scholarly journals Changes in electrocardiogram in patients with cardiac sarcoidosis

2013 ◽  
Vol 66 (suppl. 1) ◽  
pp. 47-49
Author(s):  
Nada Vasic ◽  
Ruza Stevic ◽  
Dragana Jovanovic ◽  
Violeta Mihailovic-Vucinic ◽  
Verica Djukanovic ◽  
...  
Keyword(s):  
Clinical Diagnosis ◽  
Cardiac Sarcoidosis ◽  
Radionuclide Ventriculography ◽  
Rhythm Disturbance ◽  
Technetium 99M ◽  
Conduction Disturbances ◽  
Highly Correlated

Introduction. Abnormalities in the electrocardiogram are more frequent in patients with cardiac sarcoidosis than in those having other diseases. The aim of this study was to determine the types and incidence of abnormalities in the electrocardiogram in patients with cardiac sarcoidosis. Results. The study sample included 30 patients (22 women and 8 men), their mean age being 45 years (23- 64). The clinical diagnosis was confirmed by echocardiography in 25 (83%) and by radionuclide ventriculography technetium-99m in five patients (17%). Abnormal electrocardiograms were found in 28 (93%) patients. The rhythm disturbance was recorded in 21 (69%): arrhythmias in 11 (37%), conduction disturbances in eight (26%), associated in two (6%), changes in the ST-T in 7 (23%). Micro R from V1 to V3 was observed in 15 (50%).patients. The recorded echocardiography granuloma in the septum and occurrence of arrhythmias were highly correlated with electrocardiogram findings ?micro R? V1 to V3 (p <0.007, p <0.02). Conclusion. Unusual, nonspecific changes in the electrocardiogram of patients with cardiac sarcoidosis, such as the finding of reduced tooth R V1-V3, shows a possible affection of the septum and frequent occurrences of dysrhythmias.

scholarly journals Utility of updated diagnositc criteria to detect isolated cardiac sarcoidosis

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
K Sato ◽  
M Yamamoto ◽  
T Ishizu ◽  
M Ieda
Keyword(s):  
Diagnostic Criteria ◽  
Clinical Diagnosis ◽  
Fdg Pet ◽  
Cardiac Involvement ◽  
Cardiac Sarcoidosis ◽  
Histological Finding ◽  
Left Ventricular ◽  
Myocardial Inflammation ◽  
Histologic Diagnosis ◽  
Anti Inflammatory

Abstract Background Prior study reported around one-third of cardiac sarcoidosis (CS) are considered as isolated CS. Detection of CS is challenging due to the limited sensitivity of endomyocardial biopsy and applicability of guidelines, especially in patients without extra-cardiac involvement. Existing diagnostic criteria by Japanese Ministry of health and Welfare (JMHW) or Heart Rhythm Society (HRS) require the presence of extra-cardiac sarcoidosis for clinical diagnosis, isolated CS is not diagnosable in the absence of a positive histological finding. Recently, Japanese Society of Cardiology (JCS) updated diagnostic criteria for CS, which provides the pathway to diagnose isolated CS. Purpose We aimed to assess the reliability of the updated CS guideline in diagnosing CS compared to the prior guidelines. Methods We retrospectively identified 162 consecutive patients who underwent FDG-PET for suspected CS from 2012 through 2019. According to the updated JCS diagnostic criteria, patients were classified as histologic diagnosis of CS, clinical diagnosis of CS, or isolated CS (Figure A). We compared the association between diagnostic criteria and response with anti-inflammatory therapy. Results The JCS criteria classified 24 patients (15%) as having clinical CS, 4 (3%) as histological diagnosis of CS, and 21 (13%) as isolated CS. The JMHW criteria defined 22 patients (14%) as having CS (clinical 11%, histological 3%) and HRS criteria classified 11 patients (7%) as having CS (clinical 4%, histological 3%). Extra-cardiac involvement was detected in 36 patients (22%) with 8% of histological confirmation. Among the 126 patients without extra-cardiac involvement, prevalence of cardiac involvement was higher in isolated CS (P&lt;0.05 for all). Compared with clinical diagnosis group, patients with isolated CS showed higher incident of regional wall motion abnormality (WMA) or left ventricular (LV) dysfunction (p=0.023). In the subgroup of 45 patients with serial FDG-PET evaluation, only updated CS criteria was associate with improvement in myocardial inflammation by FDG-PET (p&lt;0.001). Conclusions Updated JCS diagnostic criteria detects CS patients with active myocardial inflammation which require anti-inflammatory therapy regardless of extra-cardiac involvement better than the prior guidelines. Diagnostic criteria for CS Funding Acknowledgement Type of funding source: None

