scholarly journals Proliferative enteropathy (PE): Induced changes in galanin-like immunoreactivity in the enteric nervous system of the porcine distal colon

2009 ◽  
Vol 59 (4) ◽  
pp. 321-330 ◽  
Author(s):  
Gonkowski S. ◽  
Burlinski P. ◽  
Calka J.
Keyword(s):  
Nervous System ◽  
Enteric Nervous System ◽  
Distal Colon ◽  
Proliferative Enteropathy ◽  
Induced Changes

scholarly journals Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Nick J. Spencer ◽  
Lee Travis ◽  
Lukasz Wiklendt ◽  
Marcello Costa ◽  
Timothy J. Hibberd ◽  
...  
Keyword(s):  
Nervous System ◽  
Smooth Muscle ◽  
Enteric Nervous System ◽  
Lymphatic Vessels ◽  
Distal Colon ◽  
Distal Region ◽  
Proximal Colon ◽  
Synchronous Firing ◽  
Electrophysiological Recordings ◽  
Intrinsic Neurons

AbstractHow the Enteric Nervous System (ENS) coordinates propulsion of content along the gastrointestinal (GI)-tract has been a major unresolved issue. We reveal a mechanism that explains how ENS activity underlies propulsion of content along the colon. We used a recently developed high-resolution video imaging approach with concurrent electrophysiological recordings from smooth muscle, during fluid propulsion. Recordings showed pulsatile firing of excitatory and inhibitory neuromuscular inputs not only in proximal colon, but also distal colon, long before the propagating contraction invades the distal region. During propulsion, wavelet analysis revealed increased coherence at ~2 Hz over large distances between the proximal and distal regions. Therefore, during propulsion, synchronous firing of descending inhibitory nerve pathways over long ranges aborally acts to suppress smooth muscle from contracting, counteracting the excitatory nerve pathways over this same region of colon. This delays muscle contraction downstream, ahead of the advancing contraction. The mechanism identified is more complex than expected and vastly different from fluid propulsion along other hollow smooth muscle organs; like lymphatic vessels, portal vein, or ureters, that evolved without intrinsic neurons.

scholarly journals Localisation and activation of the neurokinin 1 receptor in the enteric nervous system of the mouse distal colon

2014 ◽  
Vol 356 (2) ◽  
pp. 319-332 ◽  
Author(s):  
Juan-Carlos Pelayo ◽  
Nicholas A. Veldhuis ◽  
Emily M. Eriksson ◽  
Nigel W. Bunnett ◽  
Daniel P. Poole
Keyword(s):  
Nervous System ◽  
Enteric Nervous System ◽  
Distal Colon ◽  
Neurokinin 1 Receptor ◽  
Neurokinin 1

Human and Mouse Enteric Nervous System Neurosphere Transplants Regulate the Function of Aganglionic Embryonic Distal Colon

2008 ◽  
Vol 135 (1) ◽  
pp. 205-216.e6 ◽  
Author(s):  
Richard M. Lindley ◽  
Daniel B. Hawcutt ◽  
M. Gwen Connell ◽  
Sarah N. Almond ◽  
Maria–Giuliana Vannucchi ◽  
...  
Keyword(s):  
Nervous System ◽  
Enteric Nervous System ◽  
Distal Colon ◽  
Human And Mouse

Shigella flexneri-induced changes in the neurochemical phenotype of the human enteric nervous system involves a nitrergic pathway

2003 ◽  
Vol 124 (4) ◽  
pp. A74 ◽  
Author(s):  
Emmanuel Coron ◽  
Michel Neunlist ◽  
Philippe Sansonetti ◽  
Jean Paul Galmiche
Keyword(s):  
Nervous System ◽  
Enteric Nervous System ◽  
Shigella Flexneri ◽  
Induced Changes

Age-induced changes in the enteric nervous system in the mouse

1999 ◽  
Vol 107 (1) ◽  
pp. 93-103 ◽  
Author(s):  
Magdy El-Salhy ◽  
Olof Sandström ◽  
Frank Holmlund
Keyword(s):  
Nervous System ◽  
Enteric Nervous System ◽  
Induced Changes
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