Clinical-pharmacological study of oxatomide for allergodermia.Daily one time dosage for atopic dermatitis and urticaria.

1993 ◽  
Vol 55 (1) ◽  
pp. 123-132 ◽  
Author(s):  
TAKAYUKI OYA
Keyword(s):  
Atopic Dermatitis ◽  
Pharmacological Study

scholarly journals GC/MS Analysis of Fatty Acids on Pliek U Oil and Its Pharmacological Study by Molecular Docking to Filaggrin as a Drug Candidate in Atopic Dermatitis Treatment

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Nanda Earlia ◽  
Muslem ◽  
Rivansyah Suhendra ◽  
Mohamad Amin ◽  
C. R. S. Prakoeswa ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Atopic Dermatitis ◽  
Oleic Acid ◽  
Palmitic Acid ◽  
Lauric Acid ◽  
Pharmacological Study ◽  
Gas Chromatography Mass Spectrometry ◽  
Drug Candidate ◽  
Pharmacological Properties ◽  
Control Compound

Analysis of fatty acid contents and pharmacological properties of Pliek U oil was performed. Fatty acids were analyzed by gas chromatography-mass spectrometry (GC-MS), and pharmacological properties based on its potential on filament-aggregating protein (filaggrin) were studied with bioinformatics approach by the reverse docking technique using palmitic acid as a control compound. Two Pliek U extracts, namely, Pliek U oil (PUO) and ethanolic Pliek U oil extract (EPUOE), were prepared. The GC-MS results revealed that lauric acid, myristic acid, palmitic acid, and oleic acid are the predominant fatty acids, with lauric acid being the abundant one in all Pliek U oil extracts. The reverse docking technique results showed that oleic acid had the most stable interaction to filaggrin with the lowest binding affinity (−6.1 kcal/mol). Oleic acid and palmitic acid have one same side binding to filaggrin on amino acid LEU D75. These findings indicated that oleic acid has the best potential to be used as a drug candidate in atopic dermatitis treatment.

Diet and heredity in infantile atopic dermatitis

1972 ◽  
Vol 105 (3) ◽  
pp. 400-404 ◽  
Author(s):  
H. S. Kaufman
Keyword(s):  
Atopic Dermatitis

Reduced histamine reaction in atopic dermatitis

1982 ◽  
Vol 118 (4) ◽  
pp. 244-245 ◽  
Author(s):  
M. Uehara
Keyword(s):  
Atopic Dermatitis
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