journals Subcutaneous fat necrosis of newborn - A rare case report of lobular panniculitis in a neonate

2021 ◽  
Vol 7 (3) ◽  
pp. 264-267
Author(s):  
Samagani Akshay ◽  
Pemmanda Raju Belliappa ◽  
Raveendra Leena
Keyword(s):  
Subcutaneous Fat ◽  
Dietary Vitamin ◽  
Inflammatory Cell Infiltrate ◽  
Fat Necrosis ◽  
Subcutaneous Fat Necrosis ◽  
Danger Signs ◽  
Subcutaneous Nodules ◽  
Recommended Treatment ◽  
Rare Case Report ◽  
Lobular Panniculitis

Subcutaneous fat necrosis of newborn is a rare cutaneous disorder affecting neonates. It usually presents as subcutaneous nodules or plaques, within the first few weeks of life, following an eventful delivery. It is characterized by hypercalcemia, which may present with lethargy, irritability, hypotonia and dehydration, mimicking sepsis. Histopathology is proven to be the gold standard in diagnosis with characteristic lobular panniculitis, mixed inflammatory cell infiltrate and radially arranged crystals. This needs to be differentiated from other causes of lobular panniculitis, as early diagnosis and treatment to prevent long‑term complications are advocated. Education of parents regarding the disease and danger signs of hypercalcemia and weekly monitoring of serum calcium is recommended. Treatment based on rehydration, dietary vitamin D and calcium restriction, Furosemide and prednisolone are considered. We have discussed a case of subcutaneous fat necrosis, in an 8-week-old male baby.Key Messages: Subcutaneous fat necrosis is an important differential in neonates presenting with palpable subcutaneous nodules, along with sclerema neonatorum. Severe complications like hypercalcemia should be detected early and managed aggressively to prevent morbidities and mortalities associated with it. Symptomatic management, use of calcium lowering drugs and regular monitoring of calcium levels are recommended.

scholarly journals Nefrocalcinose e Necrose Gorda do Tecido Celular Subcutâneo

2014 ◽  
Vol 28 (1) ◽  
pp. 119 ◽  
Author(s):  
Cláudia Gomes ◽  
Luísa Lobo ◽  
António Siborro Azevedo ◽  
Carla Simão
Keyword(s):  
Chronic Kidney Disease ◽  
Subcutaneous Fat ◽  
Skin Lesions ◽  
Urinary Calcium ◽  
Self Healing ◽  
Fat Necrosis ◽  
Subcutaneous Fat Necrosis ◽  
Prompt Treatment ◽  
Infant Newborn ◽  
Serial Serum

<p>Subcutaneous fat necrosis of the newborn is an uncommon, transient and self-healing panniculits. This entity generally follows an uncomplicated course, however there are rare and important complications. The authors present a case of a newborn with subcutaneous fat necrosis complicated by hypercalcemia and nephrocalcinosis. The pathogenesis of hypercalcemia is not fully understood and the nephrocalcinosis can evolve to chronic kidney disease. Clinicians should be aware of subcutaneous fat necrosis as a possible risk<br />factor for hypercalcemia and patients should have serial serum and urinary calcium determinations for up to 6 months after the appearance of the skin lesions. The early diagnosis and prompt treatment of hypercalcemia are essential to prevent severe complications.<br /><strong>Keywords:</strong> Hypercalcemia; Fat Necrosis; Infant, Newborn; Nephrocalcinosis; Subcutaneous Fat. </p>

scholarly journals Subcutaneous fat necrosis, `polyarthritis', and pancreatic disease

Gut ◽  
1962 ◽  
Vol 3 (2) ◽  
pp. 146-148 ◽  
Author(s):  
P. F. Lucas ◽  
T. K. Owen
Keyword(s):  
Subcutaneous Fat ◽  
Pancreatic Disease ◽  
Fat Necrosis ◽  
Subcutaneous Fat Necrosis

scholarly journals Newborn With Enlarged Erythematous Mass on Back: Case Report and Review of Medical Literature

2018 ◽  
Vol 5 ◽  
pp. 2333794X1880355
Author(s):  
Myo-Sabai Aye ◽  
Maheshwar Mahaseth ◽  
Arlene Rozzelle ◽  
Indira Bhagat ◽  
Prashant Agarwal
Keyword(s):  
Differential Diagnosis ◽  
Medical Literature ◽  
Malignant Tumors ◽  
Subcutaneous Fat ◽  
Skin Condition ◽  
Benign Tumors ◽  
Fat Necrosis ◽  
Subcutaneous Fat Necrosis ◽  
Skin Nodules ◽  
Sclerema Neonatorum

Newborn skin nodules are usually benign and self-resolving skin condition. Differential diagnosis of such lesions include cysts, hemangioma, abscess, cellulitis, sclerema neonatorum, subcutaneous fat necrosis, neurofibromatosis, benign tumors, or malignant tumors such as rhabdomyosarcoma, infantile fibrosarcoma, or neuroblastoma. We report a case of congenital subcutaneous fat necrosis in a 7-day-old baby presenting with multiple erythematous mass on back.

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