Detection of Atrial Fibrillation Driver Locations Using CNN and Body Surface Potentials

Author(s):  
Miguel Angel Camara-Vazquez ◽  
Ismael Hernandez-Romero ◽  
Eduardo Morgado-Reyes ◽  
Maria S Guillem ◽  
Andreu M Climent ◽  
...  
2021 ◽  
Vol 12 ◽  
Author(s):  
Miguel Ángel Cámara-Vázquez ◽  
Ismael Hernández-Romero ◽  
Eduardo Morgado-Reyes ◽  
Maria S. Guillem ◽  
Andreu M. Climent ◽  
...  

Atrial fibrillation (AF) is characterized by complex and irregular propagation patterns, and AF onset locations and drivers responsible for its perpetuation are the main targets for ablation procedures. ECG imaging (ECGI) has been demonstrated as a promising tool to identify AF drivers and guide ablation procedures, being able to reconstruct the electrophysiological activity on the heart surface by using a non-invasive recording of body surface potentials (BSP). However, the inverse problem of ECGI is ill-posed, and it requires accurate mathematical modeling of both atria and torso, mainly from CT or MR images. Several deep learning-based methods have been proposed to detect AF, but most of the AF-based studies do not include the estimation of ablation targets. In this study, we propose to model the location of AF drivers from BSP as a supervised classification problem using convolutional neural networks (CNN). Accuracy in the test set ranged between 0.75 (SNR = 5 dB) and 0.93 (SNR = 20 dB upward) when assuming time independence, but it worsened to 0.52 or lower when dividing AF models into blocks. Therefore, CNN could be a robust method that could help to non-invasively identify target regions for ablation in AF by using body surface potential mapping, avoiding the use of ECGI.


Author(s):  
Miguel Ángel Cámara-Vázquez ◽  
Adrián Oter-Astillero ◽  
Ismael Hernández-Romero ◽  
Miguel Rodrigo ◽  
Eduardo Morgado-Reyes ◽  
...  

Heart Rhythm ◽  
2021 ◽  
Vol 18 (8) ◽  
pp. S404
Author(s):  
Grant R. Simons ◽  
David Y. Feigenblum ◽  
John E. McCann ◽  
Dmitry Nemirovsky

2021 ◽  
Vol 12 ◽  
Author(s):  
Amel Karoui ◽  
Mostafa Bendahmane ◽  
Nejib Zemzemi

One of the essential diagnostic tools of cardiac arrhythmia is activation mapping. Noninvasive current mapping procedures include electrocardiographic imaging. It allows reconstructing heart surface potentials from measured body surface potentials. Then, activation maps are generated using the heart surface potentials. Recently, a study suggests to deploy artificial neural networks to estimate activation maps directly from body surface potential measurements. Here we carry out a comparative study between the data-driven approach DirectMap and noninvasive classic technique based on reconstructed heart surface potentials using both Finite element method combined with L1-norm regularization (FEM-L1) and the spatial adaptation of Time-delay neural networks (SATDNN-AT). In this work, we assess the performance of the three approaches using a synthetic single paced-rhythm dataset generated on the atria surface. The results show that data-driven approach DirectMap quantitatively outperforms the two other methods. In fact, we observe an absolute activation time error and a correlation coefficient, respectively, equal to 7.20 ms, 93.2% using DirectMap, 14.60 ms, 76.2% using FEM-L1 and 13.58 ms, 79.6% using SATDNN-AT. In addition, results show that data-driven approaches (DirectMap and SATDNN-AT) are strongly robust against additive gaussian noise compared to FEM-L1.


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