Tympanic membrane penetrating trauma with CSF leak leading to pneumococcal meningitis in an infant

AbstractWe report the case of an eighteen-month-old child who suffered a tympanic membrane perforation caused by a digital thermometer. This injury led to a CSF leak. The patient was followed conservatively with no surgical intervention or prophylactic antibiotic therapy and developed pneumococcal meningitis 7 days later. He was then treated with Ceftriaxone for 12 days with full recovery, from a short and long term perspective. Issues concerning the management of CSF leak will be discussed along with review of the literature. This is the first report of post-traumatic meningitis as a result of mild trauma not involving maxillofacial or basilar fractures. The aim of our report is to raise awareness to this cause of meningitis and to stress the importance of immunizing against Streptococcal pneumoniae, a measure which may have prevented the sequelae in our case.

Download Full-text

Evaluating short and long term outcomes following pediatric Myringoplasty with Gelfoam graft for tympanic membrane perforation following ventilation tube insertion

Journal of Otolaryngology - Head and Neck Surgery ◽

10.1186/s40463-019-0363-6 ◽

2019 ◽

Vol 48 (1) ◽

Cited By ~ 5

Author(s):

Jin Soo Song ◽

Gerard Corsten ◽

Liane B. Johnson

Keyword(s):

Tympanic Membrane ◽

Tympanic Membrane Perforation ◽

Ventilation Tube ◽

Long Term Outcomes ◽

Tube Insertion ◽

Membrane Perforation ◽

Short And Long Term

Download Full-text

Eardrum perforation treatment blood plasma enriched with platelet growth factors

Medical Council ◽

10.21518/2079-701x-2021-12-110-115 ◽

2021 ◽

pp. 110-115

Author(s):

A. I. Kriukov ◽

A. V. Gurov ◽

A. G. Ermolaev ◽

Z. V. Murzakhanova ◽

T. K. Dubovaya ◽

...

Keyword(s):

Growth Factors ◽

Blood Plasma ◽

Tympanic Membrane ◽

Tympanic Membrane Perforation ◽

Main Group ◽

Control Group ◽

Relative Area ◽

Membrane Perforation ◽

Post Traumatic

Introduction. The problem of the development of acute post-traumatic otitis media has not lost its relevance. Long-term preservation of the defect of the tympanic membrane contributes to the development of chronic inflammation in the middle ear and a deterioration in the quality of life of patients.Objective. To study the effect of blood plasma enriched with platelet growth factors on the regeneration of the tympanic membrane tissues in patients with acute post-traumatic perforation.Materials and methods. Patients with acute post-traumatic perforation of the tympanic membrane were divided into the main (24 people) and control (19 people) groups. Patients of the main group in the area of perforation of the tympanic membrane were injected once by application with a clot of autoplasma, enriched with platelet growth factors. The control group patients underwent dynamic observation of the processes of natural regeneration of the tympanic membrane tissues. On the 5, 10 and 15th days, the tissue regeneration of the tympanic membranes was assessed subjectively (patient complaints, audiometry) and objectively (otoscopy with the calculation of the dynamics of the relative perforation area, otoacoustic emission).Results. A single application of blood plasma enriched with platelet growth factors to the perforation area was significantly more often accompanied by closure of the tympanic membrane perforation (p ≤ 0.01) and a decrease in the average relative area of the tympanic membrane perforation on days 10 and 15 of the study (p ≤ 0.01). The dynamics of the average relative area of the tympanic membrane perforation reflected a high rate of closure of the tympanic membrane defect in the main group. Better healing of the tympanic membrane in patients of the main group was accompanied by an improvement in the auditory function of the affected ear. The quality of hearing was, on average, significantly better in the patients of the main group than in the patients of the control group, both on the 10th and 15th days of observation (p ≤ 0.01).Conclusion. Clinical use of blood plasma enriched with platelet growth factors has a beneficial effect on the rate, intensity of closure of the tympanic membrane perforation and hearing.

Download Full-text