Factors Related to Delay in the Diagnosis of Basal Cell Carcinoma

2013 ◽  
Vol 17 (1) ◽  
pp. 27-32 ◽  
Author(s):  
Husein Husein-ElAhmed ◽  
Maria-Teresa Gutierrez-Salmeron ◽  
Ramon Naranjo-Sintes ◽  
Jose Aneiros-Cachaza
Keyword(s):  
Family History ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Diagnostic Delay ◽  
Previous History ◽  
Hospital Setting ◽  
Delay In Diagnosis ◽  
History Of ◽  
Cutaneous Cancer

Background: There is often a delay between the clinical emergence of a basal cell carcinoma (BCC) and the point in time at which the patient presents for definitive diagnosis and treatment. Previously published studies on delays regarding skin cancer have focused on melanoma rather than Bcc. We conducted a study aimed at identifying factors associated with the detection of Bcc and reasons for the delay in diagnosis. Method: A monocentric study was performed. Patients with a primary BCC diagnosed in 2010 were included in the study. They were asked about factors concerning BCC awareness and detection, tumor characteristics, previous history of nonmelanoma cutaneous cancer, family history of nonmelanoma cutaneous cancer, and the presence of comorbidities. Data were analyzed using SPSS software. Results: The mean diagnostic delay for BCC in our hospital setting was estimated at 19.79 ± 14.71 months. Delayed diagnosis was significantly associated with patients over 65 years, those without a previous history of BCC, those without a family history of BCC, those with BCC located elsewhere than the head or neck, and those with lesions not associated with itching or bleeding. Conclusion: This study revealed considerable delay in the diagnosis of BCC. The main reason for delay in the diagnosis seems to be the initial decision of the patient to seek medical advice. These data suggest a need for greater information for the general public on the symptoms and signs that should prompt suspicion of a BCC.

scholarly journals Basal cell carcinoma: an updated epidemiological and therapeutically profile of an urban population

2006 ◽  
Vol 21 (2) ◽  
pp. 66-73 ◽  
Author(s):  
Roberta Lopes Bariani ◽  
Fábio Xerfan Nahas ◽  
Marcus Vinícius Jardini Barbosa ◽  
Andréia Bufoni Farah ◽  
Lydia Masako Ferreira
Keyword(s):  
Skin Cancer ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Actinic Keratosis ◽  
Cell Cancer ◽  
Fatal Outcome ◽  
Previous History ◽  
Basal Cell Cancer ◽  
History Of

PURPOSE: To describe the epidemiological profile of basal cell carcinoma patients at a private hospital in São Paulo and to evaluate the treatment adopted. METHODS: A prospective study of 202 patients, on which 253 lesions were diagnosed for histopathological exam as basal cell carcinoma within the period of January 2001 to September 2003, in the Plastic Surgery Residency Program at the Hospital Jaraguá. The susceptibility factor of the host, the environment variables, the characteristics of the lesions and the efficacy of the treatment were examined. The data were statistically evaluated. RESULTS: The incidence of basal cell carcinoma was 126 cases per 100,000 patients in a period of 32 months (36 cases per 100,000 patients/year). The patients were evenly distributed in terms of sex: 48% male and 52% female. The greater incidence was in patients between the ages of 60 and 80 years and the average was 64 years. The survey revealed susceptibility factors such as white race and phototypes I and II in 95.5% of the patients. Exposition to ultraviolet radiation was reported by 77% of the patients and the most frequent location of tumors was on the face (71.2% of the cases). Actinic keratosis and a history of skin cancer were reported in 43.6% and in 25% of the cases, respectively. The adopted treatment was surgery in 99.4% of the cases and only one patient was treated with radiotherapy. Twenty lesions (8%) had incomplete excision.The recurrence rate was 2% (5 cases). There were no cases with metastasis or fatal outcome. CONCLUSIONS: The factors related to the development of basal cell cancer which were significantly present in the population surveyed were: older age, white individuals, phototypes I and II, presence of actinic keratosis, previous history of non-melanoma skin cancer and exposure to ultra-violet rays both in recreational and in occupational form.The surgical treatment employed was effective with a rate of incomplete excision and recurrence similar to those found in the literature.

scholarly journals Family history of skin cancer is associated with early-onset basal cell carcinoma independent of MC1R genotype

2015 ◽  
Vol 39 (6) ◽  
pp. 1078-1083 ◽  
Author(s):  
Nicholas L. Berlin ◽  
Brenda Cartmel ◽  
David J. Leffell ◽  
Allen E. Bale ◽  
Susan T. Mayne ◽  
...  
Keyword(s):  
Family History ◽  
Skin Cancer ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Early Onset ◽  
History Of

scholarly journals Colonisation of basal cell carcinoma and actinic keratosis by malignant melanoma in situ in a patient with xeroderma pigmentosum variant

