scholarly journals Cutaneous basal cell carcinoma with endobronchial metastasis

2014 ◽  
Vol 96 (7) ◽  
pp. e20-e21 ◽  
Author(s):  
AH Sadr ◽  
S de Kerviler ◽  
N Kang
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Neck Region ◽  
Rare Tumour ◽  
Head And Neck Region ◽  
Basal Cell Carcinomas ◽  
History Of ◽  
Metastatic Basal Cell Carcinoma ◽  
Common Malignancy

Although basal cell carcinoma is a very common malignancy, metastasis from this tumour is extremely rare. For this reason, many plastic surgeons, dermatologists and physicians dealing with skin malignancies consider this as a locally invasive malignancy. We present a rare case of metastatic basal cell carcinoma manifested as a bronchial tumour. This case highlights the fact that despite basal cell carcinoma’s local invasive potential, the possibility of distant metastasis still exists and clinicians should therefore be cautious about interpreting extracutaneous symptoms. Chest physicians should always consider the possibility of this rare tumour in the lungs in patients with a history of large basal cell carcinomas in the head and neck region.

scholarly journals Basal Cell Carcinoma of the Nipple: An Uncommon but Ever-Increasing Location

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Yasemin Oram ◽  
Cüyan Demirkesen ◽  
Ayşe Deniz Akkaya ◽  
Erkan Koyuncu
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
English Literature ◽  
Neck Region ◽  
Metastatic Potential ◽  
Regional Lymph Nodes ◽  
Head And Neck Region ◽  
Areola Complex ◽  
Common Malignancy

Basal cell carcinoma (BCC) is the most common malignancy of the skin. It is most frequently seen on the sun-exposed areas of the head and neck region. Occurrence of BCC on the nipple is extremely rare, though the number of the reported cases has been increasing steadily. It has metastatic potential to regional lymph nodes; therefore a more aggressive course can be expected when compared to BCCs located at other sites. Hence, early diagnosis and treatment of BCCs located on this region is of importance. There are 39 reported cases of BCC of nipple-areola complex (NAC) in the English literature. We present an additional case of BCC located on the nipple, presenting with enlargement of the nipple as a sole clinical finding in a 60-year-old man.

scholarly journals Incomplete excision of basal cell carcinoma (BCC) in the head and neck region: to wait, or not to wait?

2017 ◽  
Vol 34 (6) ◽  
pp. 607-611 ◽  
Author(s):  
Jakub Miszczyk ◽  
Michał Charytonowicz ◽  
Tomasz Dębski ◽  
Bartłomiej Noszczyk
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Basal Cell ◽  
Neck Region ◽  
Head And Neck Region ◽  
Incomplete Excision

scholarly journals Metastatic basal cell carcinoma with evidence of intravascular invasion: A case report

2020 ◽  
Vol 8 ◽  
pp. 2050313X1984778
Author(s):  
Lindsey West ◽  
Ramin Fathi ◽  
Rajiv Nijhawan ◽  
Divya Srivastava
Keyword(s):  
High Risk ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
High Risk Factors ◽  
Positron Emission ◽  
Metastatic Basal Cell Carcinoma ◽  
Cervical Level ◽  
Tomography Scan ◽  
Common Malignancy

Although basal cell carcinoma is the most common malignancy in humans, intravascular basal cell carcinoma is rarely reported in the literature. A 78-year-old male presented for Mohs Micrographic surgery of a 1.5 by 1.5 cm2 nodular and focally infiltrative basal cell carcinoma on the left parietal scalp. In the fifth stage, intravascular tumor cells were noted, and the patient was still positive in five out of six specimens with a defect measuring 6.5 × 7.0 cm2. Mohs surgery was stopped due to concern of widespread disease. A positron emission tomography/computed tomography scan was ordered that demonstrated diffuse prominent activity in the cervical level IIa nodes, right sacrum, right scapula, and the third left rib, concerning for metastatic disease. This case emphasizes the importance of vigilance to examine high-risk basal cell carcinoma pathology for intravascular invasion in addition to perineural invasion, especially in the setting of high risk factors for metastatic basal cell carcinoma.

scholarly journals Metastatic Basal Cell Carcinoma: A Biological Continuum of Basal Cell Carcinoma?

