Rearing History and Differential Solution Exposure Effects on Two-Bottle Saline Preference

1980 ◽  
Vol 93 (1) ◽  
pp. 147 ◽  
Author(s):  
Roderick Wong
Keyword(s):  
Saline Preference

Sodium chloride preference of genetically hypertensive and normotensive rats

1983 ◽  
Vol 245 (1) ◽  
pp. R38-R44 ◽  
Author(s):  
R. Di Nicolantonio ◽  
F. A. Mendelsohn ◽  
J. S. Hutchinson
Keyword(s):  
Blood Pressure ◽  
Spontaneously Hypertensive Rat ◽  
Sodium Intake ◽  
Bb Rat ◽  
Dark Agouti ◽  
Sprague Dawley ◽  
Saline Preference ◽  
Wistar Kyoto ◽  
Preference Tests ◽  
Genetically Hypertensive

Preference for 0.9% saline was examined, using two-bottle preference tests over 6-7 days, in the spontaneously hypertensive rat (SHR) and normotensive Wistar Kyoto rat (WK) of the Okamoto strain, the genetically hypertensive (GHR) and normotensive rat (NT) of the Smirk strain, and the Sprague-Dawley (SD), Dark Agouti (DA), and hooded Long-Evans or Brattleboro (BB) rat. Only the SHR exhibited a sustained and marked preference for 0.9% saline on each test day. The WK, GHR, NT, and SD preferred saline in the first 24-48 h of testing but thereafter showed neither a preference for, nor aversion to, saline. The BB showed neither a preference for, nor aversion to, saline in the first 24 h of testing and thereafter showed a significant aversion to saline on each test day. Saline preference was further examined in both the SHR and WK offered a choice of water and 0.9%, 2.0, or 2.7% saline. While preference for saline decreased in both SHR and WK with increasing saline concentration, the SHR maintained a significantly greater preference for saline and greater total sodium intake than the WK at each concentration. Hydralazine (5 mg . kg-1 . day-1, po) administered to SHR, while they were offered a choice of water and 0.9% saline, significantly lowered blood pressure over a 4-day period but failed to alter their saline preference significantly. We conclude that of the seven strains of rats examined only the SHR exhibited a preference for saline in extended two-bottle preference tests. Furthermore this preference for saline appears to be maintained independently of the blood pressure of the SHR.

scholarly journals Effects of aging on mineralocorticoid-induced salt appetite in rats

2013 ◽  
Vol 305 (12) ◽  
pp. R1498-R1505 ◽  
Author(s):  
Robert L. Thunhorst ◽  
Terry G. Beltz ◽  
Alan Kim Johnson
Keyword(s):  
Saline Solution ◽  
Brown Norway ◽  
Salt Appetite ◽  
Aged Rats ◽  
Middle Aged ◽  
Renal Handling ◽  
Saline Preference ◽  
Old Rats ◽  
Middle Aged Adult ◽  
Effects Of Aging

This work examined the effects of age on salt appetite measured in the form of daily saline (i.e., 0.3 M NaCl) drinking in response to administration of deoxycorticosterone acetate (DOCA; 5 mg/kg body wt) using young (4 mo), “middle-aged” adult (12 mo), and old (30 mo) male Brown Norway rats. Water and sodium intakes, excretions, and balances were determined daily. The salt appetite response was age dependent with “middle-aged” rats ingesting the most saline solution followed in order by young and then old rats. While old rats drank the least saline solution, the amounts of saline ingested still were copious and comprise an unambiguous demonstration of salt appetite in old rats. Middle-aged rats had the highest saline preference ratios of the groups under baseline conditions and throughout testing consistent with an increased avidity for sodium taste. There were age differences in renal handling of water and sodium that were consistent with a renal contribution to the greater saline intakes by middle-aged rats. There was evidence of impaired renal function in old rats, but this did not account for the reduced saline intakes of the oldest rats.

Effect of deoxycorticosterone on sodium appetite of intact and adrenalectomized rats

1965 ◽  
Vol 208 (6) ◽  
pp. 1281-1285 ◽  
Author(s):  
George Wolf
Keyword(s):  
Sodium Chloride ◽  
Low Doses ◽  
Sodium Appetite ◽  
Self Selection ◽  
Saline Preference ◽  
High Doses ◽  
Adrenalectomized Rats ◽  
Stimulation Of ◽  
Intact Rats

The effect of DOC on sodium chloride (saline) intake was studied in intact and adrenalectomized rats under "two-bottle" self-selection conditions. It was found that in adrenalectomized rats low doses of DOC produced a decrease in saline intake (restoration of sodium-retaining ability), whereas high doses produced an increase in saline intake (stimulation of sodium appetite). At high doses, however, intact rats consumed more saline and manifested a greater preference for it than did similarly treated adrenalectomized rats. Treatment with corticosterone increased both absolute saline intake and saline preference of DOC-treated adrenalectomized rats.

scholarly journals Salt level in weaning diet affects saline preference and fluid intake in Dahl rats.

Hypertension ◽  
1986 ◽  
Vol 8 (11) ◽  
pp. 1021-1026 ◽  
Author(s):  
F Ferrell ◽  
A Lanou ◽  
S D Gray
Keyword(s):  
Fluid Intake ◽  
Salt Level ◽  
Saline Preference

scholarly journals Measured saline preference in the albino rat: the role of non-gustatory factors

1964 ◽  
Vol 1 (1-12) ◽  
pp. 45-46 ◽  
Author(s):  
G. L. Fisher
Keyword(s):  
Albino Rat ◽  
Saline Preference

Electrical stimulation of septum, hypothalamus, and amygdala and saline preference

1971 ◽  
Vol 220 (5) ◽  
pp. 1172-1177 ◽  
Author(s):  
CG Gentil ◽  
GJ Mogenson ◽  
JA Stevenson
Keyword(s):  
Electrical Stimulation ◽  
Saline Preference ◽  
Stimulation Of

scholarly journals Acute and chronic desalivation and isotonic saline preference in rats

1977 ◽  
Vol 5 (2) ◽  
pp. 221-224 ◽  
Author(s):  
Roderick Wong ◽  
Leon Kraintz
Keyword(s):  
Isotonic Saline ◽  
Saline Preference

Saline Preference Curve for Mice: Lack of Relationship to Pigmentation

Nature ◽  
1963 ◽  
Vol 200 (4910) ◽  
pp. 1025-1026 ◽  
Author(s):  
GEORGE WOLF ◽  
GEORGE H. LAWRENCE
Keyword(s):  
Saline Preference ◽  
Preference Curve

Saline preference and body fluid analyses in rats after intrahypothalamic injections of carbachol☆

1968 ◽  
Vol 3 (3) ◽  
pp. 471-475 ◽  
Author(s):  
E STRICKER ◽  
N MILLER
Keyword(s):  
Body Fluid ◽  
Saline Preference
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