scholarly journals Are the Recommended Excision Margins for Basal Cell Carcinoma Too Defensive? A Retrospective Chart Study and Evaluation of the Dutch Guideline

2021 ◽  
Vol 101 (1) ◽  
pp. adv00359
Author(s):  
E Loo ◽  
P Nelemans ◽  
C Peters ◽  
M Abdul-Hamid ◽  
N Kelleners-Smeets
2020 ◽  
Vol 46 (6) ◽  
pp. 753-756 ◽  
Author(s):  
Santiago A. Ariza ◽  
Diana C. Calderón ◽  
Juan C. Aristizábal ◽  
Rafael Parra-Medina

1998 ◽  
Vol 24 (8) ◽  
pp. 921-924 ◽  
Author(s):  
WILLIAM J. GRABSKI ◽  
STUART J. SALASCHE

2019 ◽  
Vol 2019 ◽  
pp. 1-5 ◽  
Author(s):  
Firas Al-Qarqaz ◽  
Khaldon Bodoor ◽  
Awad Al-Tarawneh ◽  
Haytham Eloqayli ◽  
Wisam Al Gargaz ◽  
...  

Introduction.Basal cell carcinoma (BCC) is the most common cancer affecting humans. Luckily it has negligible risk for metastasis; however it can be locally destructive to surrounding tissue. The diagnosis of this tumor relies on clinical and dermoscopic features; however confirmation requires biopsy and histologic examination. Based on clinical and pathologic findings, BCC is classified as low or high risk subtype. The clinician requesting pathology examination for BCC should provide the pathologist with detailed information including patient details, relevant clinical and medical history, site and type of the biopsy, and whether this is a primary or recurrent lesion. The pathologist on the other hand should write an adequate report containing a minimum of core set of parameters including type of BCC, depth of invasion, presence of lymphovascular or perineural invasion, and the excision margins.Objectives.The objective of this study is to evaluate whether requests by clinicians and pathology reports of BCC are adequate.Methods.This is a retrospective analysis done at the dermatology department, faculty of medicine at Jordan University of Science and Technology, Irbid, Jordan. Reports for the period from January 2003 to December 2017 were retrieved and analyzed for data completeness.Results.Most clinical request forms of BCC provided by clinicians are inadequate and lack important relevant information especially in regard to lesion history, patient medical history, and whether BCC is a primary or a recurrent one. Pathology reports for BCC cases also have significant deficiency especially in describing the histologic subtype, depth of invasion, and presence of lymphovascular and perineural invasion. However, the tumor excision margins are adequately described in almost all reports.Conclusions.The study shows that clinicians do not provide adequate clinical information when submitting a request for histopathologic examination of BCC. Similarly, pathologists write incomplete reports that lack important pathologic features. Having pre-set forms (electronic proforma) can help overcome missing information.


Diagnostics ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 120
Author(s):  
Mihai Lupu ◽  
Vlad Mihai Voiculescu ◽  
Ana Caruntu ◽  
Tiberiu Tebeica ◽  
Constantin Caruntu

Complete removal of malignant skin lesions with minimal impact on the aesthetic and functional aspects is the ideal of every dermatologic surgeon. Incomplete surgical excisions and tumor recurrences of basal cell carcinomas (BCC) commonly occur due to the subclinical extension of tumor lateral margins. Presently, the lateral excision margins for BCC cannot be objectively assessed preoperatively, dermoscopy proving to be relatively inefficient in this respect. The question is whether BCC lateral excision margins can be precisely determined preoperatively through the use of complementary non-invasive imaging techniques such as dermoscopy and reflectance confocal microscopy (RCM), thus permitting the complete removal of the lesion in a single stage, estimation of the post-excisional defect, and planning an appropriate reconstruction, especially in medical centers where Mohs micrographic surgery is not available. We present the results of a prospective, histopathologically controlled study designed to determine the feasibility of preoperative, non-invasive, in vivo evaluation of the lateral excision margins for primary basal cell carcinoma, through dermoscopy and RCM.


Author(s):  
Victoria L. Wade ◽  
Winslow G. Sheldon ◽  
James W. Townsend ◽  
William Allaben

Sebaceous gland tumors and other tumors exhibiting sebaceous differentiation have been described in humans (1,2,3). Tumors of the sebaceous gland can be induced in rats and mice following topical application of carcinogens (4), but spontaneous mixed tumors of basal cell origin rarely occur in mice.


2000 ◽  
Vol 39 (5) ◽  
pp. 397-398 ◽  
Author(s):  
Hyoung-Joo Kim ◽  
Youn-Soo Kim ◽  
Ki-Beom Suhr ◽  
Tae-Young Yoon ◽  
Jeung-Hoon Lee ◽  
...  

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