scholarly journals Outcomes and dynamic changes of the mitral valve after surgical repair of mitral regurgitation in patients with an atrial septal defect

2019 ◽  
Vol 3 (4) ◽  
pp. 158-164
Author(s):  
Ok Jeong Lee ◽  
Jinyoung Song ◽  
June Huh ◽  
I-Seok Kang ◽  
Ji-Hyuk Yang ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Atrial Septal Defect ◽  
Septal Defect ◽  
Surgical Repair ◽  
Dynamic Changes

scholarly journals Marfan syndrome with unileaflet mitral valve, moderate mitral regurgitation and atrial septal defect. An uncommon association

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Nilda Espinola-Zavaleta ◽  
Rodrigo Escalante-Armenta ◽  
Dana Leyla Rei-Cassab ◽  
Luis Javier Castellanos-Vizcaíno ◽  
Erick Alexanderson-Rosas
Keyword(s):  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Atrial Septal Defect ◽  
Marfan Syndrome ◽  
Septal Defect

scholarly journals Congenital Ostium Secundum Atrial Septal Defect with Mitral Valve Prolapse and Mitral Regurgitation – A Case Report and Review of Literature

2018 ◽  
Vol 12 (2) ◽  
pp. 91-94
Author(s):  
Md Aslam Hossain ◽  
Dharmendra Joshi ◽  
Mayank Acharya ◽  
Tareq Morshed ◽  
Omar Sadeque Khan ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Atrial Septal Defect ◽  
Mitral Valve Prolapse ◽  
Septal Defect ◽  
Dramatic Improvement ◽  
Review Of Literature ◽  
Secundum Atrial Septal Defect ◽  
Asd Closure ◽  
Symptoms And Signs

Mitral regurgitation (MR) associated with secundum Atrial Septal Defect (ASD) is not widely recognized but the association is not unusual. MR has been found in less than 10% of adults with large ASD which is mainly caused by mitral valve prolapse (MVP). We are reporting a case of congenital ostium secundum ASD with MVP associated with MR, review the clinical relevance of this association, and discuss the related literature. Our patient has shown dramatic improvement in symptoms and signs after ASD closure with mitral valve replacement along with improvement in tricuspid regurgitation. More general awareness of this association will further help the surgeon for better management of the patient with this rather unusual combination of lesions.University Heart Journal Vol. 12, No. 2, July 2016; 91-94

Left atrial pressure is associated with iatrogenic atrial septal defect after mitral valve clip

Heart ◽  
2018 ◽  
Vol 105 (11) ◽  
pp. 864-872 ◽  
Author(s):  
Hiroki Ikenaga ◽  
Atsushi Hayashi ◽  
Takafumi Nagaura ◽  
Satoshi Yamaguchi ◽  
Jun Yoshida ◽  
...  
Keyword(s):  
New York ◽  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Atrial Septal Defect ◽  
Septal Defect ◽  
Heart Association ◽  
Functional Class ◽  
Systolic Pulmonary Artery Pressure ◽  
New York Heart Association ◽  
Iatrogenic Atrial Septal Defect

ObjectivesMitral valve (MV) clip procedure requires interatrial trans-septal puncture to access the left atrium (LA). Iatrogenic atrial septal defect (iASD) is not uncommon and may remain for a while. However, haemodynamic and echocardiographic determinants of persistent iASD are not well investigated. We sought to find haemodynamic and echocardiographic determinants of iASD after MV clip.MethodsA total of 131 patients with grades 3 to 4+ mitral regurgitation who underwent MitraClip and completed invasive haemodynamic measurement, baseline, 1 month and approximately 12 months of transthoracic echocardiography (TTE) follow-up were retrospectively reviewed.ResultsTTE at 1 month showed persistent iASD in 57% (1M-iASD). Mean LA pressure after clip was significantly higher in patients with 1M-iASD than patients without 1M-iASD (17±6 mm Hg vs 15±5 mm Hg, p=0.01). Among patients with 1M-iASD, 24 patients (35%) had persistent iASD at 12 months (12M-iASD). Mean LA pressure after clip was significantly higher in patients with 12M-iASD than patients without 12M-iASD (19±6 mm Hg vs 16±6 mm Hg, p=0.04). Patients with 12M-iASD did not significantly differ from patients without 12M-iASD in terms of right heart enlargement, estimated systolic pulmonary artery pressure, New York Heart Association functional class and brain natriuretic peptide at 12 months. Logistic regression analysis, however, showed that mean LA pressure after clip was significantly associated with persistent iASD at 12 months in patients with 1M-iASD even after adjustment for cardiac index after clip and the prevalence of mitral regurgitation ≥3+ at 12 months (OR 1.10 per 1 mm Hg, 95% CI 1.01 to 1.21, p=0.04).ConclusionsElevated LA pressure after MV clip was associated with persistent iASD.