2012 ◽  
Vol 2 (2) ◽  
pp. 47 ◽  
Author(s):  
Louise J. Smith ◽  
Ehab A. Husain
Keyword(s):  
Malignant Melanoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Actinic Keratosis ◽  
Xeroderma Pigmentosum ◽  
Clinical Impression ◽  
Anatomical Site ◽  
History Of

Although malignant melanoma (MM) and both basal cell carcinoma (BCC) and actinic keratosis (AK) are sun-induced lesions, the coexistence of these entities at the same anatomical site (collision tumour) is exceedingly rare. We report the case of a 54-year-old woman with a known history of xeroderma pigmentosum variant (XPV) who presented with 2 separate skin lesions over the middle and upper right forearm, respectively. The clinical impression was that of BCCs or squamous cell lesions. On histological examination, both specimens showed features of melanoma <em>in situ </em>(MIS). In the first lesion, MIS merged with and colonised a superficial and focally invasive BCC. In the second lesion, MIS merged with an AK. No separate invasive nests of malignant melanoma were seen in either specimen. The atypical melanocytes were highlighted by Melan-A and HMB-45 immunostaining, whereas the epithelial cells in both the BCC and AK stained with the pancytokeratin MNF-116. The patient had a previous history of multiple MMs and non-melanomatous skin cancers and finally developed widespread metastatic malignant melanoma, which proved fatal. The rare and interesting phenomenon of collision tumours may pose diagnostic difficulties. To our knowledge, this is the first reported simultaneous presentation of cytologically malignant collision tumours in a patient with XPV.

scholarly journals Late malignancy after 26 years of evolution on an untreated perianal fistula

2021 ◽  
Vol 28 (1) ◽  
pp. 99-101
Author(s):  
Lucian Sorin ANDREI ◽  
◽  
Adriana Corina ANDREI ◽  
Alexandru MICU ◽  
Radu Sorin POPISTEANU ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Local Excision ◽  
Squamous Cell ◽  
Basal Cell ◽  
Perianal Fistula ◽  
Transsphincteric Fistula ◽  
History Of ◽  
Histopathological Result

Squamous cell carcinoma and basal cell carcinoma are two types of neoplasms that rarely affect the perianal region, and their etiology is still a matter for debate. We present the case of a 75 year old patient with a 26 year history of perianal fistula, who presents with purulent and fecal perianal discharge and swelling at this level. Physical examination and anoscopy detected low transsphincteric fistula. The biopsy revealed the diagnosis of squamous cell carcinoma, for which a local excision was performed followed by adjuvant radiotherapy. Two years after this event, the patient presented with another perianal lession, which according to the histopathological result was a basal cell carcinoma; local excision was the only treatment performed for this malignancy.

Basal Cell Carcinoma of Scalp in Patients With History of Childhood Therapeutic Radiation

2006 ◽  
Vol 57 (5) ◽  
pp. 509-512 ◽  
Author(s):  
Seyed Esmail Hassanpour ◽  
Abdoljalil Kalantar-Hormozi ◽  
Sadrollah Motamed ◽  
Seiied Mehdie Moosavizadeh ◽  
Reza Shahverdiani
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
History Of Childhood ◽  
History Of ◽  
Therapeutic Radiation

scholarly journals Cutaneous basal cell carcinoma with endobronchial metastasis

2014 ◽  
Vol 96 (7) ◽  
pp. e20-e21 ◽  
Author(s):  
AH Sadr ◽  
S de Kerviler ◽  
N Kang
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Neck Region ◽  
Rare Tumour ◽  
Head And Neck Region ◽  
Basal Cell Carcinomas ◽  
History Of ◽  
Metastatic Basal Cell Carcinoma ◽  
Common Malignancy

Although basal cell carcinoma is a very common malignancy, metastasis from this tumour is extremely rare. For this reason, many plastic surgeons, dermatologists and physicians dealing with skin malignancies consider this as a locally invasive malignancy. We present a rare case of metastatic basal cell carcinoma manifested as a bronchial tumour. This case highlights the fact that despite basal cell carcinoma’s local invasive potential, the possibility of distant metastasis still exists and clinicians should therefore be cautious about interpreting extracutaneous symptoms. Chest physicians should always consider the possibility of this rare tumour in the lungs in patients with a history of large basal cell carcinomas in the head and neck region.

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