Heterophil Response to Intraperitoneal Challenge with Invasion-Deficient Salmonella enteritidis and Salmonella-Immune Lymphokines

1997 ◽  
Vol 41 (2) ◽  
pp. 438 ◽  
Author(s):  
Richard L. Ziprin
Author(s):  
R. B. Moyes ◽  
R. E. Droleskey ◽  
M. H. Kogut ◽  
J. R. DeLoach

Salmonella enteritidis (SE) is of great concern to the poultry industry due to the organism's ability to penetrate the intestinal mucosa of the laying hen and subsequently colonize the ovaries and yolk membrane. The resultant subclinical infection can lead to SE infection of raw eggs and egg products. Interference with the ability of the organism to invade has been linked to the activation and recruitment of inflammatory polymorphonuclear cells, heterophils, to the lamina propria of the intestinal tract.Recently it has been established that heterophil activation and increased resistance to SE organ invasion can be accomplished by the administration of SE-immune lymphokines (SE-ILK) obtained from supernatants of concanavalin-A stimulated SE immune T lymphocytes from SE hyperimmunized hens. Invasion of SE into the lamina propria provides a secondary signal for directing activated heterophils to the site of SE invasion.


2009 ◽  
Vol 8 (9) ◽  
pp. 820-823
Author(s):  
Gabriela V. G- Verduzco ◽  
Guillermo Tellez ◽  
Michael H. Kogut ◽  
Armando Isibasi ◽  
Vianney Ortiz- Navarrete

1999 ◽  
Vol 65 (2) ◽  
pp. 133-143 ◽  
Author(s):  
Lacy L Genovese ◽  
Virginia K Lowry ◽  
Kenneth J Genovese ◽  
John R DeLoach ◽  
Michael H Kogut

1995 ◽  
Vol 39 (1) ◽  
pp. 21 ◽  
Author(s):  
Edward D. McGruder ◽  
Michael H. Kogut ◽  
Donald E. Corrier ◽  
John R. DeLoach ◽  
Billy M. Hargis

1996 ◽  
Vol 40 (1) ◽  
pp. 186 ◽  
Author(s):  
Richard L. Ziprin ◽  
Michael H. Kogut ◽  
Edward D. McGruder ◽  
Billy M. Hargis ◽  
John R. DeLoach

1995 ◽  
Vol 74 (1) ◽  
pp. 18-25 ◽  
Author(s):  
E.D. MCGRUDER ◽  
G.A. RAMIREZ ◽  
M.H. KOGUT ◽  
R.W. MOORE ◽  
D.E. CORRIER ◽  
...  

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