2012 ◽  
Vol 2012 ◽  
pp. 1-4
Author(s):  
Karaninder S. Mehta ◽  
Vikram K. Mahajan ◽  
Pushpinder S. Chauhan ◽  
Anju Lath Sharma ◽  
Vikas Sharma ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Neck Region ◽  
Surgical Excision ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Metastatic Basal Cell Carcinoma ◽  
Treat All

Basal cell carcinoma (BCC) accounts for 80% of all nonmelanoma skin cancers. Its metastasis is extremely rare, ranging between 0.0028 and 0.55 of all BCC cases. The usual metastasis to lymph nodes, lungs, bones, or skin is from the primary tumor situated in the head and neck region in nearly 85% cases. A 69-year-old male developed progressively increasing multiple, fleshy, indurated, and at places pigmented noduloulcerative plaques over back, chest, and left axillary area 4 years after wide surgical excision of a pathologically diagnosed basal cell carcinoma. The recurrence was diagnosed as infiltrative BCC and found metastasizing to skin, soft tissue and muscles, and pretracheal and axillary lymph nodes. Three cycles of chemotherapy comprising intravenouscisplatin (50 mg) and 5-florouracil (5-FU, 750 mg) on 2 consecutive days and repeated at every 21 days were effective. As it remains unclear whether metastatic BCC is itself a separate subset of basal cell carcinoma, we feel that early BCC localized at any site perhaps constitutes a biological continuum that may ultimately manifest with metastasis in some individuals and should be evaluated as such. Long-standing BCC is itself potentially at risk of recurrence/dissemination; it is imperative to diagnose and appropriately treat all BCC lesions at the earliest.

Occurrence and recurrence of basal cell carcinoma of the head and neck in negroid and albinoid africans

1987 ◽  
Vol 101 (12) ◽  
pp. 1324-1328 ◽  
Author(s):  
S. A. Ademiluyi ◽  
G. T. A. Ijaduola
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Recurrence Rate ◽  
Basal Cell ◽  
Neck Region ◽  
Head And Neck Region ◽  
Outdoor Workers ◽  
Significant Difference

SummaryA study of sixty patients with basal cell carcinoma of the head and neck region carried out over a six-year period (1979–1985) is hereby presented. Sixteen (26.72 percent) were albinos and 44 (73.28 per cent) negroids. Forty-eight (80 per cent) were outdoor workers. The negroid patients presented between the 3rd and 4th decades while the albinos presented a decade earlier. The commonest site involved in the head and neck was the forehead. The midface showed the highest recurrence rate in both groups, even after adequate excision. The frequency of recurrence in tumours presenting with a size of 2–5 cm. diameter was significantly higher in the albinos than in the negroid (P<0.05), whereas, with tumours of a size larger than 5 cm., there was no statistically significant difference between the albino and the negroid. However, the overall recurrence rate was significantly higher in the albinos (P<0.005). The mortality among the albinos was 25 per cent while there were no deaths in the negroid Africans.

scholarly journals Basal Cell Carcinoma of the Head and Neck Region: An Analysis of 171 Cases

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Omer Sefvan Janjua ◽  
Sana Mehmood Qureshi
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Basal Cell ◽  
Neck Region ◽  
Margin Status ◽  
Anatomical Site ◽  
Female Ratio ◽  
Head And Neck Region ◽  
Malignant Skin Tumors

Objective. To analyze the pattern of presentation of basal cell carcinoma (BCC) and margin status for excised specimens in the head and neck region.Study Design. Retrospective cross-sectional.Duration of Study.January 2009 to December 2011.Methodology. The database of the pathology department was searched to identify records of all malignant skin tumors that underwent standard excision with margins. Out of these records, tumors with a diagnosis of BCC in the head and neck region were retrieved and separated. Age, gender, anatomic location, pattern of tumor, and margin status were noted.Results. A total of 171 cases of BCC from various sites of head and neck were retrieved. Male to female ratio was 1.4 : 1. The age ranged from 22 to 90 years. Seventy-six cases presented on right side, 79 on left, and 16 were in the midline. Most common anatomical site was the nose followed by the cheek. Nodular lesions were the most common (46.2%) followed by pigmented variety (18.7%). Margins were clear in 77 (45.1%) cases, involved in 86 (50.2%) cases, and close in 8 (4.7%) cases.Conclusion. Nose was the most common site followed by the cheek. Nodular and pigmented varieties were the most frequent and margins were involved in more than fifty percent of the cases.