scholarly journals Surgical Correction of Cardiac Defects with Ellis Van Crevald Syndrome – A Rare Case Report

2021 ◽  
Vol 24 (1) ◽  
pp. E009-E013
Author(s):  
DIR Choudhury ◽  
Saikat DasGupta ◽  
Mauin Uddin ◽  
Siddhartha Shankar Howlader ◽  
PK Chanda ◽  
...  
Keyword(s):  
Case Report ◽  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Rare Case ◽  
Autosomal Recessive ◽  
Septal Defect ◽  
Surgical Repair ◽  
Autosomal Recessive Disorder ◽  
Cardiac Defects ◽  
Rare Case Report

Ellis-Van Creveld (EVC) syndrome is an autosomal recessive disorder. Around 150 cases are described in published literature and in Bangladesh, it is even rare.  The patient usually comes with short stature, dental deformity, and cardiac deformity. Here, we present the case of a patient with ostium primum atrial septal defect (ASD) with moderate mitral regurgitation who underwent surgical repair of ASD and mitral valve replacement.

scholarly journals Combined transcatheter treatment of severe mitral regurgitation and secundum atrial septal defect in an inoperable patient: a case report

2021 ◽  
Author(s):  
Fabian Barbieri ◽  
Ulf Landmesser ◽  
Mario Kasner ◽  
Markus Reinthaler
Keyword(s):  
Heart Failure ◽  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Atrial Septal Defect ◽  
Mitral Valve Repair ◽  
Septal Defect ◽  
Defect Closure ◽  
Secundum Atrial Septal Defect ◽  
Valve Repair ◽  
Atrial Septal Defect Closure

Abstract Background Chronic mitral regurgitation is one of the most common valvular heart diseases and is associated with poor outcome. Although other structural diseases are regularly seen in such patients, concomitant atrial septal defects remain a rarity in the elderly. Case summary We report a case of an 82-year old woman with progressive right-sided heart failure due to mitral regurgitation and an atrial septal defect of secundum type, despite optimal medical therapy. Combined transcatheter mitral valve repair by utilizing a separate transseptal puncture and atrial septal defect closure was performed resulting in amelioration of symptoms. Discussion Procedural planning for simultaneous transcatheter therapies of coupled structural heart disease entities remains complex. Our case illustrates feasibility of percutaneous edge-to-edge mitral valve repair and consecutive closure of a large secundum atrial septal defect. Different options of accessing the left atrium should be discussed on an individual basis, while additional atrial septal defect closure may be beneficial in terms of right ventricular function and symptoms of right heart failure.

Cleft of the mitral valve in patients with Down's syndrome

2002 ◽  
Vol 12 (1) ◽  
pp. 27-31 ◽  
Author(s):  
Alain Fraisse ◽  
Tony Abdel Massih ◽  
Damien Bonnet ◽  
Daniel Sidi ◽  
Jean Kachaner
Keyword(s):  
Mitral Valve ◽  
Ventricular Septal Defect ◽  
Atrial Septal Defect ◽  
Septal Defect ◽  
Surgical Repair ◽  
Ductus Arteriosus ◽  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Atrioventricular Septal Defect ◽  
Atrial Septal Defect Closure

Differentiation between a cleft of the mitral valve and the cleft of the left side of an atrioventricular septal defect – a lesion commonly found in patients with Down's syndrome – is surgically important since the distribution of the conduction tissue varies between the 2 lesions. We sought to determine if cleft of the mitral valve occurs also in patients with Down's syndrome. We studied 5 patients with Down's syndrome and cleft of the mitral valve followed in our institution. Echocardiography showed in all 5 patients a cleft dividing the anterior (aortic) leaflet of mitral valve with normal papillary muscle position, mural leaflet size, and ratio of the inlet/outlet dimension of the left ventricle. Associated cardiac lesions were present in all 5 patients: perimembranous ventricular septal defect in 3, ostium secundum atrial septal defect in 2 and patent ductus arteriosus in 2 patients. During the 5.6 years (0.2–11) of the follow-up period, surgical repair of the cleft was never indicated since the mitral regurgitation through the cleft remained mild or absent in all the patients. Two patients underwent closure of a ventricular septal defect, with atrial septal defect closure in one and ductal ligation in 2. One patient died suddenly at home, without evidence of a cardiac cause. In conclusion, a cleft of the mitral valve has important developmental and morphologic differences with atrioventricular septal defect and may occur in patients with Down's syndrome. If surgical repair of the cleft or of associated cardiac lesion is indicated, it is necessary to distinguish it from atrioventricular septal defect where the conduction axis is displaced posteriorly and may be exposed during surgery.

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