Rejoining of Gamma-Radiation-Induced Single-Strand Breaks in Plasmid DNA by Human Cell Extracts: Dependence on the Concentration of the Hydroxyl Radical Scavenger, Tris

1996 ◽  
Vol 145 (1) ◽  
pp. 24 ◽  
Author(s):  
Paul S. Hodgkins ◽  
Micaela P. Fairman ◽  
Peter O'Neill
Keyword(s):  
Gamma Radiation ◽  
Hydroxyl Radical ◽  
Human Cell ◽  
Plasmid Dna ◽  
Radical Scavenger ◽  
Strand Breaks ◽  
Cell Extracts ◽  
Single Strand Breaks ◽  
Hydroxyl Radical Scavenger ◽  
Radiation Induced

scholarly journals Toxic effects of ozone on murine L929 fibroblasts. Damage to DNA

1987 ◽  
Vol 247 (1) ◽  
pp. 69-72 ◽  
Author(s):  
J Van der Zee ◽  
E Van Beek ◽  
T M A R Dubbelman ◽  
J Van Steveninck
Keyword(s):  
Hydroxyl Radical ◽  
Toxic Effects ◽  
Radical Scavenger ◽  
Strand Breaks ◽  
Model Experiments ◽  
Hydroxyl Radical Scavenger ◽  
Cross Links ◽  
Purines And Pyrimidines

Damage to DNA caused by exposure of L929 fibroblasts to ozone was reflected by the generation of strand breaks, DNA inter-strand cross-links and DNA-protein cross-links. Addition of propan-2-ol, a hydroxyl radical scavenger, did not affect the formation of strand breaks. In model experiments it appeared that both purines and pyrimidines were involved in DNA inter-strand and DNA-protein cross-links.

Arbutin, an intracellular hydroxyl radical scavenger, protects radiation-induced apoptosis in human lymphoma U937 cells

APOPTOSIS ◽  
2014 ◽  
Vol 19 (11) ◽  
pp. 1654-1663 ◽  
Author(s):  
Li-Hua Wu ◽  
Peng Li ◽  
Qing-Li Zhao ◽  
Jin-Lan Piao ◽  
Yu-Fei Jiao ◽  
...  
Keyword(s):  
Hydroxyl Radical ◽  
Radical Scavenger ◽  
U937 Cells ◽  
Hydroxyl Radical Scavenger ◽  
Human Lymphoma ◽  
Radiation Induced ◽  
Induced Apoptosis

Repair of Tandem Base Lesions in DNA by Human Cell Extracts Generates Persisting Single-strand Breaks

2005 ◽  
Vol 351 (5) ◽  
pp. 1020-1029 ◽  
Author(s):  
Helen Budworth ◽  
Gemma Matthewman ◽  
Peter O'Neill ◽  
Grigory L. Dianov
Keyword(s):  
Human Cell ◽  
Single Strand ◽  
Strand Breaks ◽  
Cell Extracts ◽  
Single Strand Breaks

Quantification of Radiation-Induced Single-Strand Breaks in Plasmid DNA using a TUNEL/ELISA-Based Assay

2009 ◽  
Vol 172 (5) ◽  
pp. 529-536 ◽  
Author(s):  
Małgorzata A. Śmiałek ◽  
Sharon A. Moore ◽  
Nigel J. Mason ◽  
David E. G. Shuker
Keyword(s):  
Plasmid Dna ◽  
Single Strand ◽  
Strand Breaks ◽  
Single Strand Breaks ◽  
Radiation Induced
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