Pilot epidemiological study of basal cell carcinoma in Melaka

2019 ◽  
Vol 10 (6) ◽  
pp. 18-21
Author(s):  
Samuel D Abishegam ◽  
Azira Mat Yasir ◽  
Ilyasak Hussin ◽  
Izety Shezlinda Noran
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Ethnic Group ◽  
Basal Cell ◽  
Neck Region ◽  
Skin Grafting ◽  
Head And Neck Region ◽  
Plastic And Reconstructive Surgery ◽  
Cutaneous Malignancy ◽  
Local Setting

Background: This study was conceptualized to be a stepping stone for analysis of BCC in Melaka. Aims and Objective: To analyse the incidence of BCC in Melaka and analyse the distribution of age, gender, ethnicity, localization of lesion and treatment done. Materials and Methods: A retrospective analysis on patients who were diagnosed and treated for BCC was conducted in the Department of Plastic and Reconstructive Surgery, Hospital Melaka from January 2013 until March 2019. Result: There were 152 patients diagnosed with BCCs (N=152) involving 80 women (52.6%) and 72 men (47.4%) over the study period. The patients were aged between 18–92 years with average age for women were 66.2 years and 66.1 tears for men. The majority of cases, 134 (88.2%) were located on the head and neck region. The most common ethnic group to be affected by BCC is the Chinese with 78 (51.3%) followed by Malays at 72 (47.4%) and 1 (0.7%) for Indians and 1 (0.7%) for other minor ethnic group. There were 89 (58.6%) patients underwent excision only whilst 63 (41.4%) patients underwent excision with reconstruction either with skin grafting or local flap. Conclusion: Basal cell carcinoma is a common cutaneous malignancy. The local demographics of patients with BCC in Melaka are similar to that in the literature. We hope with the data provided, it will facilitate better outcome treatment of BCC not just in our local setting but elsewhere worldwide.

scholarly journals Observation of a unique case of metastatic basal cell carcinoma found by radiographic evaluation in a patient with oculocutaneous albinism

F1000Research ◽  
2014 ◽  
Vol 3 ◽  
pp. 10 ◽  
Author(s):  
Mickaila Johnston ◽  
Whitney Winham ◽  
Nicole Massoll ◽  
Jerad M. Gardner
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Oculocutaneous Albinism ◽  
Ct Imaging ◽  
Radiographic Evaluation ◽  
Pet Ct ◽  
The Usa ◽  
History Of ◽  
Metastatic Basal Cell Carcinoma

Background:Basal cell carcinoma is one of the more common cancers worldwide; 2.8 million are diagnosed annually in the USA.  However, the rate at which it metastasizes is considered very low, between 0.0028 and 0.5%.  For those rare cases in which metastases occur, approximately one third metastasize to the lung. Case:Presented is a 62-year-old Caucasian male with oculocutaneous albinism and a history of basal cell carcinomas occurring in multiple anatomic sites, most recently at the bilateral forearm and back.  Surveillance PET/CT imaging led to the discovery of no less than 30 lung nodules which were consistent with basal cell carcinoma on biopsy.  Histological features were remarkably similar in both the primary tumor and in the metastases.Conclusion:  An unusual case of a non-head and neck primary basal cell carcinoma metastatic to the lung was discovered on surveillance PET/CT imaging, in a patient with oculocutaneous albinism.

Treatment of Basal Cell Carcinoma Located in the Head and Neck Region with Intralesional Interferon ??-2a

2005 ◽  
Vol 25 (10) ◽  
pp. 661-667 ◽  
Author(s):  
Seher Bostanci ◽  
Pelin Kocyigit ◽  
Ay??eg??l Alp ◽  
Cengizhan Erdem ◽  
Erbak G??rgey
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Basal Cell ◽  
Neck Region ◽  
Head And Neck Region
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