Can technetium 99m bisdiethylphosphinoethanebis-t butylisocyanide (99mTc-DEPIC) be used for routine radionuclide ventriculography?

1991 ◽  
Vol 18 (5) ◽  
pp. 317-320 ◽  
Author(s):  
John M. H. de Klerk ◽  
Peter P. van Rijk ◽  
Alice J. van Dongen ◽  
Marco Deenstra ◽  
Johan H. Z. Bànki ◽  
...  
Keyword(s):  
Radionuclide Ventriculography ◽  
Technetium 99M

Detection of occult pericardial hemorrhage early after open-heart surgery using technetium-99m red blood cell radionuclide ventriculography

1984 ◽  
Vol 108 (5) ◽  
pp. 1198-1206 ◽  
Author(s):  
Timothy M Bateman ◽  
Lawrence S.C Czer ◽  
Richard J Gray ◽  
Robert M Kass ◽  
Marjorie J Raymond ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Radionuclide Ventriculography ◽  
Open Heart ◽  
Technetium 99M

Experimental evaluation of technetium-99m red blood cell radionuclide ventriculography for detecting pericardial bleeding

1987 ◽  
Vol 113 (4) ◽  
pp. 977-983 ◽  
Author(s):  
Timothy M. Bateman ◽  
Ernest V. Garcia ◽  
Robert M. Kass ◽  
Marjorie J. Raymond ◽  
Morgan E. Stewart ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Experimental Evaluation ◽  
Radionuclide Ventriculography ◽  
Technetium 99M

The Association between Laryngeal Pseudosulcus and Laryngopharyngeal Reflux

2002 ◽  
Vol 126 (6) ◽  
pp. 649-652 ◽  
Author(s):  
Peter C. Belafsky ◽  
Gregory N. Postma ◽  
James A. Koufman
Keyword(s):  
Confidence Interval ◽  
Clinical Diagnosis ◽  
Sensitivity And Specificity ◽  
Vocal Fold ◽  
Laryngopharyngeal Reflux ◽  
Ph Monitoring ◽  
Anterior Commissure ◽  
Ventral Surface ◽  
Double Probe ◽  
Highly Correlated

BACKGROUND: A pattern of edema on the ventral surface of the vocal fold, called pseudosulcus vocalis, was described in 1995. It refers to infraglottic edema extending from the anterior commissure to the posterior larynx. It can be differentiated from sulcus vergeture, which is caused by adhesion of the vocal fold epithelium to the vocal ligament. Although it has been related to laryngopharyngeal reflux (LPR), this has not been thoroughly investigated. PURPOSE: Our goal was to evaluate the association between pseudosulcus and LPR. METHODS: Thirty patients with a clinical diagnosis of LPR confirmed by double-probe pH monitoring and 30 controls without LPR were enrolled. The prevalence of pseudosulcus was determined with fiberoptic laryngoscopy. RESULTS: Seventy percent (21 of 30) of patients with LPR and 30% (9 of 30) of controls had pseudosulcus. Patients with pseudosulcus were 2.3 times more likely to have pH-documented LPR (95% confidence interval 1.3–4.2). The sensitivity and specificity of pseudosulcus in the diagnosis of LPR are 70% and 77%, respectively. CONCLUSIONS: Pseudosulcus is highly correlated with pH-documented LPR ( P < 0.001). The presence of pseudosulcus is suggestive of LPR.

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