scholarly journals Contrast Echocardiography

2016 ◽  
Vol 21 (1) ◽  
pp. 2
Author(s):  
Mark A Friedman
Keyword(s):  
Myocardial Perfusion ◽  
Contrast Agents ◽  
Contrast Echocardiography ◽  
Nuclear Imaging ◽  
Ultrasound Contrast Agents ◽  
Imaging Studies ◽  
Non Invasive ◽  
Ultrasound Contrast ◽  
Significant Research ◽  
Ultrasound Technology

Ultrasound contrast agents are widely used in clinical practice for left ventricle opacification in sub-optimal echocardiograms. Recently, significant research has focused on the use of contrast echocardiography as a non invasive means to evaluate myocardial perfusion. Advances in contrast agents as well as ultrasound technology have enabled investigations into myocardial contrast echocardiography as a possible alternative to nuclear imaging studies. This review will focus on the development and current uses of contrast echocardiography, as well as future indications, including myocardial perfusion and risk stratification following myocardial infarction. 

Stress-induced Myocardial Ischaemia – Perfusion Contrast Echocardiography to Evaluate Presence and Severity of Coronary Artery Disease

2011 ◽  
Vol 7 (3) ◽  
pp. 172
Author(s):  
Benoy Nalin Shah ◽  
Roxy Senior ◽  
◽  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Perfusion ◽  
Contrast Echocardiography ◽  
Evidence Base ◽  
Suspected Coronary Artery Disease ◽  
Ultrasound Contrast Agents ◽  
Prognostic Information ◽  
Non Invasive ◽  
Artery Disease

The development of stable transpulmonary ultrasound contrast agents (UCAs) has allowed the echocardiographic assessment of myocardial perfusion, a technique known as myocardial contrast echocardiography (MCE). MCE exploits the ultrasonic properties of UCAs, which consist of acoustically active gas-filled microspheres. These are intravascular agents that have a rheology similar to red blood cells and thus allow analysis of myocardial blood flow both at rest and after stress. The combined assessment of wall motion and myocardial perfusion provides significant diagnostic and prognostic information during stress echocardiography. Functional imaging tests, such as myocardial perfusion scintigraphy and stress cardiac magnetic resonance imaging, are also used for non-invasive assessment of coronary disease. The principal advantages of MCE are that it does not expose the patient to ionising radiation or radioactive pharmaceuticals, is not contraindicated in patients with an implanted metallic device or who suffer from claustrophobia and it can be performed at the bedside. The purpose of this article is to outline the physiological principles underpinning ischaemia testing with MCE before proceeding to review the evidence base for MCE in patients with known or suspected coronary artery disease.

scholarly journals Non-invasive estimation of blood pressure using ultrasound contrast agents

2010 ◽  
Vol 3 (1) ◽  
pp. 245-253 ◽  
Author(s):  
Klaus Scheldrup Andersen ◽  
Jørgen Arendt Jensen
Keyword(s):  
Blood Pressure ◽  
Contrast Agents ◽  
Ultrasound Contrast Agents ◽  
Non Invasive ◽  
Ultrasound Contrast

Contrast echocardiography

2016 ◽  
Author(s):  
Asrar Ahmed ◽  
Leda Galiuto ◽  
Mark Monaghan ◽  
Roxy Senior
Keyword(s):  
Contrast Agents ◽  
Contrast Echocardiography ◽  
Ultrasound Contrast Agents ◽  
Clinical Settings ◽  
Basic Principles ◽  
Track Record ◽  
Ultrasound Contrast ◽  
Microbubble Contrast Agents ◽  
Appropriate Education ◽  
And Training

Contrast echocardiography is an established and widely used technique employing gas-filled ultrasound contrast agents for diagnosis of cardiovascular disease, and contrast agents have become an integral part of a modern echocardiographic laboratory. Contrast echocardiography has been shown to improve diagnostic accuracy, reproducibility, and confidence across a range of indications with reduced downstream costs. Microbubble contrast agents now have a proven safety track record and it is imperative that through appropriate education and training, use of contrast is encouraged in day-to-day clinical and echocardiographic practice. This chapter discusses the basic principles of contrast echocardiography and reviews the utility of this technique in different clinical settings.

scholarly journals Acoustically-Stimulated Nanobubbles: Opportunities in Medical Ultrasound Imaging and Therapy

2021 ◽  
Vol 9 ◽  
Author(s):  
Brandon Helfield ◽  
Yiran Zou ◽  
Naomi Matsuura
Keyword(s):  
Contrast Agents ◽  
Ultrasound Contrast Agent ◽  
Ultrasound Contrast Agents ◽  
Medical Ultrasound ◽  
Specific Therapy ◽  
Medical Ultrasound Imaging ◽  
Non Invasive ◽  
Ultrasound Contrast ◽  
Scaling Down

Medical ultrasound is one of the most widely used imaging modalities worldwide. Microbubbles, typically ~1–8 μm in diameter, are ultrasound contrast agents confined to the vasculature due to their size. Microbubbles have broadened the scope of medical ultrasound, permitting real-time imaging of the microvasculature for blood flow assessment, molecular imaging, and even non-invasive site-specific therapy. Recently, there has been increasing interest in developing submicron, “nanoscale” agents to extend the utility of medical ultrasound. In this review, we discuss the development of lipid-encapsulated, acoustically responsive, nanobubbles (~200–800 nm in diameter), a next-generation ultrasound contrast agent. First, medical ultrasound and bubble-based contrast agents are introduced, followed by the advantages of scaling down bubble size from an acoustic and biological viewpoint. Next, we present how lipid-encapsulated nanobubbles can be developed toward meeting clinically meaningful endpoints, from agent synthesis and characterization to in vivo considerations. Finally, future opportunities of nanobubbles for advanced applications in ultrasound diagnostic and therapeutic medicine are proposed.

scholarly journals Миокардиальная контрастная стресс-эхокардиография: современное состояние метода

2019 ◽  
Author(s):  
M.A. Saidova ◽  
L.S. Atabaeva ◽  
V.N. Shitov
Keyword(s):  
Clinical Trials ◽  
Image Quality ◽  
Myocardial Perfusion ◽  
Contrast Agents ◽  
Stress Echocardiography ◽  
Wall Motion ◽  
Ultrasound Contrast Agents ◽  
Improve Image Quality ◽  
Ultrasound Contrast ◽  
The World

Миокардиальная контрастная стресс-эхокардиография (МКСЭ) широко используется во всем мире для повышения информативности нагрузочной эхокардиографии в диагностике ишемии миокарда, а также для улучшения качества визуализации у пациентов с плохим ультразвуковым окном . Использование современных ультразвуковых контрастных препаратов позволяет оценивать не только региональную и глобальную сократимость левого желудочка, но и проводить анализ перфузии миокарда. В настоящее время разработаны четкие рекомендации по проведению контрастных исследований в различных клинических группах пациентов. Высокий профиль безопасности ультразвуковых контрастных препаратов нового поколения доказан большим количеством клинических исследований, а сам метод завоевывает все больший интерес у специалистов.Myocardial contrast stress-echocardiography is widely used all over the world to improve image quality, reproducibility and reader confidence in the interpretation of the obtained images. The use of contrast in stress echocardiography has now extended beyond region wall motion to evaluation of myocardial perfusion. The clear recommendations for the use of ultrasound contrast have now been established in various patient populations. Safety of ultrasound contrast agents established in a large number of clinical trials.

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