Are antiepidermal transglutaminase antibodies titre correlated with dermatitis herpetiformis lesions during the disease follow-up?

The gluten-free diet (GFD) has gained popularity beyond its main medical indication as the treatment for gluten-induced immune-mediated disorders such as celiac disease (CD), dermatitis herpetiformis, gluten ataxia, wheat allergy, and non-celiac gluten sensitivity. However, the diet carries some disadvantages such as elevated costs, nutritional deficiencies, and social and psychological barriers. The present work aims to review indications, proven benefits, and adverse events of a gluten-free diet. Close follow-up with patients following the diet is recommended. More data is needed to assess the effectiveness of the diet in managing mental and cognitive disorders and to establish a connection between the brain and gluten.

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Celiac disease and dermatitis herpetiformis in Brazilian twins: a long-term follow-up and screening of their relatives

Journal of Pediatric Endocrinology and Metabolism ◽

10.1515/jpem-2012-0282 ◽

2013 ◽

Vol 26 (1-2) ◽

Author(s):

Lorete Maria da Silva Kotze ◽

Renato Nisihara ◽

Luiz Roberto Kotze ◽

Shirley Ramos da Rosa Utiyama

Keyword(s):

Celiac Disease ◽

Dermatitis Herpetiformis ◽

Long Term Follow Up

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Dermatitis herpetiformis in children: a long‐term follow‐up study

British Journal of Dermatology ◽

10.1111/bjd.13047 ◽

2014 ◽

Vol 171 (5) ◽

pp. 1242-1243 ◽

Cited By ~ 14

Author(s):

K. Hervonen ◽

T.T. Salmi ◽

K. Kurppa ◽

K. Kaukinen ◽

P. Collin ◽

...

Keyword(s):

Dermatitis Herpetiformis ◽

Follow Up Study ◽

Long Term Follow Up

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The Long-Term Safety and Quality of Life Effects of Oats in Dermatitis Herpetiformis

Nutrients ◽

10.3390/nu12041060 ◽

2020 ◽

Vol 12 (4) ◽

pp. 1060

Author(s):

Anna Alakoski ◽

Kaisa Hervonen ◽

Eriika Mansikka ◽

Timo Reunala ◽

Katri Kaukinen ◽

...

Keyword(s):

Quality Of Life ◽

Coeliac Disease ◽

Dermatitis Herpetiformis ◽

Gastrointestinal Symptoms ◽

Long Term Follow Up ◽

Assess Quality

The treatment of choice for dermatitis herpetiformis (DH), a cutaneous manifestation of coeliac disease, is a life-long gluten-free diet (GFD). In a GFD, wheat, rye and barley should be strictly avoided, but the role of oats is more controversial. This study aimed to investigate the safety and long-term quality of life and health effects of oat consumption in 312 long-term treated DH patients. Baseline data were gathered from patient records and follow-up data from questionnaires or interviews, and validated questionnaires were used to assess quality of life. We found that altogether 256 patients (82%) were consuming oats as part of their GFD at the follow-up. Long-term follow-up data showed that there were no differences in the presence of long-term illnesses, coeliac disease complications or the usage of medication between those consuming and not consuming oats. However, oat consumers had a better quality of life and reported ongoing gastrointestinal symptoms less frequently (4% vs 19%, p = 0.004) at the follow-up than those not consuming oats. The study established that oats are safe for DH patients and in the long-term seem to improve the quality of life of DH patients.

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Therapy and prevention for mental health: What if mental diseases are mostly not brain disorders?

Behavioral and Brain Sciences ◽

10.1017/s0140525x1800105x ◽

2019 ◽

Vol 42 ◽

Cited By ~ 2

Author(s):

John P. A. Ioannidis

Keyword(s):

Mental Health ◽

Mental Disease ◽

Brain Disorders ◽

Social Stressors ◽

Labor Education ◽

Mental Diseases ◽

Long Term Follow Up ◽

Political Decisions

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.

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Brief summary of Kleť photographic search programme for minor planets

International Astronomical Union Colloquium ◽

10.1017/s0252921100031419 ◽

1999 ◽

Vol 173 ◽

pp. 189-192

Author(s):

J. Tichá ◽

M. Tichý ◽

Z. Moravec

Keyword(s):

Ccd Camera ◽

Minor Planet ◽

Minor Planets ◽

Main Belt

AbstractA long-term photographic search programme for minor planets was begun at the Kleť Observatory at the end of seventies using a 0.63-m Maksutov telescope, but with insufficient respect for long-arc follow-up astrometry. More than two thousand provisional designations were given to new Kleť discoveries. Since 1993 targeted follow-up astrometry of Kleť candidates has been performed with a 0.57-m reflector equipped with a CCD camera, and reliable orbits for many previous Kleť discoveries have been determined. The photographic programme results in more than 350 numbered minor planets credited to Kleť, one of the world's most prolific discovery sites. Nearly 50 per cent of them were numbered as a consequence of CCD follow-up observations since 1994.This brief summary describes the results of this Kleť photographic minor planet survey between 1977 and 1996. The majority of the Kleť photographic discoveries are main belt asteroids, but two Amor type asteroids and one Trojan have been found.

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