scholarly journals Immunological Mechanisms Underlying the Genetic Predisposition to Severe Staphylococcus aureus Infection in the Mouse Model

2008 ◽  
Vol 173 (6) ◽  
pp. 1657-1668 ◽  
Author(s):  
Maren von Köckritz-Blickwede ◽  
Manfred Rohde ◽  
Sonja Oehmcke ◽  
Lloyd S. Miller ◽  
Ambrose L. Cheung ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Mouse Model ◽  
Genetic Predisposition ◽  
Aureus Infection ◽  
Immunological Mechanisms

scholarly journals A Mouse Model for Ocular Surface Staphylococcus aureus Infection

2017 ◽  
Vol 7 (1) ◽  
pp. 55-63 ◽  
Author(s):  
Zhiyong Zhang ◽  
Osama Abdel-Razek ◽  
Guirong Wang
Keyword(s):  
Staphylococcus Aureus ◽  
Mouse Model ◽  
Ocular Surface ◽  
Aureus Infection

scholarly journals Syndecan-1 (CD138) deficiency increases Staphylococcus aureus infection but has no effect on pathology in a mouse model of peritoneal dialysis

2016 ◽  
Vol 23 (1) ◽  
Author(s):  
Paulina M. Kowalewska ◽  
Uyen T. Nguyen ◽  
Lori L. Burrows ◽  
Alison E. Fox-Robichaud
Keyword(s):  
Staphylococcus Aureus ◽  
Peritoneal Dialysis ◽  
Mouse Model ◽  
Aureus Infection

scholarly journals Immunotherapy Targeting Adenosine Synthase A Decreases Severity of Staphylococcus aureus Infection in Mouse Model

2017 ◽  
Vol 216 (2) ◽  
pp. 245-253 ◽  
Author(s):  
Bao-Zhong Zhang ◽  
JianPiao Cai ◽  
Bin Yu ◽  
Lifeng Xiong ◽  
Qiubin Lin ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Mouse Model ◽  
Aureus Infection

scholarly journals Lysostaphin as a treatment for systemic Staphylococcus aureus infection in a mouse model

2007 ◽  
Vol 60 (5) ◽  
pp. 1051-1059 ◽  
Author(s):  
J. F. Kokai-Kun ◽  
T. Chanturiya ◽  
J. J. Mond
Keyword(s):  
Staphylococcus Aureus ◽  
Mouse Model ◽  
Aureus Infection

scholarly journals IL-4 and IL-13 Produced During Allergic Skin Inflammation Exacerbate Mouse Model of Cutaneous Staphylococcus aureus Infection

2019 ◽  
Vol 143 (2) ◽  
pp. AB66
Author(s):  
Juan-Manuel Leyva-Castillo ◽  
Alexander McGurk ◽  
Raif S. Geha
Keyword(s):  
Staphylococcus Aureus ◽  
Mouse Model ◽  
Skin Inflammation ◽  
Aureus Infection ◽  
Allergic Skin

scholarly journals Anti-infectious activity of synbiotics in a novel mouse model of methicillin-resistant Staphylococcus aureus infection

2010 ◽  
Vol 54 (5) ◽  
pp. 265-275 ◽  
Author(s):  
Enkhtuya Lkhagvadorj ◽  
Satoru Nagata ◽  
Mariko Wada ◽  
Lei Bian ◽  
Chongxin Wang ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Mouse Model ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Methicillin Resistant ◽  
Aureus Infection

scholarly journals Diabetic Mouse Model of Orthopaedic Implant-Related Staphylococcus Aureus Infection

PLoS ONE ◽  
2013 ◽  
Vol 8 (6) ◽  
pp. e67628 ◽  
Author(s):  
Arianna B. Lovati ◽  
Lorenzo Drago ◽  
Lorenzo Monti ◽  
Elena De Vecchi ◽  
Sara Previdi ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Mouse Model ◽  
Diabetic Mouse ◽  
Orthopaedic Implant ◽  
Aureus Infection

scholarly journals Performance of a Four-Antigen Staphylococcus aureus Vaccine in Preclinical Models of Invasive S. aureus Disease

2021 ◽  
Vol 9 (1) ◽  
pp. 177
Author(s):  
Ingrid L. Scully ◽  
Yekaterina Timofeyeva ◽  
Arthur Illenberger ◽  
Peimin Lu ◽  
Paul A. Liberator ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Mouse Model ◽  
Capsular Polysaccharide ◽  
Invasive Disease ◽  
Tissue Infection ◽  
Protective Capacity ◽  
Deep Tissue ◽  
Aureus Infection ◽  
Antigen Vaccine ◽  
Disease Stages

A Staphylococcus aureus four-antigen vaccine (SA4Ag) was designed for the prevention of invasive disease in surgical patients. The vaccine is composed of capsular polysaccharide type 5 and type 8 CRM197 conjugates, a clumping factor A mutant (Y338A-ClfA) and manganese transporter subunit C (MntC). S. aureus pathogenicity is characterized by an ability to rapidly adapt to the host environment during infection, which can progress from a local infection to sepsis and invasion of distant organs. To test the protective capacity of the SA4Ag vaccine against progressive disease stages of an invasive S. aureus infection, a deep tissue infection mouse model, a bacteremia mouse model, a pyelonephritis model, and a rat model of infectious endocarditis were utilized. SA4Ag vaccination significantly reduced the bacterial burden in deep tissue infection, in bacteremia, and in the pyelonephritis model. Complete prevention of infection was demonstrated in a clinically relevant endocarditis model. Unfortunately, these positive preclinical findings with SA4Ag did not prove the clinical utility of SA4Ag in the prevention of surgery-associated invasive S. aureus infection.

Post-operative Staphylococcus aureus infection of a superficial femoral artery stent

VASA ◽  
2013 ◽  
Vol 42 (5) ◽  
pp. 382-386
Author(s):  
Karim Gariani ◽  
Marc Righini ◽  
Marco Roffi ◽  
Gino Gemayel ◽  
Damiano Mugnai ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Femoral Artery ◽  
Superficial Femoral Artery ◽  
Aureus Infection
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